| Dataset | GeneRIF Biological Term Annotations |
| Category | structural or functional annotations |
| Type | biological term |
| Description | oligophrenin 1|This gene encodes a Rho-GTPase-activating protein that promotes GTP hydrolysis of Rho subfamily members. Rho proteins are important mediators of intracellular signal transduction, which affects cell migration and cell morphogenesis. Mutations in this gene are responsible for OPHN1-related X-linked mental retardation with cerebellar hypoplasia and distinctive facial dysmorhphism. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4983) |
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4 genes co-occuring with the biological term ophn1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
