osteoarthritic Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

100 genes co-occuring with the biological term osteoarthritic in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACAN aggrecan
ADAM12 ADAM metallopeptidase domain 12
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
AKT1 v-akt murine thymoma viral oncogene homolog 1
BGN biglycan
BIRC5 baculoviral IAP repeat containing 5
BSG basigin (Ok blood group)
CD151 CD151 molecule (Raph blood group)
CD34 CD34 molecule
CD44 CD44 molecule (Indian blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHI3L2 chitinase 3-like 2
CLU clusterin
COL10A1 collagen, type X, alpha 1
COL1A1 collagen, type I, alpha 1
COL2A1 collagen, type II, alpha 1
COL9A1 collagen, type IX, alpha 1
COMP cartilage oligomeric matrix protein
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
DCN decorin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK2 dickkopf WNT signaling pathway inhibitor 2
ESRRA estrogen-related receptor alpha
FGF23 fibroblast growth factor 23
FRZB frizzled-related protein
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
HRH1 histamine receptor H1
HRH2 histamine receptor H2
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP5 insulin-like growth factor binding protein 5
IHH indian hedgehog
IL10 interleukin 10
IL1B interleukin 1, beta
IL6 interleukin 6
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAV integrin, alpha V
ITGB5 integrin, beta 5
KERA keratocan
LEP leptin
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
LUM lumican
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MIR140 microRNA 140
MIR148A microRNA 148a
MIR27A microRNA 27a
MMP13 matrix metallopeptidase 13
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
PCSK6 proprotein convertase subtilisin/kexin type 6
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PPARG peroxisome proliferator-activated receptor gamma
PRG4 proteoglycan 4
PRKCA protein kinase C, alpha
PRKCZ protein kinase C, zeta
PTEN phosphatase and tensin homolog
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RCOR1 REST corepressor 1
RECK reversion-inducing-cysteine-rich protein with kazal motifs
REST RE1-silencing transcription factor
RUNX2 runt-related transcription factor 2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIRT1 sirtuin 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SOST sclerostin
SOX9 SRY (sex determining region Y)-box 9
SPP1 secreted phosphoprotein 1
TAC1 tachykinin, precursor 1
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP4 TIMP metallopeptidase inhibitor 4
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNC tenascin C
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
VEGFA vascular endothelial growth factor A
VIM vimentin
WISP3 WNT1 inducible signaling pathway protein 3