osteoarthritis Gene Set

Dataset DISEASES Experimental Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans. (Experimental Factor Ontology, EFO_0002506)
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Genes

10 genes associated with the disease osteoarthritis in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
DOT1L DOT1-like histone H3K79 methyltransferase 0.817078
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 0.561725
MCF2L MCF.2 cell line derived transforming sequence-like 0.486425
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) 0.429338
COG5 component of oligomeric golgi complex 5 0.414708
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.297866
SLC30A10 solute carrier family 30, member 10 0.256228
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.15771
FTO fat mass and obesity associated 0.126165
PARD3B par-3 family cell polarity regulator beta 0.080593