osteoblast Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A cell from which bone develops; a bone-forming cell. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001593)
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Genes

205 genes co-occuring with the biological term osteoblast in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACVR1 activin A receptor, type I
ADA adenosine deaminase
ADIPOQ adiponectin, C1Q and collagen domain containing
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPTL4 angiopoietin-like 4
APLN apelin
APP amyloid beta (A4) precursor protein
ARRB1 arrestin, beta 1
ATF6 activating transcription factor 6
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BGLAP bone gamma-carboxyglutamate (gla) protein
BGN biglycan
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
BMPR1B bone morphogenetic protein receptor, type IB
CALCA calcitonin-related polypeptide alpha
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMP cathelicidin antimicrobial peptide
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL3 chemokine (C-C motif) ligand 3
CCND1 cyclin D1
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHD9 chromodomain helicase DNA binding protein 9
CHRDL2 chordin-like 2
COL1A1 collagen, type I, alpha 1
CP ceruloplasmin (ferroxidase)
CSF3 colony stimulating factor 3 (granulocyte)
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNNBIP1 catenin, beta interacting protein 1
CTSD cathepsin D
CXCL10 chemokine (C-X-C motif) ligand 10
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DANCR differentiation antagonizing non-protein coding RNA
DCLK1 doublecortin-like kinase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP1 dual specificity phosphatase 1
DVL1 dishevelled segment polarity protein 1
E2F1 E2F transcription factor 1
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRRA estrogen-related receptor alpha
EWSR1 EWS RNA-binding protein 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP4 fatty acid binding protein 4, adipocyte
FGF2 fibroblast growth factor 2 (basic)
FGF23 fibroblast growth factor 23
FGFR2 fibroblast growth factor receptor 2
FHL2 four and a half LIM domains 2
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT4 fms-related tyrosine kinase 4
FN1 fibronectin 1
FOXC2 forkhead box C2
FPR1 formyl peptide receptor 1
FTH1 ferritin, heavy polypeptide 1
FYN FYN proto-oncogene, Src family tyrosine kinase
FZD1 frizzled class receptor 1
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GFI1 growth factor independent 1 transcription repressor
GJA1 gap junction protein, alpha 1, 43kDa
GPNMB glycoprotein (transmembrane) nmb
GREM1 gremlin 1, DAN family BMP antagonist
HDAC3 histone deacetylase 3
HDAC7 histone deacetylase 7
HHIPL2 HHIP-like 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
HPSE heparanase
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HTRA1 HtrA serine peptidase 1
ICAM1 intercellular adhesion molecule 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP5 insulin-like growth factor binding protein 5
IGFBP6 insulin-like growth factor binding protein 6
IL1B interleukin 1, beta
IL3 interleukin 3
IL6 interleukin 6
INHBA inhibin, beta A
INSL3 insulin-like 3 (Leydig cell)
IP6K1 inositol hexakisphosphate kinase 1
IP6K2 inositol hexakisphosphate kinase 2
IRS2 insulin receptor substrate 2
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA7 integrin, alpha 7
ITLN1 intelectin 1 (galactofuranose binding)
JUND jun D proto-oncogene
KCNK2 potassium channel, two pore domain subfamily K, member 2
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLK3 kallikrein-related peptidase 3
LEF1 lymphoid enhancer-binding factor 1
LEP leptin
LGALS9 lectin, galactoside-binding, soluble, 9
LIF leukemia inhibitory factor
LMNA lamin A/C
LOX lysyl oxidase
LRP1 low density lipoprotein receptor-related protein 1
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
LTBP1 latent transforming growth factor beta binding protein 1
LTF lactotransferrin
LYN LYN proto-oncogene, Src family tyrosine kinase
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MEN1 multiple endocrine neoplasia I
MIR141 microRNA 141
MIR148A microRNA 148a
MIR15B microRNA 15b
MIR27A microRNA 27a
MIR29A microRNA 29a
MIR29B1 microRNA 29b-1
MIR29B2 microRNA 29b-2
MIR378A microRNA 378a
MIR764 microRNA 764
MIR93 microRNA 93
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MN1 meningioma (disrupted in balanced translocation) 1
MSX2 msh homeobox 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBL1 neuroblastoma 1, DAN family BMP antagonist
NELL1 NEL-like 1 (chicken)
NFIL3 nuclear factor, interleukin 3 regulated
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGFR nerve growth factor receptor
NOG noggin
NOTCH1 notch 1
NPNT nephronectin
NR2F2 nuclear receptor subfamily 2, group F, member 2
OSTN osteocrin
PDLIM7 PDZ and LIM domain 7 (enigma)
PDZRN3 PDZ domain containing ring finger 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLAT plasminogen activator, tissue
PPARG peroxisome proliferator-activated receptor gamma
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRL prolactin
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTHLH parathyroid hormone-like hormone
PTK2 protein tyrosine kinase 2
RLN1 relaxin 1
RORA RAR-related orphan receptor A
RSPO1 R-spondin 1
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
SATB2 SATB homeobox 2
SDC2 syndecan 2
SDC4 syndecan 4
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SFRP1 secreted frizzled-related protein 1
SIRT1 sirtuin 1
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLIT2 slit homolog 2 (Drosophila)
SMAD1 SMAD family member 1
SMAD3 SMAD family member 3
SMOC1 SPARC related modular calcium binding 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNAI2 snail family zinc finger 2
SOST sclerostin
SP7 Sp7 transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STMN2 stathmin 2
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TGFB1 transforming growth factor, beta 1
TGFB3 transforming growth factor, beta 3
TGFBI transforming growth factor, beta-induced, 68kDa
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLE3 transducin-like enhancer of split 3
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TP53 tumor protein p53
TP53INP2 tumor protein p53 inducible nuclear protein 2
TP73 tumor protein p73
TSC22D3 TSC22 domain family, member 3
TWIST1 twist family bHLH transcription factor 1
TXNIP thioredoxin interacting protein
WNT10B wingless-type MMTV integration site family, member 10B
WNT3A wingless-type MMTV integration site family, member 3A
WNT5A wingless-type MMTV integration site family, member 5A
WWTR1 WW domain containing transcription regulator 1