osteochondrosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description An ischemic bone disease that results_in necrosis followed by regrowth in children and teens located_in bone. (Human Disease Ontology, DOID_8125)
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Genes

130 genes co-occuring with the disease osteochondrosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
NCDN neurochondrin 1.45089
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 1.28959
IHH indian hedgehog 1.26342
XIRP2 xin actin binding repeat containing 2 1.24776
ACAN aggrecan 1.13755
RBBP9 retinoblastoma binding protein 9 1.12193
SMR3A submaxillary gland androgen regulated protein 3A 1.12024
AMIGO2 adhesion molecule with Ig-like domain 2 1.11645
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 1.103
PTH2R parathyroid hormone 2 receptor 1.06942
WRNIP1 Werner helicase interacting protein 1 1.0606
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 1.0109
C4BPA complement component 4 binding protein, alpha 0.984321
CLCN2 chloride channel, voltage-sensitive 2 0.953273
SOX9 SRY (sex determining region Y)-box 9 0.951187
PHIP pleckstrin homology domain interacting protein 0.890898
AOAH acyloxyacyl hydrolase (neutrophil) 0.888438
EHF ets homologous factor 0.863456
NOTCH1 notch 1 0.84544
IGF1 insulin-like growth factor 1 (somatomedin C) 0.840525
TBX5 T-box 5 0.833148
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.826999
C1QC complement component 1, q subcomponent, C chain 0.808949
ACTG2 actin, gamma 2, smooth muscle, enteric 0.804436
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.799513
MMP13 matrix metallopeptidase 13 0.789262
FAF1 Fas (TNFRSF6) associated factor 1 0.762271
ADAM2 ADAM metallopeptidase domain 2 0.756564
ELOVL2 ELOVL fatty acid elongase 2 0.756564
STRADA STE20-related kinase adaptor alpha 0.752085
PAX1 paired box 1 0.744766
CUL4B cullin 4B 0.732191
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.712796
COL2A1 collagen, type II, alpha 1 0.712392
OGN osteoglycin 0.707559
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.683892
COL9A3 collagen, type IX, alpha 3 0.676706
F5 coagulation factor V (proaccelerin, labile factor) 0.670333
STAG2 stromal antigen 2 0.63907
IVD isovaleryl-CoA dehydrogenase 0.634742
COL5A2 collagen, type V, alpha 2 0.634742
OCM2 oncomodulin 2 0.622967
TLK2 tousled-like kinase 2 0.615138
PTCH2 patched 2 0.608885
OCM oncomodulin 0.604201
HAT1 histone acetyltransferase 1 0.592895
C1QB complement component 1, q subcomponent, B chain 0.592116
COL9A2 collagen, type IX, alpha 2 0.589001
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.585108
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 0.548195
LOX lysyl oxidase 0.545093
TRPS1 trichorhinophalangeal syndrome I 0.51188
FRY furry homolog (Drosophila) 0.507657
COL6A1 collagen, type VI, alpha 1 0.506123
COL10A1 collagen, type X, alpha 1 0.500379
PDE4B phosphodiesterase 4B, cAMP-specific 0.499231
GJA5 gap junction protein, alpha 5, 40kDa 0.494266
COMP cartilage oligomeric matrix protein 0.48893
POSTN periostin, osteoblast specific factor 0.479047
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.469197
NPTXR neuronal pentraxin receptor 0.468063
PPT1 palmitoyl-protein thioesterase 1 0.466928
PTH parathyroid hormone 0.462016
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.446558
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.43941
BAK1 BCL2-antagonist/killer 1 0.427015
FMOD fibromodulin 0.42364
ASPN asporin 0.410535
PTHLH parathyroid hormone-like hormone 0.400453
CP ceruloplasmin (ferroxidase) 0.384822
MMP3 matrix metallopeptidase 3 0.38111
LAX1 lymphocyte transmembrane adaptor 1 0.378514
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 0.365562
PEPD peptidase D 0.35892
HPR haptoglobin-related protein 0.357446
BMP2 bone morphogenetic protein 2 0.356341
RER1 retention in endoplasmic reticulum sorting receptor 1 0.356341
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.356341
UBC ubiquitin C 0.355972
ALPPL2 alkaline phosphatase, placental-like 2 0.354131
ALPP alkaline phosphatase, placental 0.353763
ALPL alkaline phosphatase, liver/bone/kidney 0.353027
RUNX2 runt-related transcription factor 2 0.348981
RPS27A ribosomal protein S27a 0.347511
PROS1 protein S (alpha) 0.346777
PTH1R parathyroid hormone 1 receptor 0.343473
MEF2C myocyte enhancer factor 2C 0.342372
ANGPTL4 angiopoietin-like 4 0.336144
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.336144
F2 coagulation factor II (thrombin) 0.332487
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.328105
BMP6 bone morphogenetic protein 6 0.328105
CASP6 caspase 6, apoptosis-related cysteine peptidase 0.32009
GLI3 GLI family zinc finger 3 0.307395
FGFR3 fibroblast growth factor receptor 3 0.305948
UBB ubiquitin B 0.302337
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 0.291539
NCOA1 nuclear receptor coactivator 1 0.290103
LUM lumican 0.272953
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.264431
BGLAP bone gamma-carboxyglutamate (gla) protein 0.263722
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.26266
HSF4 heat shock transcription factor 4 0.260891
CTGF connective tissue growth factor 0.25877
LEF1 lymphoid enhancer-binding factor 1 0.257358
CRP C-reactive protein, pentraxin-related 0.252422
PFN2 profilin 2 0.247501
EXT1 exostosin glycosyltransferase 1 0.242595
THBD thrombomodulin 0.241895
CTSB cathepsin B 0.234573
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.218715
TGFB1 transforming growth factor, beta 1 0.211934
NOG noggin 0.20658
VCAN versican 0.198064
MPO myeloperoxidase 0.1936
SMO smoothened, frizzled class receptor 0.18621
F10 coagulation factor X 0.182957
IFI44L interferon-induced protein 44-like 0.181222
TGFBI transforming growth factor, beta-induced, 68kDa 0.174617
APAF1 apoptotic peptidase activating factor 1 0.171785
HP haptoglobin 0.170789
LARS leucyl-tRNA synthetase 0.166095
COL1A1 collagen, type I, alpha 1 0.143812
COL1A2 collagen, type I, alpha 2 0.143593
WISP3 WNT1 inducible signaling pathway protein 3 0.143086
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.143065
IRF6 interferon regulatory factor 6 0.142485
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.14242
RNASEH2A ribonuclease H2, subunit A 0.14038
GBA glucosidase, beta, acid 0.138882