osteoclast differentiation Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. (Gene Ontology, GO_0030316)
External Link http://amigo.geneontology.org/amigo/term/GO:0030316
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Genes

25 genes participating in the osteoclast differentiation biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ANXA2 annexin A2
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
BMP2 bone morphogenetic protein 2
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
DCSTAMP dendrocyte expressed seven transmembrane protein
EFNA2 ephrin-A2
EPHA2 EPH receptor A2
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FOXP1 forkhead box P1
GAB2 GRB2-associated binding protein 2
GLO1 glyoxalase I
GPR183 G protein-coupled receptor 183
IGSF23 immunoglobulin superfamily, member 23
MAPK14 mitogen-activated protein kinase 14
OCSTAMP osteoclast stimulatory transmembrane protein
OSCAR osteoclast associated, immunoglobulin-like receptor
OSTM1 osteopetrosis associated transmembrane protein 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SNX10 sorting nexin 10
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TREM2 triggering receptor expressed on myeloid cells 2
TYROBP TYRO protein tyrosine kinase binding protein