osteolysis Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Osteolysis refers to the destruction of bone through bone resorption with removal or loss of calcium. (Human Phenotype Ontology, HP_0002797)
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Genes

31 genes co-occuring with the biological term osteolysis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
AKT1 v-akt murine thymoma viral oncogene homolog 1
BTK Bruton agammaglobulinemia tyrosine kinase
CALCA calcitonin-related polypeptide alpha
CCL3 chemokine (C-C motif) ligand 3
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
DKK2 dickkopf WNT signaling pathway inhibitor 2
FRZB frizzled-related protein
IGF1R insulin-like growth factor 1 receptor
IL11 interleukin 11
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
INHBA inhibin, beta A
MAPKAP1 mitogen-activated protein kinase associated protein 1
MIR30A microRNA 30a
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP3 NLR family, pyrin domain containing 3
RUNX2 runt-related transcription factor 2
SOST sclerostin
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
ZDHHC9 zinc finger, DHHC-type containing 9