osteomalacia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A bone remodeling disease that has_material_basis_in a vitamin D deficiency which results_in softening located_in bone. (Human Disease Ontology, DOID_10573)
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Genes

89 genes co-occuring with the disease osteomalacia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
FGF23 fibroblast growth factor 23 2.79726
PTH parathyroid hormone 2.55448
ALPL alkaline phosphatase, liver/bone/kidney 2.35511
ALPPL2 alkaline phosphatase, placental-like 2 2.33859
ALPP alkaline phosphatase, placental 2.33755
PHEX phosphate regulating endopeptidase homolog, X-linked 2.14073
MEPE matrix extracellular phosphoglycoprotein 1.9727
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 1.68679
KNTC1 kinetochore associated 1 1.64307
BGLAP bone gamma-carboxyglutamate (gla) protein 1.51589
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.48691
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.46232
EMP1 epithelial membrane protein 1 1.44825
KL klotho 1.42805
SPTA1 spectrin, alpha, erythrocytic 1 1.26298
FGF1 fibroblast growth factor 1 (acidic) 1.24732
SFRP4 secreted frizzled-related protein 4 1.22692
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 1.21652
CALCA calcitonin-related polypeptide alpha 1.16093
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 1.10175
DMP1 dentin matrix acidic phosphoprotein 1 0.984743
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.949102
GC group-specific component (vitamin D binding protein) 0.919673
CLCN5 chloride channel, voltage-sensitive 5 0.871643
FAM20C family with sequence similarity 20, member C 0.857724
S100G S100 calcium binding protein G 0.807718
ZNF484 zinc finger protein 484 0.786803
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.782707
TRPV6 transient receptor potential cation channel, subfamily V, member 6 0.730571
MGAM maltase-glucoamylase 0.725716
SLC9C1 solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1 0.713601
FRZB frizzled-related protein 0.709572
FGF7 fibroblast growth factor 7 0.681894
ALB albumin 0.667947
FAM20B family with sequence similarity 20, member B 0.59991
ACPP acid phosphatase, prostate 0.583163
SFRP1 secreted frizzled-related protein 1 0.569941
FDXR ferredoxin reductase 0.563723
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 0.553239
HYI hydroxypyruvate isomerase (putative) 0.535022
SST somatostatin 0.514956
SOST sclerostin 0.514186
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.489691
GCM2 glial cells missing homolog 2 (Drosophila) 0.476772
PTHLH parathyroid hormone-like hormone 0.471846
LIN37 lin-37 DREAM MuvB core complex component 0.451831
GNAS GNAS complex locus 0.451454
B2M beta-2-microglobulin 0.424765
SPP1 secreted phosphoprotein 1 0.42139
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.401945
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 0.392629
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.386308
SP7 Sp7 transcription factor 0.382223
TLL1 tolloid-like 1 0.374068
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.36704
CASR calcium-sensing receptor 0.361133
IBSP integrin-binding sialoprotein 0.360764
BBX bobby sox homolog (Drosophila) 0.356341
OSCAR osteoclast associated, immunoglobulin-like receptor 0.344574
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.335412
ORAOV1 oral cancer overexpressed 1 0.334315
FAM20A family with sequence similarity 20, member A 0.331756
RUNX2 runt-related transcription factor 2 0.32993
HEBP1 heme binding protein 1 0.328105
BMP2 bone morphogenetic protein 2 0.320817
PPT1 palmitoyl-protein thioesterase 1 0.316456
SDF4 stromal cell derived factor 4 0.31464
SOSTDC1 sclerostin domain containing 1 0.311014
FGF19 fibroblast growth factor 19 0.298011
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.284728
STC1 stanniocalcin 1 0.281153
FGFR1 fibroblast growth factor receptor 1 0.271886
XPO4 exportin 4 0.270108
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.268687
DSPP dentin sialophosphoprotein 0.264785
IL1RAP interleukin 1 receptor accessory protein 0.248203
FURIN furin (paired basic amino acid cleaving enzyme) 0.247501
HSPG2 heparan sulfate proteoglycan 2 0.241546
SSTR1 somatostatin receptor 1 0.238403
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.226952
CALB1 calbindin 1, 28kDa 0.219398
COL1A2 collagen, type I, alpha 2 0.212608
FGF6 fibroblast growth factor 6 0.210925
IGF1 insulin-like growth factor 1 (somatomedin C) 0.201962
MGP matrix Gla protein 0.200982
TIGAR TP53 induced glycolysis regulatory phosphatase 0.187113
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 0.177576
LRP5 low density lipoprotein receptor-related protein 5 0.177301
CTSK cathepsin K 0.158951