osteoporosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis. (Experimental Factor Ontology, EFO_0003882)
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Genes

489 genes co-occuring with the disease osteoporosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
BGLAP bone gamma-carboxyglutamate (gla) protein 3.30818
PTH parathyroid hormone 3.04211
ALPPL2 alkaline phosphatase, placental-like 2 2.77573
ALPL alkaline phosphatase, liver/bone/kidney 2.77512
ALPP alkaline phosphatase, placental 2.77512
CALCA calcitonin-related polypeptide alpha 2.66802
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 2.57109
ESR1 estrogen receptor 1 2.4057
SOST sclerostin 2.37267
CTSK cathepsin K 2.31845
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 2.18818
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 2.15872
RUNX2 runt-related transcription factor 2 2.14942
LRP5 low density lipoprotein receptor-related protein 5 2.09476
IGF1 insulin-like growth factor 1 (somatomedin C) 2.007
BMP2 bone morphogenetic protein 2 1.95864
ACPP acid phosphatase, prostate 1.94219
SP7 Sp7 transcription factor 1.88713
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 1.85137
COL1A1 collagen, type I, alpha 1 1.80021
COL1A2 collagen, type I, alpha 2 1.67955
SLC51A solute carrier family 51, alpha subunit 1.63008
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.58983
CALCR calcitonin receptor 1.57467
ESR2 estrogen receptor 2 (ER beta) 1.54849
LEP leptin 1.48955
SPP1 secreted phosphoprotein 1 1.47638
SHBG sex hormone-binding globulin 1.4421
MGAM maltase-glucoamylase 1.44167
IL6 interleukin 6 1.43639
CASR calcium-sensing receptor 1.36814
PTHLH parathyroid hormone-like hormone 1.3481
FDPS farnesyl diphosphate synthase 1.34243
PTH1R parathyroid hormone 1 receptor 1.28435
LRP6 low density lipoprotein receptor-related protein 6 1.26516
TNF tumor necrosis factor 1.26429
TBX1 T-box 1 1.24689
KL klotho 1.24515
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 1.22518
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.22475
FOS FBJ murine osteosarcoma viral oncogene homolog 1.21998
IBSP integrin-binding sialoprotein 1.19921
TGFB1 transforming growth factor, beta 1 1.18669
GC group-specific component (vitamin D binding protein) 1.14857
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 1.14645
IGFBP3 insulin-like growth factor binding protein 3 1.14433
MRPL49 mitochondrial ribosomal protein L49 1.13628
GCM2 glial cells missing homolog 2 (Drosophila) 1.11309
DCSTAMP dendrocyte expressed seven transmembrane protein 1.11057
ALB albumin 1.10846
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 1.10468
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.09209
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.09167
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 1.08789
INS insulin 1.08286
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 1.07404
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.06312
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.05892
PPARG peroxisome proliferator-activated receptor gamma 1.05429
AR androgen receptor 1.05303
TBCA tubulin folding cofactor A 1.04714
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.02903
ZNF384 zinc finger protein 384 1.02903
ZBTB40 zinc finger and BTB domain containing 40 1.01765
CRP C-reactive protein, pentraxin-related 1.00414
IL1B interleukin 1, beta 0.999924
CTSS cathepsin S 0.983057
POMC proopiomelanocortin 0.982215
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.954525
LCT lactase 0.95369
S100G S100 calcium binding protein G 0.948685
MGP matrix Gla protein 0.948685
FGF23 fibroblast growth factor 23 0.946186
NOG noggin 0.911022
WNT16 wingless-type MMTV integration site family, member 16 0.909787
WNT3A wingless-type MMTV integration site family, member 3A 0.865502
OSCAR osteoclast associated, immunoglobulin-like receptor 0.865502
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.863456
BMP7 bone morphogenetic protein 7 0.862637
THSD7A thrombospondin, type I, domain containing 7A 0.856905
WLS wntless Wnt ligand secretion mediator 0.85404
BMP4 bone morphogenetic protein 4 0.847898
TRPV6 transient receptor potential cation channel, subfamily V, member 6 0.840525
PLEKHO1 pleckstrin homology domain containing, family O member 1 0.818385
WNT10B wingless-type MMTV integration site family, member 10B 0.816334
MEPE matrix extracellular phosphoglycoprotein 0.813052
TRPV5 transient receptor potential cation channel, subfamily V, member 5 0.812232
SFRP1 secreted frizzled-related protein 1 0.812232
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.811001
SEBOX SEBOX homeobox 0.801564
DNAH8 dynein, axonemal, heavy chain 8 0.795411
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.770844
RAP1A RAP1A, member of RAS oncogene family 0.767985
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.762271
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.745578
WRN Werner syndrome, RecQ helicase-like 0.741923
KREMEN2 kringle containing transmembrane protein 2 0.720461
SRR serine racemase 0.714005
JUN jun proto-oncogene 0.713198
GGCX gamma-glutamyl carboxylase 0.706351
AHSG alpha-2-HS-glycoprotein 0.699517
SOX6 SRY (sex determining region Y)-box 6 0.69751
TMEM119 transmembrane protein 119 0.695504
TCF4 transcription factor 4 0.694702
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.691495
ATF4 activating transcription factor 4 0.686691
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.686691
GORAB golgin, RAB6-interacting 0.683892
CCDC170 coiled-coil domain containing 170 0.682693
INSL3 insulin-like 3 (Leydig cell) 0.680697
CA2 carbonic anhydrase II 0.671925
MMP9 matrix metallopeptidase 9 0.66596
PGRMC1 progesterone receptor membrane component 1 0.665563
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.662784
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.661594
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.646953
FRZB frizzled-related protein 0.643009
BMP6 bone morphogenetic protein 6 0.640251
WNT1 wingless-type MMTV integration site family, member 1 0.637495
CSF1R colony stimulating factor 1 receptor 0.62728
CSN1S1 casein alpha s1 0.619051
SIRT1 sirtuin 1 0.613965
IL1RN interleukin 1 receptor antagonist 0.613965
DMRTA1 DMRT-like family A1 0.6003
RXFP2 relaxin/insulin-like family peptide receptor 2 0.597181
MMP13 matrix metallopeptidase 13 0.596012
FABP4 fatty acid binding protein 4, adipocyte 0.587833
ZNF467 zinc finger protein 467 0.587444
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 0.587444
GGPS1 geranylgeranyl diphosphate synthase 1 0.586665
IL11 interleukin 11 0.585887
EGFL6 EGF-like-domain, multiple 6 0.584719
ESRRA estrogen-related receptor alpha 0.583941
IL1A interleukin 1, alpha 0.583941
OSBPL1A oxysterol binding protein-like 1A 0.583552
FGF2 fibroblast growth factor 2 (basic) 0.582384
NELL1 NEL-like 1 (chicken) 0.581217
ALOX15 arachidonate 15-lipoxygenase 0.578494
ADIG adipogenin 0.575383
IAPP islet amyloid polypeptide 0.573439
TMEM135 transmembrane protein 135 0.570718
APOE apolipoprotein E 0.566054
IPP intracisternal A particle-promoted polypeptide 0.565277
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.564112
IGFBP5 insulin-like growth factor binding protein 5 0.564112
SMS spermine synthase 0.562169
CDC14B cell division cycle 14B 0.561004
KY kyphoscoliosis peptidase 0.561004
GPATCH1 G patch domain containing 1 0.561004
CD4 CD4 molecule 0.553239
LPL lipoprotein lipase 0.552851
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.547807
ZNF410 zinc finger protein 410 0.544705
CREB1 cAMP responsive element binding protein 1 0.543155
ZNF446 zinc finger protein 446 0.540055
LOX lysyl oxidase 0.533861
SP1 Sp1 transcription factor 0.528063
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 0.528063
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 0.52536
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.523816
ITGA1 integrin, alpha 1 0.520731
DLX5 distal-less homeobox 5 0.51919
SERHL serine hydrolase-like (pseudogene) 0.51188
THSD4 thrombospondin, type I, domain containing 4 0.504207
HNF4A hepatocyte nuclear factor 4, alpha 0.493885
SOD2 superoxide dismutase 2, mitochondrial 0.493503
SPTBN1 spectrin, beta, non-erythrocytic 1 0.490454
GHRL ghrelin/obestatin prepropeptide 0.486646
NOTCH2 notch 2 0.485505
GPX1 glutathione peroxidase 1 0.482844
NOTCH2NL notch 2 N-terminal like 0.482844
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.482084
KNTC1 kinetochore associated 1 0.481705
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.481325
NOTCH1 notch 1 0.480566
GPR55 G protein-coupled receptor 55 0.477151
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 0.472982
SRP9 signal recognition particle 9kDa 0.472604
SRP9P1 signal recognition particle 9 pseudogene 1 0.472604
EPHA4 EPH receptor A4 0.471089
ACE angiotensin I converting enzyme 0.469954
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.469576
VAV3 vav 3 guanine nucleotide exchange factor 0.467306
FSHR follicle stimulating hormone receptor 0.465416
GPX5 glutathione peroxidase 5 0.465416
GPX4 glutathione peroxidase 4 0.462394
BGN biglycan 0.462016
ZDHHC13 zinc finger, DHHC-type containing 13 0.461639
MAPK8 mitogen-activated protein kinase 8 0.460129
DBT dihydrolipoamide branched chain transacylase E2 0.458241
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 0.456732
NPY neuropeptide Y 0.454093
IL6R interleukin 6 receptor 0.452585
QRFP pyroglutamylated RFamide peptide 0.452585
FOSL1 FOS-like antigen 1 0.449194
CNR1 cannabinoid receptor 1 (brain) 0.448817
CLDN11 claudin 11 0.447311
LEPR leptin receptor 0.442042
WNT5B wingless-type MMTV integration site family, member 5B 0.440538
CD79A CD79a molecule, immunoglobulin-associated alpha 0.438282
DCAF13 DDB1 and CUL4 associated factor 13 0.436402
FN1 fibronectin 1 0.436026
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 0.432646
ZSCAN10 zinc finger and SCAN domain containing 10 0.432646
CRTAP cartilage associated protein 0.431894
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.431894
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.430017
EMP1 epithelial membrane protein 1 0.429642
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.429266
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 0.427015
PRRC2A proline-rich coiled-coil 2A 0.424389
GHR growth hormone receptor 0.424014
KLK3 kallikrein-related peptidase 3 0.422515
JAG1 jagged 1 0.421016
CLCN7 chloride channel, voltage-sensitive 7 0.419892
IL20RA interleukin 20 receptor, alpha 0.418768
PRL prolactin 0.418019
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.417644
WASF2 WAS protein family, member 2 0.416147
LDLR low density lipoprotein receptor 0.413527
SCOC short coiled-coil protein 0.410535
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.410161
RNF185 ring finger protein 185 0.407919
CRH corticotropin releasing hormone 0.404931
SLMO2 slowmo homolog 2 (Drosophila) 0.403064
AXIN2 axin 2 0.398962
OSM oncostatin M 0.398216
PTS 6-pyruvoyltetrahydropterin synthase 0.397471
FAM9B family with sequence similarity 9, member B 0.395235
NF1 neurofibromin 1 0.394118
POSTN periostin, osteoblast specific factor 0.388166
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 0.388166
CER1 cerberus 1, DAN family BMP antagonist 0.387051
CARTPT CART prepropeptide 0.387051
FAM3C family with sequence similarity 3, member C 0.385936
PHEX phosphate regulating endopeptidase homolog, X-linked 0.383337
FST follistatin 0.378885
GGT1 gamma-glutamyltransferase 1 0.377773
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.377031
CST3 cystatin C 0.373328
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.372587
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 0.371847
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.371847
HOPX HOP homeobox 0.371477
FICD FIC domain containing 0.370737
AHR aryl hydrocarbon receptor 0.367779
STARD3NL STARD3 N-terminal like 0.367779
CSK c-src tyrosine kinase 0.36704
TPH1 tryptophan hydroxylase 1 0.364824
PLCL1 phospholipase C-like 1 0.363347
NOS3 nitric oxide synthase 3 (endothelial cell) 0.360395
PDE4A phosphodiesterase 4A, cAMP-specific 0.358551
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) 0.355235
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 0.354131
NPS neuropeptide S 0.350452
TRIM25 tripartite motif containing 25 0.347879
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.346409
OXTR oxytocin receptor 0.346409
GHRH growth hormone releasing hormone 0.346042
OCSTAMP osteoclast stimulatory transmembrane protein 0.34384
DCDC5 doublecortin domain containing 5 0.342372
CDX2 caudal type homeobox 2 0.339073
WIF1 WNT inhibitory factor 1 0.339073
MX1 MX dynamin-like GTPase 1 0.338341
CALB1 calbindin 1, 28kDa 0.337975
CPED1 cadherin-like and PC-esterase domain containing 1 0.337975
IRAK3 interleukin-1 receptor-associated kinase 3 0.337608
OGN osteoglycin 0.336876
IHH indian hedgehog 0.334681
MMP1 matrix metallopeptidase 1 0.333583
MAPK3 mitogen-activated protein kinase 3 0.333218
IL7 interleukin 7 0.333218
SIRT2 sirtuin 2 0.331025
NRM nurim (nuclear envelope membrane protein) 0.328105
PLXNA2 plexin A2 0.32774
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.326646
CFD complement factor D (adipsin) 0.32373
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.323365
FAM131C family with sequence similarity 131, member C 0.322637
KREMEN1 kringle containing transmembrane protein 1 0.321181
SFRP4 secreted frizzled-related protein 4 0.32009
TMEM14A transmembrane protein 14A 0.317909
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 0.317909
SBDS Shwachman-Bodian-Diamond syndrome 0.317545
CBS cystathionine-beta-synthase 0.316092
CA5A carbonic anhydrase VA, mitochondrial 0.315003
WISP3 WNT1 inducible signaling pathway protein 3 0.31464
TGFB2 transforming growth factor, beta 2 0.311377
SMAD4 SMAD family member 4 0.309204
MSX2 msh homeobox 2 0.30848
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.30848
PLS3 plastin 3 0.308118
B2M beta-2-microglobulin 0.306672
PPARA peroxisome proliferator-activated receptor alpha 0.304503
HHIPL2 HHIP-like 2 0.30342
ONECUT3 one cut homeobox 3 0.303059
TMED2 transmembrane emp24 domain trafficking protein 2 0.302698
MSTN myostatin 0.302337
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.298371
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 0.296211
BAX BCL2-associated X protein 0.294772
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 0.294413
UBE2K ubiquitin-conjugating enzyme E2K 0.292257
TXNRD2 thioredoxin reductase 2 0.292257
CAT catalase 0.29118
NUP205 nucleoporin 205kDa 0.290462
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 0.290103
COG2 component of oligomeric golgi complex 2 0.289744
NIPBL Nipped-B homolog (Drosophila) 0.288489
FTL ferritin, light polypeptide 0.286519
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16 0.286519
FTH1 ferritin, heavy polypeptide 1 0.286519
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.285802
DLK2 delta-like 2 homolog (Drosophila) 0.284371
TREML2 triggering receptor expressed on myeloid cells-like 2 0.284371
CA8 carbonic anhydrase VIII 0.283297
SP6 Sp6 transcription factor 0.282225
LMNA lamin A/C 0.280082
UBA5 ubiquitin-like modifier activating enzyme 5 0.27794
ZFYVE1 zinc finger, FYVE domain containing 1 0.277227
IARS isoleucyl-tRNA synthetase 0.277227
MMP2 matrix metallopeptidase 2 0.277227
TSPO translocator protein (18kDa) 0.27687
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.27687
COL2A1 collagen, type II, alpha 1 0.275801
AKAP6 A kinase (PRKA) anchor protein 6 0.274376
DCHS2 dachsous cadherin-related 2 0.274021
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.268332
LTF lactotransferrin 0.266913
VEGFA vascular endothelial growth factor A 0.266203
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.264431
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.264431
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.264077
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 0.263722
IGFBP4 insulin-like growth factor binding protein 4 0.263722
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.263368
C1ORF61 chromosome 1 open reading frame 61 0.260538
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.259477
BMP3 bone morphogenetic protein 3 0.258417
GDF2 growth differentiation factor 2 0.255594
NIPSNAP3B nipsnap homolog 3B (C. elegans) 0.255241
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.253831
HEBP1 heme binding protein 1 0.253479
LAX1 lymphocyte transmembrane adaptor 1 0.253127
SOSTDC1 sclerostin domain containing 1 0.252422
P3H1 prolyl 3-hydroxylase 1 0.251718
ADCY2 adenylate cyclase 2 (brain) 0.251366
MATN2 matrilin 2 0.251015
FAM120A family with sequence similarity 120A 0.251015
ZMPSTE24 zinc metallopeptidase STE24 0.250663
SIRPA signal-regulatory protein alpha 0.250311
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.249608
QPCT glutaminyl-peptide cyclotransferase 0.248905
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.245747
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 0.245396
GATAD2B GATA zinc finger domain containing 2B 0.244345
CA10 carbonic anhydrase X 0.242245
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 0.241895
TYROBP TYRO protein tyrosine kinase binding protein 0.241196
CSF1 colony stimulating factor 1 (macrophage) 0.240497
CA1 carbonic anhydrase I 0.239799
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.233878
DVL2 dishevelled segment polarity protein 2 0.233183
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.231102
HYLS1 hydrolethalus syndrome 1 0.22937
PRDM11 PR domain containing 11 0.229024
ZNF516 zinc finger protein 516 0.229024
PGR progesterone receptor 0.229024
FLNB filamin B, beta 0.228679
C10ORF88 chromosome 10 open reading frame 88 0.227642
GCG glucagon 0.227642
NFYB nuclear transcription factor Y, beta 0.226952
ADGRV1 adhesion G protein-coupled receptor V1 0.225917
TAC1 tachykinin, precursor 1 0.225573
CABIN1 calcineurin binding protein 1 0.22454
GOLGA6B golgin A6 family, member B 0.224196
GOLGA6A golgin A6 family, member A 0.224196
EGFL8 EGF-like-domain, multiple 8 0.223853
PTK2B protein tyrosine kinase 2 beta 0.21974
CTSL cathepsin L 0.21974
TRAM2 translocation associated membrane protein 2 0.219398
PCDH8 protocadherin 8 0.218715
CTF1 cardiotrophin 1 0.218374
SEC24C SEC24 family member C 0.216672
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 0.213959
COMP cartilage oligomeric matrix protein 0.213959
MAB21L2 mab-21-like 2 (C. elegans) 0.213621
IRS2 insulin receptor substrate 2 0.210589
CD47 CD47 molecule 0.209918
PRKCZ protein kinase C, zeta 0.209248
SIRT5 sirtuin 5 0.209248
SIRT4 sirtuin 4 0.208579
FGF1 fibroblast growth factor 1 (acidic) 0.208245
CA3 carbonic anhydrase III 0.208245
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.207245
SQSTM1 sequestosome 1 0.206248
TRPM6 transient receptor potential cation channel, subfamily M, member 6 0.205916
ADM adrenomedullin 0.205254
BMP15 bone morphogenetic protein 15 0.204593
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.204263
MAP3K7CL MAP3K7 C-terminal like 0.20229
SIRT7 sirtuin 7 0.200656
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.199356
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.198064
FBXO15 F-box protein 15 0.198064
SHOX short stature homeobox 0.197742
CTSB cathepsin B 0.196779
GIMAP1 GTPase, IMAP family member 1 0.19582
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1 0.195501
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.191408
TRH thyrotropin-releasing hormone 0.191408
IGFBP1 insulin-like growth factor binding protein 1 0.191408
DPYD dihydropyrimidine dehydrogenase 0.191097
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.190786
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2 0.190168
FUCA1 fucosidase, alpha-L- 1, tissue 0.189859
THNSL2 threonine synthase-like 2 (S. cerevisiae) 0.189244
CNR2 cannabinoid receptor 2 (macrophage) 0.188326
NOVA2 neuro-oncological ventral antigen 2 0.186811
RETN resistin 0.18651
PROS1 protein S (alpha) 0.18651
MMP3 matrix metallopeptidase 3 0.18591
CA7 carbonic anhydrase VII 0.18591
DTNBP1 dystrobrevin binding protein 1 0.18472
GAB2 GRB2-associated binding protein 2 0.18472
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.184424
MBIP MAP3K12 binding inhibitory protein 1 0.183541
WNT4 wingless-type MMTV integration site family, member 4 0.183541
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.183541
CNOT3 CCR4-NOT transcription complex, subunit 3 0.183248
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.182957
IRS1 insulin receptor substrate 1 0.182957
MITF microphthalmia-associated transcription factor 0.182957
ERCC8 excision repair cross-complementation group 8 0.182375
JUNB jun B proto-oncogene 0.182086
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.181798
CA14 carbonic anhydrase XIV 0.181222
DUSP1 dual specificity phosphatase 1 0.180367
COL6A1 collagen, type VI, alpha 1 0.180084
FOXL1 forkhead box L1 0.178682
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.175947
MTL5 metallothionein-like 5, testis-specific (tesmin) 0.173832
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.173832
KMT2A lysine (K)-specific methyltransferase 2A 0.173832
S1PR2 sphingosine-1-phosphate receptor 2 0.173832
NRIP1 nuclear receptor interacting protein 1 0.173571
ITGAV integrin, alpha V 0.173314
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 0.173314
SIK1 salt-inducible kinase 1 0.173057
LEF1 lymphoid enhancer-binding factor 1 0.172291
PRIMA1 proline rich membrane anchor 1 0.171785
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.171535
ALOX5 arachidonate 5-lipoxygenase 0.171286
AKAP11 A kinase (PRKA) anchor protein 11 0.170299
ICAM1 intercellular adhesion molecule 1 0.169812
TRPS1 trichorhinophalangeal syndrome I 0.168381
TOB2 transducer of ERBB2, 2 0.167915
COPG1 coatomer protein complex, subunit gamma 1 0.167452
TGFB3 transforming growth factor, beta 3 0.167452
ARHGAP1 Rho GTPase activating protein 1 0.167224
HRAS Harvey rat sarcoma viral oncogene homolog 0.167224
RNF19B ring finger protein 19B 0.167224
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.167224
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.166995
ANKRD28 ankyrin repeat domain 28 0.166768
FABP3 fatty acid binding protein 3, muscle and heart 0.165874
C6ORF25 chromosome 6 open reading frame 25 0.165655
PCNA proliferating cell nuclear antigen 0.165435
ACVR2A activin A receptor, type IIA 0.164786
TWF1 twinfilin actin binding protein 1 0.164359
SIRT6 sirtuin 6 0.164149
BCL2L1 BCL2-like 1 0.163938
IFNE interferon, epsilon 0.163729
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.163729
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.163317
CCDC34 coiled-coil domain containing 34 0.162707
TSPAN3 tetraspanin 3 0.162707
RAB5C RAB5C, member RAS oncogene family 0.162306
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 0.162306
CAPNS1 calpain, small subunit 1 0.160948
IL20RB interleukin 20 receptor beta 0.160948
CA13 carbonic anhydrase XIII 0.160761
ITPK1 inositol-tetrakisphosphate 1-kinase 0.160387
RPS19BP1 ribosomal protein S19 binding protein 1 0.160203
RBMS3 RNA binding motif, single stranded interacting protein 3 0.160203
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.160021
F3 coagulation factor III (thromboplastin, tissue factor) 0.159838
CCND1 cyclin D1 0.15948
LCK LCK proto-oncogene, Src family tyrosine kinase 0.157929