osteoporosis Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis. (Experimental Factor Ontology, EFO_0003882)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0000939
Similar Terms
Downloads & Tools

Genes

19 genes associated with the osteoporosis phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
NRCAM neuronal cell adhesion molecule 1.1784
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.676552
FTCDNL1 formiminotransferase cyclodeaminase N-terminal like 0.542759
COL4A2 collagen, type IV, alpha 2 0.535899
MECOM MDS1 and EVI1 complex locus 0.522136
RAP1A RAP1A, member of RAS oncogene family 0.522136
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.495598
AKAP6 A kinase (PRKA) anchor protein 6 0.485436
OSBPL1A oxysterol binding protein-like 1A 0.450694
SOX6 SRY (sex determining region Y)-box 6 0.450694
DOK6 docking protein 6 0.426113
TNR tenascin R 0.424465
MCM8 minichromosome maintenance complex component 8 0.417822
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 0.408813
WDFY4 WDFY family member 4 0.407869
TBC1D22A TBC1 domain family, member 22A 0.403739
EEF1DP3 eukaryotic translation elongation factor 1 delta pseudogene 3 0.384893
LIN28B lin-28 homolog B (C. elegans) 0.378074
LRP1B low density lipoprotein receptor-related protein 1B 0.352621