| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the ouabain-2656 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADM | adrenomedullin |
| AKAP9 | A kinase (PRKA) anchor protein 9 |
| AMOTL2 | angiomotin like 2 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ATF3 | activating transcription factor 3 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| AVPI1 | arginine vasopressin-induced 1 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CA4 | carbonic anhydrase IV |
| CD80 | CD80 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon |
| CLK1 | CDC-like kinase 1 |
| CLK4 | CDC-like kinase 4 |
| COL1A1 | collagen, type I, alpha 1 |
| CXORF21 | chromosome X open reading frame 21 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DOK5 | docking protein 5 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| DUX1 | double homeobox 1 |
| EED | embryonic ectoderm development |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| EIF1 | eukaryotic translation initiation factor 1 |
| EPHA2 | EPH receptor A2 |
| ETNK2 | ethanolamine kinase 2 |
| FAM46A | family with sequence similarity 46, member A |
| FLCN | folliculin |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GFER | growth factor, augmenter of liver regeneration |
| GON4L | gon-4-like (C. elegans) |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GTPBP1 | GTP binding protein 1 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H1T | histone cluster 1, H1t |
| HIST2H2BE | histone cluster 2, H2be |
| HOXC13 | homeobox C13 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IL6 | interleukin 6 |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLF6 | Kruppel-like factor 6 |
| KLHL20 | kelch-like family member 20 |
| KLHL24 | kelch-like family member 24 |
| LDLR | low density lipoprotein receptor |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PER1 | period circadian clock 1 |
| PLAC4 | placenta-specific 4 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM48 | RNA binding motif protein 48 |
| RBM5 | RNA binding motif protein 5 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RND3 | Rho family GTPase 3 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RUNX1 | runt-related transcription factor 1 |
| S100A9 | S100 calcium binding protein A9 |
| SERTAD3 | SERTA domain containing 3 |
| SFPQ | splicing factor proline/glutamine-rich |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SKIL | SKI-like proto-oncogene |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC38A2 | solute carrier family 38, member 2 |
| SLN | sarcolipin |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial |
| TBX2 | T-box 2 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TGFB2 | transforming growth factor, beta 2 |
| TXNIP | thioredoxin interacting protein |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZFAND6 | zinc finger, AN1-type domain 6 |
| ZNF143 | zinc finger protein 143 |
| ZNF335 | zinc finger protein 335 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| Symbol | Name |
|---|---|
| ACP6 | acid phosphatase 6, lysophosphatidic |
| ADORA2B | adenosine A2b receptor |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CANT1 | calcium activated nucleotidase 1 |
| CBR3 | carbonyl reductase 3 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHMP7 | charged multivesicular body protein 7 |
| CLDN9 | claudin 9 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| DEAF1 | DEAF1 transcription factor |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DTWD1 | DTW domain containing 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EFTUD1 | elongation factor Tu GTP binding domain containing 1 |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
| ERCC6L | excision repair cross-complementation group 6-like |
| ERO1L | ERO1-like (S. cerevisiae) |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM192A | family with sequence similarity 192, member A |
| FAM50B | family with sequence similarity 50, member B |
| FAM53B | family with sequence similarity 53, member B |
| FANCF | Fanconi anemia, complementation group F |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GLRX2 | glutaredoxin 2 |
| GMIP | GEM interacting protein |
| GPR19 | G protein-coupled receptor 19 |
| H2AFJ | H2A histone family, member J |
| HIRIP3 | HIRA interacting protein 3 |
| HPS5 | Hermansky-Pudlak syndrome 5 |
| ICE2 | interactor of little elongation complex ELL subunit 2 |
| IFRD1 | interferon-related developmental regulator 1 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LIAS | lipoic acid synthetase |
| LRRC8D | leucine rich repeat containing 8 family, member D |
| MAGEH1 | melanoma antigen family H1 |
| MAK16 | MAK16 homolog (S. cerevisiae) |
| MAT2A | methionine adenosyltransferase II, alpha |
| MCRS1 | microspherule protein 1 |
| METTL13 | methyltransferase like 13 |
| MINA | MYC induced nuclear antigen |
| MKKS | McKusick-Kaufman syndrome |
| MNS1 | meiosis-specific nuclear structural 1 |
| MREG | melanoregulin |
| MSX1 | msh homeobox 1 |
| MXD3 | MAX dimerization protein 3 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NELFE | negative elongation factor complex member E |
| NOL8 | nucleolar protein 8 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PALB2 | partner and localizer of BRCA2 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PDCD5 | programmed cell death 5 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POGK | pogo transposable element with KRAB domain |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRMT7 | protein arginine methyltransferase 7 |
| PRR7 | proline rich 7 (synaptic) |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RRP7A | ribosomal RNA processing 7 homolog A (S. cerevisiae) |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SACS | sacsin molecular chaperone |
| SALL2 | spalt-like transcription factor 2 |
| SEH1L | SEH1-like (S. cerevisiae) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| STARD7 | StAR-related lipid transfer (START) domain containing 7 |
| THYN1 | thymocyte nuclear protein 1 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRIM16 | tripartite motif containing 16 |
| TRIM27 | tripartite motif containing 27 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like |
| WDR3 | WD repeat domain 3 |
| XBP1 | X-box binding protein 1 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF184 | zinc finger protein 184 |
| ZNF23 | zinc finger protein 23 |
| ZNF239 | zinc finger protein 239 |
| ZNF250 | zinc finger protein 250 |
| ZNF33B | zinc finger protein 33B |