| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the ouabain-6680 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADM | adrenomedullin |
| AMOTL2 | angiomotin like 2 |
| ARC | activity-regulated cytoskeleton-associated protein |
| AREG | amphiregulin |
| ARL14 | ADP-ribosylation factor-like 14 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATF3 | activating transcription factor 3 |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
| BDNF | brain-derived neurotrophic factor |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CCNL1 | cyclin L1 |
| CD83 | CD83 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLK1 | CDC-like kinase 1 |
| CREB5 | cAMP responsive element binding protein 5 |
| CRY2 | cryptochrome circadian clock 2 |
| CTH | cystathionine gamma-lyase |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| CYTH3 | cytohesin 3 |
| DBF4B | DBF4 zinc finger B |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DLX2 | distal-less homeobox 2 |
| DUSP1 | dual specificity phosphatase 1 |
| EDN1 | endothelin 1 |
| EED | embryonic ectoderm development |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FAM46C | family with sequence similarity 46, member C |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL2 | FOS-like antigen 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GPR87 | G protein-coupled receptor 87 |
| HIC2 | hypermethylated in cancer 2 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H4C | histone cluster 1, H4c |
| HIST1H4D | histone cluster 1, H4d |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| IL33R | interleukin 33 receptor |
| IL6 | interleukin 6 |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KLF6 | Kruppel-like factor 6 |
| KLHL20 | kelch-like family member 20 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MYLIP | myosin regulatory light chain interacting protein |
| MYOZ3 | myozenin 3 |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PSPC1 | paraspeckle component 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| RHOB | ras homolog family member B |
| RND1 | Rho family GTPase 1 |
| RSRC2 | arginine/serine-rich coiled-coil 2 |
| SFPQ | splicing factor proline/glutamine-rich |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SMAD7 | SMAD family member 7 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| STK17B | serine/threonine kinase 17b |
| TEX14 | testis expressed 14 |
| TGFB2 | transforming growth factor, beta 2 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TOB2 | transducer of ERBB2, 2 |
| TPP1 | tripeptidyl peptidase I |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TSC22D2 | TSC22 domain family, member 2 |
| TUFT1 | tuftelin 1 |
| TXNIP | thioredoxin interacting protein |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| YTHDC1 | YTH domain containing 1 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALPK1 | alpha-kinase 1 |
| ANKRD36B | ankyrin repeat domain 36B |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APOL6 | apolipoprotein L, 6 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BEND5 | BEN domain containing 5 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| C3 | complement component 3 |
| CBR3 | carbonyl reductase 3 |
| CBX8 | chromobox homolog 8 |
| CCDC85C | coiled-coil domain containing 85C |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| EFNA3 | ephrin-A3 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EN2 | engrailed homeobox 2 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM120C | family with sequence similarity 120C |
| FANCF | Fanconi anemia, complementation group F |
| FPGT | fucose-1-phosphate guanylyltransferase |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GRAMD1C | GRAM domain containing 1C |
| HMGA2 | high mobility group AT-hook 2 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IFT54 | intraflagellar transport 54 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JRKL | JRK-like |
| KIAA1107 | KIAA1107 |
| KIAA1456 | KIAA1456 |
| KLHL3 | kelch-like family member 3 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LOC100127972 | uncharacterized LOC100127972 |
| LRRC8D | leucine rich repeat containing 8 family, member D |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAGEF1 | melanoma antigen family F1 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MXD3 | MAX dimerization protein 3 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PALB2 | partner and localizer of BRCA2 |
| PDE12 | phosphodiesterase 12 |
| PLD2 | phospholipase D2 |
| POGK | pogo transposable element with KRAB domain |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RBM15B | RNA binding motif protein 15B |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIN2 | Ras and Rab interactor 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| RUFY2 | RUN and FYVE domain containing 2 |
| S100PBP | S100P binding protein |
| SCD5 | stearoyl-CoA desaturase 5 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SEPHS2 | selenophosphate synthetase 2 |
| SETMAR | SET domain and mariner transposase fusion gene |
| SHROOM2 | shroom family member 2 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| STON1 | stonin 1 |
| SYT17 | synaptotagmin XVII |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMSB15A | thymosin beta 15a |
| TTC30A | tetratricopeptide repeat domain 30A |
| WDR25 | WD repeat domain 25 |
| WDR5B | WD repeat domain 5B |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZFP30 | ZFP30 zinc finger protein |
| ZFP69B | ZFP69 zinc finger protein B |
| ZNF239 | zinc finger protein 239 |
| ZNF365 | zinc finger protein 365 |
| ZNF510 | zinc finger protein 510 |
| ZNF606 | zinc finger protein 606 |
| ZNF623 | zinc finger protein 623 |
| ZNF696 | zinc finger protein 696 |