overgrowth Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Excessive postnatal growth which may comprise increased weight, increased length, and/or increased head circumference. (Human Phenotype Ontology, HP_0001548)
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Genes

38 genes co-occuring with the biological term overgrowth in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
AGGF1 angiogenic factor with G patch and FHA domains 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL8 chemokine (C-X-C motif) ligand 8
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EDN1 endothelin 1
EGFR epidermal growth factor receptor
FGF7 fibroblast growth factor 7
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HRAS Harvey rat sarcoma viral oncogene homolog
HSPG2 heparan sulfate proteoglycan 2
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IL15 interleukin 15
IL6 interleukin 6
LEP leptin
LEPR leptin receptor
MAPK14 mitogen-activated protein kinase 14
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
NOG noggin
NPPC natriuretic peptide C
NPR2 natriuretic peptide receptor 2
NSD1 nuclear receptor binding SET domain protein 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PTEN phosphatase and tensin homolog
RNF135 ring finger protein 135
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPRY2 sprouty homolog 2 (Drosophila)
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR4 toll-like receptor 4
TP53 tumor protein p53