oxacillin Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
Description A penicillin antibiotic carrying a 5-methyl-3-phenylisoxazole-4-carboxamide group at position 6. (Chemical Entities of Biological Interest Ontology, CHEBI_7809)
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Genes

11 genes differentially expressed following the oxacillin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
IFNAR1 interferon (alpha, beta and omega) receptor 1 3.69858
ZNF682 zinc finger protein 682 3.16824
ZNF141 zinc finger protein 141 3.08205
RPH3AL rabphilin 3A-like (without C2 domains) 3.07594

decreased expression

Symbol Name Standardized Value
NOS3 nitric oxide synthase 3 (endothelial cell) -3.83592
CCNB2 cyclin B2 -3.32276
EPHB2 EPH receptor B2 -3.2917
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -3.2684
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 -3.23064
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -3.07118
LGALS2 lectin, galactoside-binding, soluble, 2 -3.06714