oxaliplatin Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
Description A platinum coordination entity that has formula C6H14N2.C2O4.Pt. (Chemical Entities of Biological Interest Ontology, CHEBI_31941)
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Genes

623 genes differentially expressed following the oxaliplatin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
HCLS1 hematopoietic cell-specific Lyn substrate 1 6.00708
ALX3 ALX homeobox 3 6.00692
VPS13B vacuolar protein sorting 13 homolog B (yeast) 5.97197
MIR600HG MIR600 host gene 5.92644
GVINP1 GTPase, very large interferon inducible pseudogene 1 5.88069
INTS8 integrator complex subunit 8 5.807
UBE2J1 ubiquitin-conjugating enzyme E2, J1 5.43943
RHOA ras homolog family member A 5.4125
ZNF253 zinc finger protein 253 5.40789
RBM12B RNA binding motif protein 12B 5.40104
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 5.39675
CDYL chromodomain protein, Y-like 5.29168
CNR2 cannabinoid receptor 2 (macrophage) 5.26636
MYO7A myosin VIIA 5.2301
CISH cytokine inducible SH2-containing protein 5.2182
ADRA1D adrenoceptor alpha 1D 5.17691
CACNG5 calcium channel, voltage-dependent, gamma subunit 5 5.1362
CST8 cystatin 8 (cystatin-related epididymal specific) 5.12723
PTDSS1 phosphatidylserine synthase 1 5.04772
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 5.01308
ZNF197 zinc finger protein 197 4.97095
C3ORF36 chromosome 3 open reading frame 36 4.93056
PCDHA2 protocadherin alpha 2 4.90964
SAA3P serum amyloid A3 pseudogene 4.9042
COLGALT1 collagen beta(1-O)galactosyltransferase 1 4.87635
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 4.8692
IL10RA interleukin 10 receptor, alpha 4.86697
CYTL1 cytokine-like 1 4.86525
IKZF4 IKAROS family zinc finger 4 (Eos) 4.79682
CCNE2 cyclin E2 4.77077
RO60 Ro60, Y RNA binding protein 4.75781
PTH2R parathyroid hormone 2 receptor 4.74682
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 4.74434
IGLL1 immunoglobulin lambda-like polypeptide 1 4.67695
SPTA1 spectrin, alpha, erythrocytic 1 4.65362
TBXA2R thromboxane A2 receptor 4.60605
HAO2 hydroxyacid oxidase 2 (long chain) 4.60048
BST2 bone marrow stromal cell antigen 2 4.59602
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 4.59491
PRR14 proline rich 14 4.58993
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.58079
C2ORF83 chromosome 2 open reading frame 83 4.57308
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae) 4.57121
MAPK13 mitogen-activated protein kinase 13 4.51233
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 4.42688
GLI3 GLI family zinc finger 3 4.41012
PSG9 pregnancy specific beta-1-glycoprotein 9 4.40361
PLCL1 phospholipase C-like 1 4.36288
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 4.33824
ZNF224 zinc finger protein 224 4.33585
MAGEA8 melanoma antigen family A8 4.32325
CARD8 caspase recruitment domain family, member 8 4.31132
SNCG synuclein, gamma (breast cancer-specific protein 1) 4.30613
TYMS thymidylate synthetase 4.28355
IRF4 interferon regulatory factor 4 4.27442
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 4.26934
DIO3 deiodinase, iodothyronine, type III 4.23673
MTERF3 mitochondrial transcription termination factor 3 4.2248
MEP1B meprin A, beta 4.21635
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 4.20891
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 4.2083
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 4.20608
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 4.18838
CETN1 centrin, EF-hand protein, 1 4.18072
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 4.17268
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 4.16227
N4BP3 NEDD4 binding protein 3 4.14692
PDX1 pancreatic and duodenal homeobox 1 4.13179
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 4.12726
GRHL2 grainyhead-like 2 (Drosophila) 4.11279
MUC6 mucin 6, oligomeric mucus/gel-forming 4.07544
DLD dihydrolipoamide dehydrogenase 4.04583
PLD1 phospholipase D1, phosphatidylcholine-specific 4.02747
GMEB2 glucocorticoid modulatory element binding protein 2 4.01133
FAM50B family with sequence similarity 50, member B 4.00365
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 3.99146
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 3.97817
KLF7 Kruppel-like factor 7 (ubiquitous) 3.97092
ITFG1 integrin alpha FG-GAP repeat containing 1 3.96934
GIPR gastric inhibitory polypeptide receptor 3.96469
KLKB1 kallikrein B, plasma (Fletcher factor) 1 3.96002
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21 3.95547
HES2 hes family bHLH transcription factor 2 3.95219
GRAP GRB2-related adaptor protein 3.94963
VPREB3 pre-B lymphocyte 3 3.93694
INSRR insulin receptor-related receptor 3.93439
CSNK1D casein kinase 1, delta 3.92954
TSHZ2 teashirt zinc finger homeobox 2 3.92546
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 3.92458
CRYGD crystallin, gamma D 3.92069
CCN3 cellular communication network factor 3 3.91738
NQO1 NAD(P)H dehydrogenase, quinone 1 3.91425
LMAN1L lectin, mannose-binding, 1 like 3.90818
PROZ protein Z, vitamin K-dependent plasma glycoprotein 3.88347
STK3 serine/threonine kinase 3 3.88158
PBX2P1 pre-B-cell leukemia homeobox 2 pseudogene 1 3.87645
GATAD2A GATA zinc finger domain containing 2A 3.87288
MCM4 minichromosome maintenance complex component 4 3.86866
VAV1 vav 1 guanine nucleotide exchange factor 3.86326
SPIDR scaffolding protein involved in DNA repair 3.86291
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 3.83476
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) 3.8326
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 3.82701
MEGF9 multiple EGF-like-domains 9 3.82016
IL4 interleukin 4 3.8194
STK11 serine/threonine kinase 11 3.81731
PGM3 phosphoglucomutase 3 3.80737
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 3.80616
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 3.799
WAS Wiskott-Aldrich syndrome 3.79664
AMBRA1 autophagy/beclin-1 regulator 1 3.7936
ZDHHC6 zinc finger, DHHC-type containing 6 3.78747
ZNF589 zinc finger protein 589 3.77875
MAN1A2 mannosidase, alpha, class 1A, member 2 3.77328
CPOX coproporphyrinogen oxidase 3.77169
PAPOLA poly(A) polymerase alpha 3.76594
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 3.76545
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 3.75654
TREH trehalase (brush-border membrane glycoprotein) 3.75501
RAD21L1 RAD21-like 1 (S. pombe) 3.75405
H1-6 H1.6 linker histone, cluster member 3.74662
MYO16 myosin XVI 3.74631
LUZP4 leucine zipper protein 4 3.74621
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 3.74085
PSG1 pregnancy specific beta-1-glycoprotein 1 3.73432
PRKDC protein kinase, DNA-activated, catalytic polypeptide 3.73091
LY75 lymphocyte antigen 75 3.73016
MSR1 macrophage scavenger receptor 1 3.7246
CCDC57 coiled-coil domain containing 57 3.71717
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 3.70803
RAB40AL RAB40A, member RAS oncogene family-like 3.70141
FBLN2 fibulin 2 3.69808
NR2F6 nuclear receptor subfamily 2, group F, member 6 3.6878
CEP43 centrosomal protein 43 3.68325
KIF11 kinesin family member 11 3.68195
CD53 CD53 molecule 3.68136
HAMP hepcidin antimicrobial peptide 3.67963
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 3.67399
SDHAP1 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 3.67109
ZNF702P zinc finger protein 702, pseudogene 3.66153
SRCAP Snf2-related CREBBP activator protein 3.64892
ECE2 endothelin converting enzyme 2 3.6444
SNCA synuclein, alpha (non A4 component of amyloid precursor) 3.64235
FH fumarate hydratase 3.64018
CEP295 centrosomal protein 295kDa 3.63232
GPATCH8 G patch domain containing 8 3.62935
TREM2 triggering receptor expressed on myeloid cells 2 3.62641
GCM1 glial cells missing homolog 1 (Drosophila) 3.62591
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 3.62304
CTBP1 C-terminal binding protein 1 3.62266
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 3.62253
ARID4B AT rich interactive domain 4B (RBP1-like) 3.61816
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 3.60288
ZNF506 zinc finger protein 506 3.60177
KDM8 lysine (K)-specific demethylase 8 3.5973
STS steroid sulfatase (microsomal), isozyme S 3.59664
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 3.593
CCN5 cellular communication network factor 5 3.59054
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 3.57578
IKZF1 IKAROS family zinc finger 1 (Ikaros) 3.57464
NCKAP1L NCK-associated protein 1-like 3.57388
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 3.5698
LGSN lengsin, lens protein with glutamine synthetase domain 3.54992
CHMP7 charged multivesicular body protein 7 3.54052
OR7A5 olfactory receptor, family 7, subfamily A, member 5 3.53632
HPX hemopexin 3.53391
RPS20 ribosomal protein S20 3.52673
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 3.52672
MAEA macrophage erythroblast attacher 3.52236
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 3.52043
TRIM10 tripartite motif containing 10 3.52031
ETHE1 ethylmalonic encephalopathy 1 3.51503
DENND6B DENN/MADD domain containing 6B 3.50472
SYT1 synaptotagmin I 3.50306
RALB v-ral simian leukemia viral oncogene homolog B 3.5016
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 3.4984
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 3.49614
SLCO2B1 solute carrier organic anion transporter family, member 2B1 3.49312
CD72 CD72 molecule 3.49189
PDS5A PDS5 cohesin associated factor A 3.4916
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) 3.48563
RNF24 ring finger protein 24 3.48403
INHA inhibin, alpha 3.48331
OR1A1 olfactory receptor, family 1, subfamily A, member 1 3.46289
POU2AF1 POU class 2 associating factor 1 3.45951
TOR4A torsin family 4, member A 3.457
NIPAL2 NIPA-like domain containing 2 3.45068
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 3.44365
LXN latexin 3.44283
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 3.43981
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 3.43485
FGB fibrinogen beta chain 3.42401
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 3.4123
LOC730101 uncharacterized LOC730101 3.41164
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 3.40979
PRY PTPN13-like, Y-linked 3.40569
FSTL4 follistatin-like 4 3.40428
INHBC inhibin, beta C 3.40341
MT1H metallothionein 1H 3.40331
ALDOB aldolase B, fructose-bisphosphate 3.40069
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 3.39427
MT1E metallothionein 1E 3.39254
BTG2 BTG family, member 2 3.38953
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.38666
FCRL2 Fc receptor-like 2 3.3866
ANK1 ankyrin 1, erythrocytic 3.38647
ITGA9 integrin, alpha 9 3.38038
ZNF154 zinc finger protein 154 3.36644
NHLRC2 NHL repeat containing 2 3.3634
HOXB7 homeobox B7 3.35848
RPL17 ribosomal protein L17 3.35845
TSPAN14 tetraspanin 14 3.3567
BORCS6 BLOC-1 related complex subunit 6 3.3559
PNMT phenylethanolamine N-methyltransferase 3.34179
RHOF ras homolog family member F (in filopodia) 3.34131
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 3.34063
IQSEC1 IQ motif and Sec7 domain 1 3.33824
TAS2R7 taste receptor, type 2, member 7 3.33494
CYBRD1 cytochrome b reductase 1 3.33477
IKZF2 IKAROS family zinc finger 2 (Helios) 3.32991
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 3.32732
C1ORF56 chromosome 1 open reading frame 56 3.31741
FANCA Fanconi anemia, complementation group A 3.31532
CD84 CD84 molecule 3.31252
ZNF652 zinc finger protein 652 3.31106
TRPS1 trichorhinophalangeal syndrome I 3.31047
KEL Kell blood group, metallo-endopeptidase 3.30867
SDC3 syndecan 3 3.30719
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 3.30397
GUSB glucuronidase, beta 3.30367
FBXL14 F-box and leucine-rich repeat protein 14 3.30331
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 3.29902
ZCCHC4 zinc finger, CCHC domain containing 4 3.28834
F11 coagulation factor XI 3.28535
BTK Bruton agammaglobulinemia tyrosine kinase 3.28141
IGSF9B immunoglobulin superfamily, member 9B 3.27111
E2F8 E2F transcription factor 8 3.26702
RAG2 recombination activating gene 2 3.2664
EPN3 epsin 3 3.26519
ZNF835 zinc finger protein 835 3.25674
GYPA glycophorin A (MNS blood group) 3.24996
LINC02249 long intergenic non-protein coding RNA 2249 3.24551
DCLRE1B DNA cross-link repair 1B 3.24437
COLEC11 collectin sub-family member 11 3.23994
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae) 3.23444
FAM124B family with sequence similarity 124B 3.23139
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 3.23086
TBX4 T-box 4 3.22662
ADGRE2 adhesion G protein-coupled receptor E2 3.22602
MT1F metallothionein 1F 3.22293
ZNF706 zinc finger protein 706 3.21893
CRLF2 cytokine receptor-like factor 2 3.21811
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 3.21336
G6PC1 glucose-6-phosphatase catalytic subunit 1 3.20988
RPL38 ribosomal protein L38 3.20671
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 3.19293
MCTP2 multiple C2 domains, transmembrane 2 3.19195
NSD3 nuclear receptor binding SET domain protein 3 3.19183
MATN2 matrilin 2 3.19118
PSD4 pleckstrin and Sec7 domain containing 4 3.1846
RPL37 ribosomal protein L37 3.18382
SZRD1 SUZ RNA binding domain containing 1 3.18003
MAN2B2 mannosidase, alpha, class 2B, member 2 3.1799
CDCA4 cell division cycle associated 4 3.17244
METTL18 methyltransferase like 18 3.16363
PCNA proliferating cell nuclear antigen 3.15653
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 3.15601
MT1X metallothionein 1X 3.15149
OSGIN2 oxidative stress induced growth inhibitor family member 2 3.14908
C1QB complement component 1, q subcomponent, B chain 3.14826
MTERF4 mitochondrial transcription termination factor 4 3.14824
LAPTM5 lysosomal protein transmembrane 5 3.14819
EHF ets homologous factor 3.1464
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 3.14578
CNGB1 cyclic nucleotide gated channel beta 1 3.14539
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 3.13433
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 3.13101
RBM41 RNA binding motif protein 41 3.13085
ZSCAN9 zinc finger and SCAN domain containing 9 3.12548
EXTL3 exostosin-like glycosyltransferase 3 3.1211
SLC30A1 solute carrier family 30 (zinc transporter), member 1 3.12048
ACAA1 acetyl-CoA acyltransferase 1 3.11246
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 3.11139
PKLR pyruvate kinase, liver and RBC 3.10771
SSPN sarcospan 3.10438
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 3.09816
FTCD formimidoyltransferase cyclodeaminase 3.09755
ANGPTL2 angiopoietin-like 2 3.09682
GINS1 GINS complex subunit 1 (Psf1 homolog) 3.09282
NEUROD2 neuronal differentiation 2 3.08784
KIAA0319 KIAA0319 3.08737
LAMP1 lysosomal-associated membrane protein 1 3.08463
PRDM2 PR domain containing 2, with ZNF domain 3.08337
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 3.08331
GRWD1 glutamate-rich WD repeat containing 1 3.07857
HES1 hes family bHLH transcription factor 1 3.07836
LHFPL2 lipoma HMGIC fusion partner-like 2 3.07595
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 3.06423
USP48 ubiquitin specific peptidase 48 3.06215
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) 3.06086
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 3.06085
SIRT7 sirtuin 7 3.05944
ARHGAP25 Rho GTPase activating protein 25 3.05572
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 3.05267
IL4R interleukin 4 receptor 3.04972
RAG1 recombination activating gene 1 3.04816
LGALS9 lectin, galactoside-binding, soluble, 9 3.04804
ERCC4 excision repair cross-complementation group 4 3.04598
PGAP3 post-GPI attachment to proteins 3 3.0457
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 3.04224
GRM6 glutamate receptor, metabotropic 6 3.04041
GRIA3 glutamate receptor, ionotropic, AMPA 3 3.03953
EXT1 exostosin glycosyltransferase 1 3.03541
MARCHF3 membrane associated ring-CH-type finger 3 3.03266
GLRX5 glutaredoxin 5 3.0312
EGFR epidermal growth factor receptor 3.0307
R3HDM1 R3H domain containing 1 3.02907
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 3.0251
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 3.02356
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 3.02145
NVL nuclear VCP-like 3.0209
SPHK2 sphingosine kinase 2 3.01962
HMHB1 histocompatibility (minor) HB-1 3.01905
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 3.01824
AK5 adenylate kinase 5 3.01641
H2BC13 H2B clustered histone 13 3.01549
RAD50 RAD50 homolog (S. cerevisiae) 3.01494
CDC42SE1 CDC42 small effector 1 3.01491
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 3.01473
ADAM17 ADAM metallopeptidase domain 17 3.00728
PGM5 phosphoglucomutase 5 3.00655
CFB complement factor B 3.00584
DCTPP1 dCTP pyrophosphatase 1 3.00467
RBM17 RNA binding motif protein 17 3.00444
IFNAR1 interferon (alpha, beta and omega) receptor 1 3.00356

decreased expression

Symbol Name Standardized Value
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta -8.64072
GSTZ1 glutathione S-transferase zeta 1 -7.2312
NNT nicotinamide nucleotide transhydrogenase -6.44774
LIN7A lin-7 homolog A (C. elegans) -6.20967
PKP1 plakophilin 1 -5.37074
GRK4 G protein-coupled receptor kinase 4 -5.34468
KRT84 keratin 84, type II -5.30662
DZIP3 DAZ interacting zinc finger protein 3 -5.27541
PDLIM5 PDZ and LIM domain 5 -5.14751
DERA deoxyribose-phosphate aldolase (putative) -5.06498
DPPA4 developmental pluripotency associated 4 -5.06414
CEP57 centrosomal protein 57kDa -5.01277
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -4.98441
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) -4.9799
CEP68 centrosomal protein 68kDa -4.93973
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 -4.93787
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -4.85992
PCYT1B phosphate cytidylyltransferase 1, choline, beta -4.85653
RBM4 RNA binding motif protein 4 -4.82398
PLSCR1 phospholipid scramblase 1 -4.79213
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 -4.78095
PLLP plasmolipin -4.77341
BFAR bifunctional apoptosis regulator -4.76962
IL32 interleukin 32 -4.6713
ZC2HC1C zinc finger, C2HC-type containing 1C -4.66939
SRR serine racemase -4.64786
AMZ2 archaelysin family metallopeptidase 2 -4.641
MTMR2 myotubularin related protein 2 -4.62368
HKDC1 hexokinase domain containing 1 -4.60955
HNMT histamine N-methyltransferase -4.56398
FKRP fukutin related protein -4.5508
RABGAP1 RAB GTPase activating protein 1 -4.51709
GK3 glycerol kinase 3 -4.51631
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) -4.49467
TEX10 testis expressed 10 -4.48205
ZNF3 zinc finger protein 3 -4.47769
SKIL SKI-like proto-oncogene -4.46349
NLRP1 NLR family, pyrin domain containing 1 -4.38279
RNF130 ring finger protein 130 -4.37145
PLPPR1 phospholipid phosphatase related 1 -4.35434
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -4.32596
CCDC198 coiled-coil domain containing 198 -4.31517
BICD2 bicaudal D homolog 2 (Drosophila) -4.29586
FGFR3 fibroblast growth factor receptor 3 -4.29441
TPPP3 tubulin polymerization-promoting protein family member 3 -4.28695
ITGA7 integrin, alpha 7 -4.28293
RAB21 RAB21, member RAS oncogene family -4.27927
TCAF1 TRPM8 channel-associated factor 1 -4.26671
RPA4 replication protein A4, 30kDa -4.25395
USP16 ubiquitin specific peptidase 16 -4.23427
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -4.22099
TMEM47 transmembrane protein 47 -4.21652
STAG2 stromal antigen 2 -4.2081
SPTAN1 spectrin, alpha, non-erythrocytic 1 -4.19765
CRYBG2 crystallin beta-gamma domain containing 2 -4.19554
EML4 echinoderm microtubule associated protein like 4 -4.19171
BTF3P11 basic transcription factor 3 pseudogene 11 -4.18479
TACC2 transforming, acidic coiled-coil containing protein 2 -4.17523
H2AZ2 H2A.Z variant histone 2 -4.16649
DNAH17 dynein, axonemal, heavy chain 17 -4.15553
FOXN3 forkhead box N3 -4.15459
MPPED2 metallophosphoesterase domain containing 2 -4.14352
HCCS holocytochrome c synthase -4.14202
ANXA5 annexin A5 -4.13113
RCAN3 RCAN family member 3 -4.11525
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -4.10483
KLRC3 killer cell lectin-like receptor subfamily C, member 3 -4.09819
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -4.08765
LST1 leukocyte specific transcript 1 -4.0849
SGK1 serum/glucocorticoid regulated kinase 1 -4.06157
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) -4.05722
TMEM134 transmembrane protein 134 -4.04051
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) -4.0365
QKI QKI, KH domain containing, RNA binding -4.02725
RAB32 RAB32, member RAS oncogene family -4.02523
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -4.01371
MYF6 myogenic factor 6 (herculin) -4.01325
TEKT2 tektin 2 (testicular) -3.99802
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -3.9961
WDFY3 WD repeat and FYVE domain containing 3 -3.99578
MAP2K4 mitogen-activated protein kinase kinase 4 -3.99463
CCDC90B coiled-coil domain containing 90B -3.97964
BIRC2 baculoviral IAP repeat containing 2 -3.96625
SESN1 sestrin 1 -3.94945
MYH7 myosin, heavy chain 7, cardiac muscle, beta -3.94297
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta -3.94071
COMMD9 COMM domain containing 9 -3.93701
TBP TATA box binding protein -3.93492
KRT76 keratin 76, type II -3.91138
MYH2 myosin, heavy chain 2, skeletal muscle, adult -3.90778
PLBD1 phospholipase B domain containing 1 -3.89537
HDAC6 histone deacetylase 6 -3.89007
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -3.87438
PFDN2 prefoldin subunit 2 -3.86923
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -3.86686
ENO3 enolase 3 (beta, muscle) -3.86459
USP11 ubiquitin specific peptidase 11 -3.85019
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.85006
SYNGR3 synaptogyrin 3 -3.84588
ETV1 ets variant 1 -3.82733
SMCO4 single-pass membrane protein with coiled-coil domains 4 -3.82429
PTPN21 protein tyrosine phosphatase, non-receptor type 21 -3.82041
RBMS1 RNA binding motif, single stranded interacting protein 1 -3.81649
TCP11L1 t-complex 11, testis-specific-like 1 -3.80026
DIPK1A divergent protein kinase domain 1A -3.79727
NOD2 nucleotide-binding oligomerization domain containing 2 -3.77988
PRKN parkin RBR E3 ubiquitin protein ligase -3.77784
LGALS2 lectin, galactoside-binding, soluble, 2 -3.77631
STXBP6 syntaxin binding protein 6 (amisyn) -3.77313
MAP7D1 MAP7 domain containing 1 -3.75806
MCUR1 mitochondrial calcium uniporter regulator 1 -3.75094
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -3.75073
AUTS2 autism susceptibility candidate 2 -3.74992
MATN3 matrilin 3 -3.74741
KLRG1 killer cell lectin-like receptor subfamily G, member 1 -3.73672
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -3.72904
ZNF106 zinc finger protein 106 -3.72671
FHL1 four and a half LIM domains 1 -3.72415
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 -3.7239
C4ORF19 chromosome 4 open reading frame 19 -3.71759
IVD isovaleryl-CoA dehydrogenase -3.7157
AKAP1 A kinase (PRKA) anchor protein 1 -3.71311
GAL3ST1 galactose-3-O-sulfotransferase 1 -3.70855
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -3.7051
PQBP1 polyglutamine binding protein 1 -3.68968
DIAPH2 diaphanous-related formin 2 -3.68127
CAMK1 calcium/calmodulin-dependent protein kinase I -3.67728
CAMTA1 calmodulin binding transcription activator 1 -3.67522
RNF32 ring finger protein 32 -3.67206
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -3.67
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -3.66802
PLAAT3 phospholipase A and acyltransferase 3 -3.66213
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase -3.66095
ARSL arylsulfatase L -3.65788
SEC11A SEC11 homolog A (S. cerevisiae) -3.65452
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -3.64211
CD2 CD2 molecule -3.63767
KRCC1 lysine-rich coiled-coil 1 -3.63592
PITX2 paired-like homeodomain 2 -3.62718
UBXN1 UBX domain protein 1 -3.61909
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 -3.6085
MRPL11 mitochondrial ribosomal protein L11 -3.6044
GLI2 GLI family zinc finger 2 -3.59334
UTF1 undifferentiated embryonic cell transcription factor 1 -3.58126
TBX2 T-box 2 -3.57264
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -3.57069
LMO7 LIM domain 7 -3.57041
MYG1 MYG1 exonuclease -3.56858
CASP4 caspase 4, apoptosis-related cysteine peptidase -3.5642
DOP1A DOP1 leucine zipper like protein A -3.5598
CD3D CD3d molecule, delta (CD3-TCR complex) -3.55084
CAAP1 caspase activity and apoptosis inhibitor 1 -3.55068
RBPJ recombination signal binding protein for immunoglobulin kappa J region -3.54588
NKX2-2 NK2 homeobox 2 -3.54515
PLAA phospholipase A2-activating protein -3.54467
EFNA1 ephrin-A1 -3.52411
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -3.50913
NANOG Nanog homeobox -3.5064
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 -3.50519
MOCS2 molybdenum cofactor synthesis 2 -3.50429
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -3.49348
LRRC49 leucine rich repeat containing 49 -3.47745
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 -3.46
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 -3.45346
KLF4 Kruppel-like factor 4 (gut) -3.44955
PGD phosphogluconate dehydrogenase -3.44044
COQ8A coenzyme Q8A -3.42135
SEPTIN10 septin 10 -3.41769
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -3.4163
ZNF263 zinc finger protein 263 -3.41535
RPUSD2 RNA pseudouridylate synthase domain containing 2 -3.41184
URGCP upregulator of cell proliferation -3.41128
DOK2 docking protein 2, 56kDa -3.40949
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 -3.40699
CAMKMT calmodulin-lysine N-methyltransferase -3.40237
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) -3.40103
AOPEP aminopeptidase O (putative) -3.39858
JAM3 junctional adhesion molecule 3 -3.3954
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.39064
EVPL envoplakin -3.3844
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 -3.37329
GPR6 G protein-coupled receptor 6 -3.37062
NEK9 NIMA-related kinase 9 -3.35674
C2ORF27A chromosome 2 open reading frame 27A -3.3558
ECI1 enoyl-CoA delta isomerase 1 -3.3368
DMTF1 cyclin D binding myb-like transcription factor 1 -3.33529
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -3.33468
C11ORF24 chromosome 11 open reading frame 24 -3.31266
PTPRG protein tyrosine phosphatase, receptor type, G -3.31164
NMT2 N-myristoyltransferase 2 -3.31014
FCGRT Fc fragment of IgG, receptor, transporter, alpha -3.30928
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -3.30628
CPVL carboxypeptidase, vitellogenic-like -3.30457
BACE1 beta-site APP-cleaving enzyme 1 -3.30091
MID1 midline 1 -3.30019
MTNR1A melatonin receptor 1A -3.29997
MYOZ2 myozenin 2 -3.29632
FAIM Fas apoptotic inhibitory molecule -3.2936
ASGR1 asialoglycoprotein receptor 1 -3.29089
CLNS1A chloride channel, nucleotide-sensitive, 1A -3.28829
NGDN neuroguidin, EIF4E binding protein -3.28613
ZNF281 zinc finger protein 281 -3.28577
PAAF1 proteasomal ATPase-associated factor 1 -3.27831
KLHL41 kelch-like family member 41 -3.26957
YAP1 Yes-associated protein 1 -3.26665
OLIG2 oligodendrocyte lineage transcription factor 2 -3.25788
VEGFB vascular endothelial growth factor B -3.25642
NANS N-acetylneuraminic acid synthase -3.25406
IL6ST interleukin 6 signal transducer -3.25305
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -3.25274
NDFIP1 Nedd4 family interacting protein 1 -3.24778
MYLK myosin light chain kinase -3.24287
POU5F1B POU class 5 homeobox 1B -3.24131
TTC23 tetratricopeptide repeat domain 23 -3.24048
VDAC1 voltage-dependent anion channel 1 -3.23766
DSG1 desmoglein 1 -3.23507
TMEM258 transmembrane protein 258 -3.23356
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -3.23289
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -3.22204
PYGM phosphorylase, glycogen, muscle -3.22181
CDC14B cell division cycle 14B -3.22011
EGR2 early growth response 2 -3.2098
CYCS cytochrome c, somatic -3.20429
CGREF1 cell growth regulator with EF-hand domain 1 -3.1877
MIS18A MIS18 kinetochore protein A -3.18541
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -3.1843
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 -3.17691
THAP10 THAP domain containing 10 -3.1755
OPTN optineurin -3.1747
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 -3.17237
RFX1 regulatory factor X, 1 (influences HLA class II expression) -3.16578
RADX RPA1 related single stranded DNA binding protein, X-linked -3.16542
ACTA1 actin, alpha 1, skeletal muscle -3.15757
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -3.15392
GLRB glycine receptor, beta -3.14873
CENPT centromere protein T -3.14765
WASHC3 WASH complex subunit 3 -3.1448
SPTBN2 spectrin, beta, non-erythrocytic 2 -3.13968
TPM3 tropomyosin 3 -3.139
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -3.13799
SH2D1A SH2 domain containing 1A -3.13476
AARSD1 alanyl-tRNA synthetase domain containing 1 -3.13124
HUS1 HUS1 checkpoint homolog (S. pombe) -3.13079
ADGRL2 adhesion G protein-coupled receptor L2 -3.13038
CXADR coxsackie virus and adenovirus receptor -3.12952
CCNL2 cyclin L2 -3.12579
F3 coagulation factor III (thromboplastin, tissue factor) -3.1153
PLPP1 phospholipid phosphatase 1 -3.11292
NRAP nebulin-related anchoring protein -3.10963
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 -3.10884
DLL3 delta-like 3 (Drosophila) -3.10638
MOG myelin oligodendrocyte glycoprotein -3.10163
ARHGAP22 Rho GTPase activating protein 22 -3.09868
RAP1B RAP1B, member of RAS oncogene family -3.09864
TMEM38B transmembrane protein 38B -3.09692
KLF6 Kruppel-like factor 6 -3.09398
FZD1 frizzled class receptor 1 -3.0885
TNNC1 troponin C type 1 (slow) -3.08529
EGR4 early growth response 4 -3.08406
PRUNE1 prune exopolyphosphatase 1 -3.084
CTNNBIP1 catenin, beta interacting protein 1 -3.08384
KRT14 keratin 14, type I -3.08013
DMD dystrophin -3.08007
ARHGAP28 Rho GTPase activating protein 28 -3.07521
DHRS2 dehydrogenase/reductase (SDR family) member 2 -3.07188
STK17A serine/threonine kinase 17a -3.07011
CCT2 chaperonin containing TCP1, subunit 2 (beta) -3.0678
AXIN1 axin 1 -3.06488
NOP10 NOP10 ribonucleoprotein -3.06358
CST3 cystatin C -3.0604
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 -3.05045
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -3.04834
ACADL acyl-CoA dehydrogenase, long chain -3.04827
EFCAB2 EF-hand calcium binding domain 2 -3.04555
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -3.04358
DOCK6 dedicator of cytokinesis 6 -3.03635
RPS14P3 ribosomal protein S14 pseudogene 3 -3.03435
CX3CL1 chemokine (C-X3-C motif) ligand 1 -3.03217
IL1RN interleukin 1 receptor antagonist -3.03086
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) -3.03051
OASL 2'-5'-oligoadenylate synthetase-like -3.0262
GARS1 glycyl-tRNA synthetase 1 -3.02035
ZNF711 zinc finger protein 711 -3.01805
CTNNBL1 catenin, beta like 1 -3.01481
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) -3.01383
FGF14 fibroblast growth factor 14 -3.01328
EIF3F eukaryotic translation initiation factor 3, subunit F -3.01039
SCLY selenocysteine lyase -3.00912