oxamniquine-2924 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the oxamniquine-2924 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACACB acetyl-CoA carboxylase beta
ADAM22 ADAM metallopeptidase domain 22
ADORA1 adenosine A1 receptor
AGRN agrin
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALOX12 arachidonate 12-lipoxygenase
AMN amnion associated transmembrane protein
AMPD3 adenosine monophosphate deaminase 3
ATP13A2 ATPase type 13A2
BTBD18 BTB (POZ) domain containing 18
C1ORF61 chromosome 1 open reading frame 61
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAV2 caveolin 2
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD59 CD59 molecule, complement regulatory protein
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK20 cyclin-dependent kinase 20
CEP170B centrosomal protein 170B
COL10A1 collagen, type X, alpha 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DRD5 dopamine receptor D5
EFNB3 ephrin-B3
ENG endoglin
EPN1 epsin 1
ESR1 estrogen receptor 1
ETV7 ets variant 7
EXPH5 exophilin 5
FAM46C family with sequence similarity 46, member C
FAM86C1 family with sequence similarity 86, member C1
FKRP fukutin related protein
FOXO1 forkhead box O1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAS8 growth arrest-specific 8
GSN gelsolin
GTDC1 glycosyltransferase-like domain containing 1
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HMOX2 heme oxygenase 2
HOXB6 homeobox B6
HPD 4-hydroxyphenylpyruvate dioxygenase
IGFBP5 insulin-like growth factor binding protein 5
IL12RB1 interleukin 12 receptor, beta 1
IL17RC interleukin 17 receptor C
INO80D INO80 complex subunit D
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAM2 junctional adhesion molecule 2
KAZN kazrin, periplakin interacting protein
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAD1 ladinin 1
LAMA2 laminin, alpha 2
LTC4S leukotriene C4 synthase
MAGEA6 melanoma antigen family A6
MAPK11 mitogen-activated protein kinase 11
MAPT microtubule-associated protein tau
MARC2 mitochondrial amidoxime reducing component 2
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MORN1 MORN repeat containing 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NIN ninein (GSK3B interacting protein)
NOD2 nucleotide-binding oligomerization domain containing 2
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PARVB parvin, beta
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKDREJ polycystin (PKD) family receptor for egg jelly
PLEKHS1 pleckstrin homology domain containing, family S member 1
PML promyelocytic leukemia
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRKCA protein kinase C, alpha
RAB40AL RAB40A, member RAS oncogene family-like
RUNX1 runt-related transcription factor 1
SAMD4A sterile alpha motif domain containing 4A
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEPP1 selenoprotein P, plasma, 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SH2D2A SH2 domain containing 2A
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC12A8 solute carrier family 12, member 8
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SOCS3 suppressor of cytokine signaling 3
SP4 Sp4 transcription factor
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTB spectrin, beta, erythrocytic
SULT4A1 sulfotransferase family 4A, member 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SZT2 seizure threshold 2 homolog (mouse)
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TCP11L1 t-complex 11, testis-specific-like 1
TMEM212 transmembrane protein 212
TMLHE trimethyllysine hydroxylase, epsilon
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TTC22 tetratricopeptide repeat domain 22
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VPS9D1 VPS9 domain containing 1
WDTC1 WD and tetratricopeptide repeats 1
ZER1 zyg-11 related, cell cycle regulator
ZFPL1 zinc finger protein-like 1
ZNF574 zinc finger protein 574

decreased expression

Symbol Name
AGO3 argonaute RISC catalytic component 3
AKTIP AKT interacting protein
APH1B APH1B gamma secretase subunit
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BAHD1 bromo adjacent homology domain containing 1
BAK1 BCL2-antagonist/killer 1
BATF basic leucine zipper transcription factor, ATF-like
C3 complement component 3
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCDC109B coiled-coil domain containing 109B
CCDC25 coiled-coil domain containing 25
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CISH cytokine inducible SH2-containing protein
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CSRNP2 cysteine-serine-rich nuclear protein 2
CST3 cystatin C
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYSF dysferlin
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERCC6 excision repair cross-complementation group 6
FAM127A family with sequence similarity 127, member A
FES FES proto-oncogene, tyrosine kinase
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GBAS glioblastoma amplified sequence
GEM GTP binding protein overexpressed in skeletal muscle
GIN1 gypsy retrotransposon integrase 1
GSTZ1 glutathione S-transferase zeta 1
GUSBP3 glucuronidase, beta pseudogene 3
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGBP1 immunoglobulin (CD79A) binding protein 1
IGSF6 immunoglobulin superfamily, member 6
INPP1 inositol polyphosphate-1-phosphatase
IQGAP2 IQ motif containing GTPase activating protein 2
KIF13B kinesin family member 13B
L2HGDH L-2-hydroxyglutarate dehydrogenase
LINC00115 long intergenic non-protein coding RNA 115
MED24 mediator complex subunit 24
MICA MHC class I polypeptide-related sequence A
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MRPL52 mitochondrial ribosomal protein L52
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MX1 MX dynamin-like GTPase 1
MXD3 MAX dimerization protein 3
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NHEJ1 nonhomologous end-joining factor 1
OTUD3 OTU deubiquitinase 3
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PDZD7 PDZ domain containing 7
PECR peroxisomal trans-2-enoyl-CoA reductase
PGPEP1 pyroglutamyl-peptidase I
PHGDH phosphoglycerate dehydrogenase
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PMCH pro-melanin-concentrating hormone
POMT1 protein-O-mannosyltransferase 1
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PTX3 pentraxin 3, long
QTRT1 queuine tRNA-ribosyltransferase 1
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RBM7 RNA binding motif protein 7
RNF130 ring finger protein 130
RPL13P5 ribosomal protein L13 pseudogene 5
RWDD2A RWD domain containing 2A
SECISBP2 SECIS binding protein 2
SGMS1 sphingomyelin synthase 1
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC38A6 solute carrier family 38, member 6
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
STX1A syntaxin 1A (brain)
TESK1 testis-specific kinase 1
THAP10 THAP domain containing 10
THOP1 thimet oligopeptidase 1
TMEM104 transmembrane protein 104
TMEM156 transmembrane protein 156
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNNT1 troponin T type 1 (skeletal, slow)
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAIP TRAF interacting protein
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TXNDC15 thioredoxin domain containing 15
UPP1 uridine phosphorylase 1
VCPKMT valosin containing protein lysine (K) methyltransferase
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR46 WD repeat domain 46
ZMYM1 zinc finger, MYM-type 1
ZNF280D zinc finger protein 280D
ZNF468 zinc finger protein 468
ZNF573 zinc finger protein 573
ZNF770 zinc finger protein 770
ZNF813 zinc finger protein 813