oxamniquine-4006 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the oxamniquine-4006 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ADAM23 ADAM metallopeptidase domain 23
ASPN asporin
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BATF basic leucine zipper transcription factor, ATF-like
BBC3 BCL2 binding component 3
BEND5 BEN domain containing 5
BMP7 bone morphogenetic protein 7
C1ORF54 chromosome 1 open reading frame 54
CAMP cathelicidin antimicrobial peptide
CCR2 chemokine (C-C motif) receptor 2
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK13 cyclin-dependent kinase 13
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIDEC cell death-inducing DFFA-like effector c
CLDN10 claudin 10
CNOT4 CCR4-NOT transcription complex, subunit 4
CYTH3 cytohesin 3
DIO2 deiodinase, iodothyronine, type II
DKK3 dickkopf WNT signaling pathway inhibitor 3
EGOT eosinophil granule ontogeny transcript (non-protein coding)
EPHB1 EPH receptor B1
FILIP1L filamin A interacting protein 1-like
FNDC4 fibronectin type III domain containing 4
FUZ fuzzy planar cell polarity protein
GAP43 growth associated protein 43
GHRHR growth hormone releasing hormone receptor
GRIK5 glutamate receptor, ionotropic, kainate 5
HEG1 heart development protein with EGF-like domains 1
HFE hemochromatosis
HIPK3 homeodomain interacting protein kinase 3
HIST1H4D histone cluster 1, H4d
HIST1H4H histone cluster 1, H4h
HPSE2 heparanase 2 (inactive)
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFFO1 intermediate filament family orphan 1
IL12B interleukin 12B
IL18R1 interleukin 18 receptor 1
IL22 interleukin 22
IL5RA interleukin 5 receptor, alpha
IL6ST interleukin 6 signal transducer
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IQCK IQ motif containing K
JAK2 Janus kinase 2
KIAA0319L KIAA0319-like
KIAA0391 KIAA0391
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KITLG KIT ligand
LIMD1 LIM domains containing 1
LIMD2 LIM domain containing 2
LINC00341 long intergenic non-protein coding RNA 341
LOXL3 lysyl oxidase-like 3
LPCAT4 lysophosphatidylcholine acyltransferase 4
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAPK11 mitogen-activated protein kinase 11
MDM4 MDM4, p53 regulator
MFAP3L microfibrillar-associated protein 3-like
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MUC5B mucin 5B, oligomeric mucus/gel-forming
MUC7 mucin 7, secreted
MYOZ1 myozenin 1
NCF4 neutrophil cytosolic factor 4, 40kDa
NCLN nicalin
NDNF neuron-derived neurotrophic factor
NLE1 notchless homolog 1 (Drosophila)
NPY neuropeptide Y
PAPPA2 pappalysin 2
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PHF1 PHD finger protein 1
PHTF2 putative homeodomain transcription factor 2
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RB1 retinoblastoma 1
RBFA ribosome binding factor A (putative)
RFXAP regulatory factor X-associated protein
RTN1 reticulon 1
S1PR1 sphingosine-1-phosphate receptor 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEC14L5 SEC14-like 5 (S. cerevisiae)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SOS2 son of sevenless homolog 2 (Drosophila)
SPACA1 sperm acrosome associated 1
SPATA6 spermatogenesis associated 6
SRSF1 serine/arginine-rich splicing factor 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SYCP2 synaptonemal complex protein 2
TBC1D22A TBC1 domain family, member 22A
TCF3 transcription factor 3
TFCP2L1 transcription factor CP2-like 1
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TUBA3C tubulin, alpha 3c
VIPR2 vasoactive intestinal peptide receptor 2
WNK1 WNK lysine deficient protein kinase 1
WT1-AS WT1 antisense RNA
YTHDC2 YTH domain containing 2
ZBED4 zinc finger, BED-type containing 4

decreased expression

Symbol Name
ACYP2 acylphosphatase 2, muscle type
AGO4 argonaute RISC catalytic component 4
ALOX12 arachidonate 12-lipoxygenase
APOC4 apolipoprotein C-IV
ARC activity-regulated cytoskeleton-associated protein
BST1 bone marrow stromal cell antigen 1
BTBD2 BTB (POZ) domain containing 2
BTF3P11 basic transcription factor 3 pseudogene 11
C17ORF80 chromosome 17 open reading frame 80
C1ORF159 chromosome 1 open reading frame 159
C1RL complement component 1, r subcomponent-like
C5ORF45 chromosome 5 open reading frame 45
C9ORF40 chromosome 9 open reading frame 40
CDON cell adhesion associated, oncogene regulated
CIDEB cell death-inducing DFFA-like effector b
CLDN14 claudin 14
CNGB3 cyclic nucleotide gated channel beta 3
CREB5 cAMP responsive element binding protein 5
CUZD1 CUB and zona pellucida-like domains 1
CYB5R2 cytochrome b5 reductase 2
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DLK2 delta-like 2 homolog (Drosophila)
EFNB1 ephrin-B1
EPN1 epsin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1LB ERO1-like beta (S. cerevisiae)
EXOC6B exocyst complex component 6B
FAM53B family with sequence similarity 53, member B
FANCE Fanconi anemia, complementation group E
FBXL15 F-box and leucine-rich repeat protein 15
FRS3 fibroblast growth factor receptor substrate 3
GRAMD1C GRAM domain containing 1C
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HIST1H2AI histone cluster 1, H2ai
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXB9 homeobox B9
HOXC10 homeobox C10
HSPB6 heat shock protein, alpha-crystallin-related, B6
IRAK4 interleukin-1 receptor-associated kinase 4
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KIAA1107 KIAA1107
KIRREL kin of IRRE like (Drosophila)
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT33A keratin 33A, type I
LOC100286895 cell division cycle 27 homolog pseudogene
LPAR4 lysophosphatidic acid receptor 4
LRRC15 leucine rich repeat containing 15
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MLYCD malonyl-CoA decarboxylase
MN1 meningioma (disrupted in balanced translocation) 1
MNMIP1 manchette microtubule inner protein 1
MTSS1L metastasis suppressor 1-like
MYO1F myosin IF
NARFL nuclear prelamin A recognition factor-like
NID2 nidogen 2 (osteonidogen)
NT5M 5',3'-nucleotidase, mitochondrial
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
ONECUT2 one cut homeobox 2
OSMR oncostatin M receptor
PARP3 poly (ADP-ribose) polymerase family, member 3
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PEX26 peroxisomal biogenesis factor 26
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD3 phospholipase D family, member 3
PLXNB3 plexin B3
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POMT2 protein-O-mannosyltransferase 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRB3 proline-rich protein BstNI subfamily 3
PRPH peripherin
PRR7 proline rich 7 (synaptic)
RGCC regulator of cell cycle
RHOBTB2 Rho-related BTB domain containing 2
RNF126P1 ring finger protein 126 pseudogene 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SARM1 sterile alpha and TIR motif containing 1
SAYSD1 SAYSVFN motif domain containing 1
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SMR3A submaxillary gland androgen regulated protein 3A
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TAGLN3 transgelin 3
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TESPA1 thymocyte expressed, positive selection associated 1
TIGD6 tigger transposable element derived 6
TMEM121 transmembrane protein 121
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TPRA1 transmembrane protein, adipocyte asscociated 1
TRIM25 tripartite motif containing 25
TSNAXIP1 translin-associated factor X interacting protein 1
VGLL3 vestigial-like family member 3
ZC3H12A zinc finger CCCH-type containing 12A
ZNF528 zinc finger protein 528
ZNF862 zinc finger protein 862