oxantel-6738 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the oxantel-6738 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ACPP acid phosphatase, prostate
ADAM11 ADAM metallopeptidase domain 11
ADAM22 ADAM metallopeptidase domain 22
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADRBK2 adrenergic, beta, receptor kinase 2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ARRB1 arrestin, beta 1
ASCL1 achaete-scute family bHLH transcription factor 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BAAT bile acid CoA:amino acid N-acyltransferase
BMP8B bone morphogenetic protein 8b
C1ORF61 chromosome 1 open reading frame 61
C21ORF2 chromosome 21 open reading frame 2
CCDC30 coiled-coil domain containing 30
CCDC7 coiled-coil domain containing 7
CCL2 chemokine (C-C motif) ligand 2
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CLCA2 chloride channel accessory 2
CLCNKB chloride channel, voltage-sensitive Kb
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DGCR8 DGCR8 microprocessor complex subunit
DOCK9 dedicator of cytokinesis 9
DOK4 docking protein 4
DPF1 D4, zinc and double PHD fingers family 1
DPY19L1P1 DPY19L1 pseudogene 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELOVL5 ELOVL fatty acid elongase 5
ESRRG estrogen-related receptor gamma
FLT1 fms-related tyrosine kinase 1
FOXN2 forkhead box N2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GALR3 galanin receptor 3
GK2 glycerol kinase 2
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR161 G protein-coupled receptor 161
GRK5 G protein-coupled receptor kinase 5
GSTTP1 glutathione S-transferase theta pseudogene 1
HES2 hes family bHLH transcription factor 2
HIPK3 homeodomain interacting protein kinase 3
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IL12RB1 interleukin 12 receptor, beta 1
IL32 interleukin 32
ING4 inhibitor of growth family, member 4
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KITLG KIT ligand
LARP7 La ribonucleoprotein domain family, member 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK8 mitogen-activated protein kinase 8
MAU2 MAU2 sister chromatid cohesion factor
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MNMIP1 manchette microtubule inner protein 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
NF1 neurofibromin 1
NFX1 nuclear transcription factor, X-box binding 1
NIPAL2 NIPA-like domain containing 2
OSBPL10 oxysterol binding protein-like 10
OSGIN2 oxidative stress induced growth inhibitor family member 2
OXCT2 3-oxoacid CoA transferase 2
PACRG PARK2 co-regulated
PCDHA9 protocadherin alpha 9
PCDHB3 protocadherin beta 3
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLN phospholamban
PLXNA2 plexin A2
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PRB4 proline-rich protein BstNI subfamily 4
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAB35 RAB35, member RAS oncogene family
RARB retinoic acid receptor, beta
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RB1 retinoblastoma 1
RHO rhodopsin
SCAPER S-phase cyclin A-associated protein in the ER
SGSM3 small G protein signaling modulator 3
SH2D3C SH2 domain containing 3C
SHOX2 short stature homeobox 2
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SOCS3 suppressor of cytokine signaling 3
SRP72 signal recognition particle 72kDa
STATH statherin
TP63 tumor protein p63
TRIL TLR4 interactor with leucine-rich repeats
TRIM3 tripartite motif containing 3
WDR76 WD repeat domain 76
XCR1 chemokine (C motif) receptor 1
YIPF4 Yip1 domain family, member 4
ZC2HC1C zinc finger, C2HC-type containing 1C
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZMAT4 zinc finger, matrin-type 4
ZNF609 zinc finger protein 609
ZNF768 zinc finger protein 768

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ALPK1 alpha-kinase 1
ANXA2P1 annexin A2 pseudogene 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AURKC aurora kinase C
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BIRC3 baculoviral IAP repeat containing 3
BSPRY B-box and SPRY domain containing
C14ORF105 chromosome 14 open reading frame 105
C17ORF70 chromosome 17 open reading frame 70
C1ORF159 chromosome 1 open reading frame 159
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5ORF42 chromosome 5 open reading frame 42
C7ORF43 chromosome 7 open reading frame 43
CAMKMT calmodulin-lysine N-methyltransferase
CAPN15 calpain 15
CARTPT CART prepropeptide
CDK6 cyclin-dependent kinase 6
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CNN1 calponin 1, basic, smooth muscle
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPZ carboxypeptidase Z
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDN dendrin
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DNM3 dynamin 3
DSPP dentin sialophosphoprotein
DTX2 deltex 2, E3 ubiquitin ligase
ELSPBP1 epididymal sperm binding protein 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM13C family with sequence similarity 13, member C
FAM53B family with sequence similarity 53, member B
FBRS fibrosin
FGF23 fibroblast growth factor 23
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLT4 fms-related tyrosine kinase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GATA4 GATA binding protein 4
GIF gastric intrinsic factor (vitamin B synthesis)
GRM4 glutamate receptor, metabotropic 4
HIST1H2BO histone cluster 1, H2bo
HIST1H3C histone cluster 1, H3c
HOXC4 homeobox C4
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
ICOS inducible T-cell co-stimulator
IL24 interleukin 24
IL36RN interleukin 36 receptor antagonist
IL6 interleukin 6
KDM8 lysine (K)-specific demethylase 8
KIRREL kin of IRRE like (Drosophila)
KLHL28 kelch-like family member 28
LAMB2 laminin, beta 2 (laminin S)
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LINC00115 long intergenic non-protein coding RNA 115
LMO7 LIM domain 7
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MAP3K7CL MAP3K7 C-terminal like
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MYH15 myosin, heavy chain 15
NKX3-2 NK3 homeobox 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PAQR6 progestin and adipoQ receptor family member VI
PARD6A par-6 family cell polarity regulator alpha
PKD2L2 polycystic kidney disease 2-like 2
PLD3 phospholipase D family, member 3
POLL polymerase (DNA directed), lambda
PRAMEF10 PRAME family member 10
RHOBTB2 Rho-related BTB domain containing 2
RIN1 Ras and Rab interactor 1
RUNX1-IT1 RUNX1 intronic transcript 1
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SNHG3 small nucleolar RNA host gene 3
SPATA1 spermatogenesis associated 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SYNPO synaptopodin
TAOK1 TAO kinase 1
TMEM120B transmembrane protein 120B
TOR4A torsin family 4, member A
TRAPPC13 trafficking protein particle complex 13
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WDR62 WD repeat domain 62
WNT1 wingless-type MMTV integration site family, member 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF253 zinc finger protein 253
ZNF358 zinc finger protein 358
ZNF442 zinc finger protein 442
ZNF816 zinc finger protein 816
ZNF862 zinc finger protein 862
ZXDB zinc finger, X-linked, duplicated B