oxaprozin-4530 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the oxaprozin-4530 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADARB1 adenosine deaminase, RNA-specific, B1
ADGRL3 adhesion G protein-coupled receptor L3
APOBR apolipoprotein B receptor
AQP9 aquaporin 9
BCAS1 breast carcinoma amplified sequence 1
BTG2 BTG family, member 2
C11ORF1 chromosome 11 open reading frame 1
C14ORF105 chromosome 14 open reading frame 105
C17ORF53 chromosome 17 open reading frame 53
C4BPA complement component 4 binding protein, alpha
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCL16 chemokine (C-C motif) ligand 16
CD244 CD244 molecule, natural killer cell receptor 2B4
CDC14B cell division cycle 14B
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CISH cytokine inducible SH2-containing protein
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CPA2 carboxypeptidase A2 (pancreatic)
CTNS cystinosin, lysosomal cystine transporter
CUL7 cullin 7
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAPK2 death-associated protein kinase 2
DCX doublecortin
ENOX2 ecto-NOX disulfide-thiol exchanger 2
FBXO31 F-box protein 31
FGF5 fibroblast growth factor 5
FLJ22184
FRMD1 FERM domain containing 1
FRS2 fibroblast growth factor receptor substrate 2
GATA4 GATA binding protein 4
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GK glycerol kinase
GMPR guanosine monophosphate reductase
GPR176 G protein-coupled receptor 176
GREB1L growth regulation by estrogen in breast cancer-like
HDAC11 histone deacetylase 11
HIST1H2AL histone cluster 1, H2al
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ING4 inhibitor of growth family, member 4
INO80D INO80 complex subunit D
IQCK IQ motif containing K
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
LMAN1 lectin, mannose-binding, 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAP3K7CL MAP3K7 C-terminal like
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MECOM MDS1 and EVI1 complex locus
METTL7A methyltransferase like 7A
MGC2889 uncharacterized protein MGC2889
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MTMR3 myotubularin related protein 3
MTMR8 myotubularin related protein 8
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEFM neurofilament, medium polypeptide
NGF nerve growth factor (beta polypeptide)
NPPB natriuretic peptide B
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRP1 neuropilin 1
NT5M 5',3'-nucleotidase, mitochondrial
PARP6 poly (ADP-ribose) polymerase family, member 6
PDIA2 protein disulfide isomerase family A, member 2
PHEX phosphate regulating endopeptidase homolog, X-linked
PHOX2A paired-like homeobox 2a
PLD1 phospholipase D1, phosphatidylcholine-specific
PPP4R4 protein phosphatase 4, regulatory subunit 4
RBMS2 RNA binding motif, single stranded interacting protein 2
RFPL3S RFPL3 antisense
RGS7 regulator of G-protein signaling 7
RHCE Rh blood group, CcEe antigens
RNF6 ring finger protein (C3H2C3 type) 6
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RPS3A ribosomal protein S3A
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SAFB scaffold attachment factor B
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC26A1 solute carrier family 26 (anion exchanger), member 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOX15 SRY (sex determining region Y)-box 15
STEAP4 STEAP family member 4
SYT11 synaptotagmin XI
TBC1D22B TBC1 domain family, member 22B
TLDC1 TBC/LysM-associated domain containing 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TRIM2 tripartite motif containing 2
TYRO3 TYRO3 protein tyrosine kinase
WSB1 WD repeat and SOCS box containing 1
ZEB1 zinc finger E-box binding homeobox 1
ZNF268 zinc finger protein 268
ZNF334 zinc finger protein 334
ZNF589 zinc finger protein 589
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
AGMAT agmatine ureohydrolase (agmatinase)
ANXA2P1 annexin A2 pseudogene 1
ARMCX4 armadillo repeat containing, X-linked 4
ASPHD1 aspartate beta-hydroxylase domain containing 1
AXIN1 axin 1
BAK1 BCL2-antagonist/killer 1
BIRC3 baculoviral IAP repeat containing 3
BTF3P12 basic transcription factor 3 pseudogene 12
C1QTNF1 C1q and tumor necrosis factor related protein 1
C22ORF29 chromosome 22 open reading frame 29
C3 complement component 3
C3ORF18 chromosome 3 open reading frame 18
C5ORF45 chromosome 5 open reading frame 45
CA5B carbonic anhydrase VB, mitochondrial
CA9 carbonic anhydrase IX
CAMKMT calmodulin-lysine N-methyltransferase
CCDC9 coiled-coil domain containing 9
CDADC1 cytidine and dCMP deaminase domain containing 1
CDH10 cadherin 10, type 2 (T2-cadherin)
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNTLN centlein, centrosomal protein
CORO1A coronin, actin binding protein, 1A
CORT cortistatin
CPED1 cadherin-like and PC-esterase domain containing 1
CREB5 cAMP responsive element binding protein 5
CXCL3 chemokine (C-X-C motif) ligand 3
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNAL4 dynein, axonemal, light chain 4
DNM3 dynamin 3
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELP3 elongator acetyltransferase complex subunit 3
FBXL7 F-box and leucine-rich repeat protein 7
FMO4 flavin containing monooxygenase 4
FUZ fuzzy planar cell polarity protein
H2AFJ H2A histone family, member J
HIST1H1E histone cluster 1, H1e
HIST1H2AM histone cluster 1, H2am
HOXA7 homeobox A7
IL4R interleukin 4 receptor
ITPKA inositol-trisphosphate 3-kinase A
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIAA0319L KIAA0319-like
KRT86 keratin 86, type II
LAX1 lymphocyte transmembrane adaptor 1
LIN7B lin-7 homolog B (C. elegans)
LOC100127972 uncharacterized LOC100127972
LOC390998 ribosomal protein L10 pseudogene
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC61 leucine rich repeat containing 61
MN1 meningioma (disrupted in balanced translocation) 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MST1 macrophage stimulating 1
MX1 MX dynamin-like GTPase 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDE1 nudE neurodevelopment protein 1
NDP Norrie disease (pseudoglioma)
NDRG4 NDRG family member 4
NPFFR1 neuropeptide FF receptor 1
NT5DC3 5'-nucleotidase domain containing 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PALM paralemmin
PCBP4 poly(rC) binding protein 4
PDE12 phosphodiesterase 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PHC1 polyhomeotic homolog 1 (Drosophila)
PID1 phosphotyrosine interaction domain containing 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLAC8 placenta-specific 8
PORCN porcupine homolog (Drosophila)
PPT2 palmitoyl-protein thioesterase 2
PRB3 proline-rich protein BstNI subfamily 3
RAB3A RAB3A, member RAS oncogene family
RIN1 Ras and Rab interactor 1
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SAMD9 sterile alpha motif domain containing 9
SEC14L2 SEC14-like 2 (S. cerevisiae)
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLMO1 slowmo homolog 1 (Drosophila)
SPATA2L spermatogenesis associated 2-like
SPRYD7 SPRY domain containing 7
TBXAS1 thromboxane A synthase 1 (platelet)
TCTN2 tectonic family member 2
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM159 transmembrane protein 159
TMEM19 transmembrane protein 19
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TPCN1 two pore segment channel 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TUBA3C tubulin, alpha 3c
USP19 ubiquitin specific peptidase 19
YOD1 YOD1 deubiquitinase
ZBTB39 zinc finger and BTB domain containing 39
ZNF552 zinc finger protein 552