oxedrine-3578 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the oxedrine-3578 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ACTA1 actin, alpha 1, skeletal muscle
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALS2CL ALS2 C-terminal like
ANGPT4 angiopoietin 4
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARC activity-regulated cytoskeleton-associated protein
ATF3 activating transcription factor 3
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C2 complement component 2
CA5B carbonic anhydrase VB, mitochondrial
CACTIN cactin, spliceosome C complex subunit
CAMK1 calcium/calmodulin-dependent protein kinase I
CD300A CD300a molecule
CNTN1 contactin 1
COL11A1 collagen, type XI, alpha 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DDIT3 DNA-damage-inducible transcript 3
DFNB31 deafness, autosomal recessive 31
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DMTN dematin actin binding protein
DYM dymeclin
EGR1 early growth response 1
EHD2 EH-domain containing 2
ELOVL2 ELOVL fatty acid elongase 2
FAM46C family with sequence similarity 46, member C
FBXO21 F-box protein 21
FGF16 fibroblast growth factor 16
FOS FBJ murine osteosarcoma viral oncogene homolog
FUT2 fucosyltransferase 2 (secretor status included)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GIF gastric intrinsic factor (vitamin B synthesis)
GJB3 gap junction protein, beta 3, 31kDa
HBB hemoglobin, beta
HES2 hes family bHLH transcription factor 2
HEXIM1 hexamethylene bis-acetamide inducible 1
HIST1H2BO histone cluster 1, H2bo
HMGN5 high mobility group nucleosome binding domain 5
ICOSLG inducible T-cell co-stimulator ligand
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
INHBE inhibin, beta E
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB4 integrin, beta 4
ITGB8 integrin, beta 8
JUN jun proto-oncogene
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNK10 potassium channel, two pore domain subfamily K, member 10
LEPR leptin receptor
LINC00341 long intergenic non-protein coding RNA 341
LY9 lymphocyte antigen 9
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK14 mitogen-activated protein kinase 14
MVD mevalonate (diphospho) decarboxylase
NAT6 N-acetyltransferase 6 (GCN5-related)
NF1 neurofibromin 1
NKX3-2 NK3 homeobox 2
NT5M 5',3'-nucleotidase, mitochondrial
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OCA2 oculocutaneous albinism II
OVOL1 ovo-like zinc finger 1
PDE4D phosphodiesterase 4D, cAMP-specific
PDLIM7 PDZ and LIM domain 7 (enigma)
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLCB2 phospholipase C, beta 2
PLD3 phospholipase D family, member 3
PLIN2 perilipin 2
PLK3 polo-like kinase 3
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PTPRO protein tyrosine phosphatase, receptor type, O
PXDC1 PX domain containing 1
RFTN1 raftlin, lipid raft linker 1
RGS12 regulator of G-protein signaling 12
RNF144A ring finger protein 144A
RNF19B ring finger protein 19B
RPL23AP32 ribosomal protein L23a pseudogene 32
SLC35E2 solute carrier family 35, member E2
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SORCS3 sortilin-related VPS10 domain containing receptor 3
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STK24 serine/threonine kinase 24
SUGP1 SURP and G patch domain containing 1
TAS2R1 taste receptor, type 2, member 1
TCF3 transcription factor 3
TCP10L t-complex 10-like
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACTL8 actin-like 8
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALPK1 alpha-kinase 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARPIN actin-related protein 2/3 complex inhibitor
ARRB1 arrestin, beta 1
BIRC7 baculoviral IAP repeat containing 7
BRAF B-Raf proto-oncogene, serine/threonine kinase
C14ORF79 chromosome 14 open reading frame 79
C1ORF159 chromosome 1 open reading frame 159
C1QTNF3 C1q and tumor necrosis factor related protein 3
C2ORF27A chromosome 2 open reading frame 27A
CAPG capping protein (actin filament), gelsolin-like
CCDC121 coiled-coil domain containing 121
CD82 CD82 molecule
CHML choroideremia-like (Rab escort protein 2)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CRY2 cryptochrome circadian clock 2
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FADS2 fatty acid desaturase 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLRA1 glycine receptor, alpha 1
GPR176 G protein-coupled receptor 176
GUSBP3 glucuronidase, beta pseudogene 3
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1E histone cluster 1, H1e
HIST1H2AL histone cluster 1, H2al
HOXC10 homeobox C10
INCENP inner centromere protein antigens 135/155kDa
INPP1 inositol polyphosphate-1-phosphatase
KIF13A kinesin family member 13A
KRT13 keratin 13, type I
LAMB1 laminin, beta 1
LIN7A lin-7 homolog A (C. elegans)
LINC00597 long intergenic non-protein coding RNA 597
MAGEA6 melanoma antigen family A6
MAN2C1 mannosidase, alpha, class 2C, member 1
MFAP2 microfibrillar-associated protein 2
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MRPS18C mitochondrial ribosomal protein S18C
MTSS1L metastasis suppressor 1-like
MXD3 MAX dimerization protein 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NBEAL2 neurobeachin-like 2
NLGN1 neuroligin 1
NPFFR1 neuropeptide FF receptor 1
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PADI1 peptidyl arginine deiminase, type I
PCDHB3 protocadherin beta 3
PDE8B phosphodiesterase 8B
PGP phosphoglycolate phosphatase
PKN1 protein kinase N1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PMP22 peripheral myelin protein 22
POM121 POM121 transmembrane nucleoporin
POPDC3 popeye domain containing 3
PRSS22 protease, serine, 22
QPCTL glutaminyl-peptide cyclotransferase-like
RAD54L2 RAD54-like 2 (S. cerevisiae)
REM1 RAS (RAD and GEM)-like GTP-binding 1
RIN2 Ras and Rab interactor 2
RNF126P1 ring finger protein 126 pseudogene 1
S100A4 S100 calcium binding protein A4
SCD5 stearoyl-CoA desaturase 5
SECTM1 secreted and transmembrane 1
SERGEF secretion regulating guanine nucleotide exchange factor
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SRD5A3 steroid 5 alpha-reductase 3
STAG3 stromal antigen 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TESC tescalcin
TLN1 talin 1
TPK1 thiamin pyrophosphokinase 1
USP19 ubiquitin specific peptidase 19
VEZT vezatin, adherens junctions transmembrane protein
WDR25 WD repeat domain 25
WDR4 WD repeat domain 4
WDR76 WD repeat domain 76
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB22 zinc finger and BTB domain containing 22
ZNF286A zinc finger protein 286A
ZNF423 zinc finger protein 423
ZNF652 zinc finger protein 652
ZNF747 zinc finger protein 747