| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the oxedrine-6156 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADCY2 | adenylate cyclase 2 (brain) |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AK1 | adenylate kinase 1 |
| AREG | amphiregulin |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP9B | ATPase, class II, type 9B |
| AXL | AXL receptor tyrosine kinase |
| BAIAP2 | BAI1-associated protein 2 |
| BIN1 | bridging integrator 1 |
| BTBD18 | BTB (POZ) domain containing 18 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CCDC132 | coiled-coil domain containing 132 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CDCP1 | CUB domain containing protein 1 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLTA | clathrin, light chain A |
| COL11A2 | collagen, type XI, alpha 2 |
| COPE | coatomer protein complex, subunit epsilon |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CREM | cAMP responsive element modulator |
| CSN2 | casein beta |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| EFNA5 | ephrin-A5 |
| ERICH1 | glutamate-rich 1 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 |
| FBXO2 | F-box protein 2 |
| FDXR | ferredoxin reductase |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GAS7 | growth arrest-specific 7 |
| GLI3 | GLI family zinc finger 3 |
| GPC1 | glypican 1 |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HTRA1 | HtrA serine peptidase 1 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFI44 | interferon-induced protein 44 |
| IFI44L | interferon-induced protein 44-like |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IL21R | interleukin 21 receptor |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 |
| KIR3DS1 | killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 |
| KYNU | kynureninase |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMNA | lamin A/C |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAP7 | microtubule-associated protein 7 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MOB3B | MOB kinase activator 3B |
| MX1 | MX dynamin-like GTPase 1 |
| NDNF | neuron-derived neurotrophic factor |
| NEBL | nebulette |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PICK1 | protein interacting with PRKCA 1 |
| PIR | pirin (iron-binding nuclear protein) |
| PLXNC1 | plexin C1 |
| PTCRA | pre T-cell antigen receptor alpha |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| REC8 | REC8 meiotic recombination protein |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SPRR1B | small proline-rich protein 1B |
| SRCAP | Snf2-related CREBBP activator protein |
| SV2B | synaptic vesicle glycoprotein 2B |
| SYN3 | synapsin III |
| TCP10 | t-complex 10 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| THBS1 | thrombospondin 1 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMEM2 | transmembrane protein 2 |
| TTC38 | tetratricopeptide repeat domain 38 |
| ZMYND11 | zinc finger, MYND-type containing 11 |
| ZNF688 | zinc finger protein 688 |
| ZNF93 | zinc finger protein 93 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADRB2 | adrenoceptor beta 2, surface |
| ALPK1 | alpha-kinase 1 |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| ARRB1 | arrestin, beta 1 |
| ATG10 | autophagy related 10 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CBR3 | carbonyl reductase 3 |
| CD1C | CD1c molecule |
| CDHR2 | cadherin-related family member 2 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CLEC4E | C-type lectin domain family 4, member E |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM102A | family with sequence similarity 102, member A |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GP6 | glycoprotein VI (platelet) |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA1107 | KIAA1107 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| LYRM9 | LYR motif containing 9 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAK | male germ cell-associated kinase |
| MEFV | Mediterranean fever |
| MVD | mevalonate (diphospho) decarboxylase |
| MYL5 | myosin, light chain 5, regulatory |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NDE1 | nudE neurodevelopment protein 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OMG | oligodendrocyte myelin glycoprotein |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PDGFD | platelet derived growth factor D |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| POLL | polymerase (DNA directed), lambda |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PRKCZ | protein kinase C, zeta |
| PRMT7 | protein arginine methyltransferase 7 |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| PYGB | phosphorylase, glycogen; brain |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RWDD2A | RWD domain containing 2A |
| SH2D4A | SH2 domain containing 4A |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SNX29P2 | sorting nexin 29 pseudogene 2 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STX1A | syntaxin 1A (brain) |
| TEC | tec protein tyrosine kinase |
| TEP1 | telomerase-associated protein 1 |
| TEX15 | testis expressed 15 |
| TMEM212 | transmembrane protein 212 |
| TRIM9 | tripartite motif containing 9 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSPAN13 | tetraspanin 13 |
| UBQLN4 | ubiquilin 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| UPB1 | ureidopropionase, beta |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VN1R1 | vomeronasal 1 receptor 1 |
| WDR4 | WD repeat domain 4 |
| XYLT2 | xylosyltransferase II |
| YY2 | YY2 transcription factor |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF155 | zinc finger protein 155 |
| ZNF276 | zinc finger protein 276 |
| ZNF345 | zinc finger protein 345 |
| ZNF428 | zinc finger protein 428 |
| ZNF862 | zinc finger protein 862 |