oxedrine-6156 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the oxedrine-6156 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ACTA2 actin, alpha 2, smooth muscle, aorta
ADCY2 adenylate cyclase 2 (brain)
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AK1 adenylate kinase 1
AREG amphiregulin
ARL2BP ADP-ribosylation factor-like 2 binding protein
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP9B ATPase, class II, type 9B
AXL AXL receptor tyrosine kinase
BAIAP2 BAI1-associated protein 2
BIN1 bridging integrator 1
BTBD18 BTB (POZ) domain containing 18
C19ORF73 chromosome 19 open reading frame 73
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CCDC132 coiled-coil domain containing 132
CD40 CD40 molecule, TNF receptor superfamily member 5
CDCP1 CUB domain containing protein 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLTA clathrin, light chain A
COL11A2 collagen, type XI, alpha 2
COPE coatomer protein complex, subunit epsilon
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CREM cAMP responsive element modulator
CSN2 casein beta
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
DCAF4 DDB1 and CUL4 associated factor 4
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EFNA5 ephrin-A5
ERICH1 glutamate-rich 1
F2RL3 coagulation factor II (thrombin) receptor-like 3
FBXO2 F-box protein 2
FDXR ferredoxin reductase
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAS7 growth arrest-specific 7
GLI3 GLI family zinc finger 3
GPC1 glypican 1
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HTRA1 HtrA serine peptidase 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IL21R interleukin 21 receptor
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IQSEC1 IQ motif and Sec7 domain 1
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
KCNK1 potassium channel, two pore domain subfamily K, member 1
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KYNU kynureninase
LINC00597 long intergenic non-protein coding RNA 597
LMNA lamin A/C
LPAR1 lysophosphatidic acid receptor 1
LY6D lymphocyte antigen 6 complex, locus D
MAP7 microtubule-associated protein 7
MARCKS myristoylated alanine-rich protein kinase C substrate
MCM3AP minichromosome maintenance complex component 3 associated protein
MFSD6 major facilitator superfamily domain containing 6
MOB3B MOB kinase activator 3B
MX1 MX dynamin-like GTPase 1
NDNF neuron-derived neurotrophic factor
NEBL nebulette
NQO1 NAD(P)H dehydrogenase, quinone 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PICK1 protein interacting with PRKCA 1
PIR pirin (iron-binding nuclear protein)
PLXNC1 plexin C1
PTCRA pre T-cell antigen receptor alpha
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
REC8 REC8 meiotic recombination protein
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SPRR1B small proline-rich protein 1B
SRCAP Snf2-related CREBBP activator protein
SV2B synaptic vesicle glycoprotein 2B
SYN3 synapsin III
TCP10 t-complex 10
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
THBS1 thrombospondin 1
TM4SF5 transmembrane 4 L six family member 5
TMEM2 transmembrane protein 2
TTC38 tetratricopeptide repeat domain 38
ZMYND11 zinc finger, MYND-type containing 11
ZNF688 zinc finger protein 688
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADRB2 adrenoceptor beta 2, surface
ALPK1 alpha-kinase 1
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARRB1 arrestin, beta 1
ATG10 autophagy related 10
BAHD1 bromo adjacent homology domain containing 1
BIRC3 baculoviral IAP repeat containing 3
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C11ORF63 chromosome 11 open reading frame 63
C16ORF59 chromosome 16 open reading frame 59
C9ORF9 chromosome 9 open reading frame 9
CBR3 carbonyl reductase 3
CD1C CD1c molecule
CDHR2 cadherin-related family member 2
CDR2L cerebellar degeneration-related protein 2-like
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLEC4E C-type lectin domain family 4, member E
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CYSLTR1 cysteinyl leukotriene receptor 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ELSPBP1 epididymal sperm binding protein 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM102A family with sequence similarity 102, member A
FGFBP1 fibroblast growth factor binding protein 1
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GP6 glycoprotein VI (platelet)
GTF2IRD1 GTF2I repeat domain containing 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HYAL2 hyaluronoglucosaminidase 2
IGFBP4 insulin-like growth factor binding protein 4
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KAT2A K(lysine) acetyltransferase 2A
KDM8 lysine (K)-specific demethylase 8
KIAA1107 KIAA1107
KLF3 Kruppel-like factor 3 (basic)
LNPEP leucyl/cystinyl aminopeptidase
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRK1 leucine-rich repeat kinase 1
LYPLA2P1 lysophospholipase II pseudogene 1
LYRM9 LYR motif containing 9
LZTR1 leucine-zipper-like transcription regulator 1
MAK male germ cell-associated kinase
MEFV Mediterranean fever
MVD mevalonate (diphospho) decarboxylase
MYL5 myosin, light chain 5, regulatory
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NDE1 nudE neurodevelopment protein 1
NPFFR1 neuropeptide FF receptor 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NT5DC3 5'-nucleotidase domain containing 3
OMG oligodendrocyte myelin glycoprotein
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PDGFD platelet derived growth factor D
PHC1 polyhomeotic homolog 1 (Drosophila)
POLL polymerase (DNA directed), lambda
POM121L2 POM121 transmembrane nucleoporin-like 2
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRKCZ protein kinase C, zeta
PRMT7 protein arginine methyltransferase 7
PWAR5 Prader Willi/Angelman region RNA 5
PYGB phosphorylase, glycogen; brain
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RWDD2A RWD domain containing 2A
SH2D4A SH2 domain containing 4A
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SNX29P2 sorting nexin 29 pseudogene 2
STEAP1 six transmembrane epithelial antigen of the prostate 1
STX1A syntaxin 1A (brain)
TEC tec protein tyrosine kinase
TEP1 telomerase-associated protein 1
TEX15 testis expressed 15
TMEM212 transmembrane protein 212
TRIM9 tripartite motif containing 9
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN13 tetraspanin 13
UBQLN4 ubiquilin 4
UNC119 unc-119 homolog (C. elegans)
UPB1 ureidopropionase, beta
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VN1R1 vomeronasal 1 receptor 1
WDR4 WD repeat domain 4
XYLT2 xylosyltransferase II
YY2 YY2 transcription factor
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF155 zinc finger protein 155
ZNF276 zinc finger protein 276
ZNF345 zinc finger protein 345
ZNF428 zinc finger protein 428
ZNF862 zinc finger protein 862