oxedrine-6798 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the oxedrine-6798 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APOM apolipoprotein M
ARHGAP44 Rho GTPase activating protein 44
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BTF3P11 basic transcription factor 3 pseudogene 11
C1ORF105 chromosome 1 open reading frame 105
CARTPT CART prepropeptide
CAV2 caveolin 2
CCDC28B coiled-coil domain containing 28B
CCNK cyclin K
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK6 cyclin-dependent kinase 6
CDSN corneodesmosin
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHKB choline kinase beta
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLCN7 chloride channel, voltage-sensitive 7
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COL11A2 collagen, type XI, alpha 2
CSHL1 chorionic somatomammotropin hormone-like 1
CSTA cystatin A (stefin A)
CXORF21 chromosome X open reading frame 21
DACH1 dachshund family transcription factor 1
DAPK2 death-associated protein kinase 2
DKFZP434L187 uncharacterized LOC26082
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK4 docking protein 4
DPY19L1P1 DPY19L1 pseudogene 1
DRD2 dopamine receptor D2
EFS embryonal Fyn-associated substrate
EHBP1L1 EH domain binding protein 1-like 1
ERCC2 excision repair cross-complementation group 2
ETNK2 ethanolamine kinase 2
FBLN1 fibulin 1
FLJ22184
FRMD4B FERM domain containing 4B
FYB FYN binding protein
GK3P glycerol kinase 3 pseudogene
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GRM1 glutamate receptor, metabotropic 1
GSAP gamma-secretase activating protein
GSPT1 G1 to S phase transition 1
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFNA14 interferon, alpha 14
IGHM immunoglobulin heavy constant mu
IL12RB1 interleukin 12 receptor, beta 1
IL22 interleukin 22
KLHL25 kelch-like family member 25
KRT15 keratin 15, type I
LOXL2 lysyl oxidase-like 2
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MEF2C myocyte enhancer factor 2C
MINK1 misshapen-like kinase 1
MMP13 matrix metallopeptidase 13
MTMR7 myotubularin related protein 7
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
OSBPL10 oxysterol binding protein-like 10
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PBX2 pre-B-cell leukemia homeobox 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLXND1 plexin D1
POLM polymerase (DNA directed), mu
PPP6R2 protein phosphatase 6, regulatory subunit 2
PRDM16 PR domain containing 16
PRKCA protein kinase C, alpha
PRODH proline dehydrogenase (oxidase) 1
PRX periaxin
PTCRA pre T-cell antigen receptor alpha
PVT1 Pvt1 oncogene (non-protein coding)
RAB3B RAB3B, member RAS oncogene family
RAD51 RAD51 recombinase
RASA3 RAS p21 protein activator 3
RNF126P1 ring finger protein 126 pseudogene 1
RPH3A rabphilin 3A
RRBP1 ribosome binding protein 1
RUSC2 RUN and SH3 domain containing 2
SAYSD1 SAYSVFN motif domain containing 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC43A3 solute carrier family 43, member 3
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SYT12 synaptotagmin XII
TAPBP TAP binding protein (tapasin)
TBL1Y transducin (beta)-like 1, Y-linked
TGM2 transglutaminase 2
TINAGL1 tubulointerstitial nephritis antigen-like 1
TLE2 transducin-like enhancer of split 2
TPMT thiopurine S-methyltransferase
TRAK1 trafficking protein, kinesin binding 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VASH2 vasohibin 2
VPS9D1 VPS9 domain containing 1
ZNF37BP zinc finger protein 37B, pseudogene

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADGRG2 adhesion G protein-coupled receptor G2
ALPK1 alpha-kinase 1
ANKRD40 ankyrin repeat domain 40
ANXA2P3 annexin A2 pseudogene 3
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
BAX BCL2-associated X protein
BRAF B-Raf proto-oncogene, serine/threonine kinase
C11ORF30 chromosome 11 open reading frame 30
C19ORF73 chromosome 19 open reading frame 73
C22ORF46 chromosome 22 open reading frame 46
C7ORF43 chromosome 7 open reading frame 43
CCP110 centriolar coiled coil protein 110kDa
CD79B CD79b molecule, immunoglobulin-associated beta
CENPJ centromere protein J
CORT cortistatin
CSAD cysteine sulfinic acid decarboxylase
DAZAP1 DAZ associated protein 1
DCAF13 DDB1 and CUL4 associated factor 13
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DSCAM Down syndrome cell adhesion molecule
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FAM131A family with sequence similarity 131, member A
FBXO22 F-box protein 22
FLCN folliculin
GATA6 GATA binding protein 6
GDAP1 ganglioside induced differentiation associated protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GRTP1 growth hormone regulated TBC protein 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H3G histone cluster 1, H3g
HMOX1 heme oxygenase 1
ICK intestinal cell (MAK-like) kinase
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IMPAD1 inositol monophosphatase domain containing 1
JMJD4 jumonji domain containing 4
KCNK15 potassium channel, two pore domain subfamily K, member 15
KIAA0895 KIAA0895
KIFC1 kinesin family member C1
LINC00115 long intergenic non-protein coding RNA 115
LMNB1 lamin B1
LPCAT3 lysophosphatidylcholine acyltransferase 3
MAN2C1 mannosidase, alpha, class 2C, member 1
MGC12488
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MITF microphthalmia-associated transcription factor
MNS1 meiosis-specific nuclear structural 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLXNA3 plexin A3
POMT2 protein-O-mannosyltransferase 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRR14L proline rich 14-like
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTPRE protein tyrosine phosphatase, receptor type, E
R3HCC1L R3H domain and coiled-coil containing 1-like
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RASAL1 RAS protein activator like 1 (GAP1 like)
RGS2 regulator of G-protein signaling 2
RIN2 Ras and Rab interactor 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF121 ring finger protein 121
RNF170 ring finger protein 170
SLC12A9 solute carrier family 12, member 9
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SP1 Sp1 transcription factor
STK16 serine/threonine kinase 16
TEP1 telomerase-associated protein 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THBS3 thrombospondin 3
THRAP3 thyroid hormone receptor associated protein 3
TMEM183A transmembrane protein 183A
TMOD3 tropomodulin 3 (ubiquitous)
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAPPC11 trafficking protein particle complex 11
TRIM45 tripartite motif containing 45
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP27X ubiquitin specific peptidase 27, X-linked
WDR76 WD repeat domain 76
ZBTB22 zinc finger and BTB domain containing 22
ZNF250 zinc finger protein 250
ZNF280D zinc finger protein 280D
ZNF302 zinc finger protein 302
ZNF428 zinc finger protein 428
ZNF480 zinc finger protein 480
ZNF573 zinc finger protein 573
ZNF768 zinc finger protein 768