oxetacaine-1484 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the oxetacaine-1484 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
APOL2 apolipoprotein L, 2
ASPH aspartate beta-hydroxylase
BAAT bile acid CoA:amino acid N-acyltransferase
BAIAP3 BAI1-associated protein 3
BFSP2 beaded filament structural protein 2, phakinin
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCDC28B coiled-coil domain containing 28B
CCDC68 coiled-coil domain containing 68
CD83 CD83 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CEMIP cell migration inducing protein, hyaluronan binding
CEP112 centrosomal protein 112kDa
CERS4 ceramide synthase 4
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIB2 calcium and integrin binding family member 2
CLCF1 cardiotrophin-like cytokine factor 1
CNR2 cannabinoid receptor 2 (macrophage)
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DNAL4 dynein, axonemal, light chain 4
ELN elastin
F3 coagulation factor III (thromboplastin, tissue factor)
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
HDAC5 histone deacetylase 5
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXD1 homeobox D1
ICAM1 intercellular adhesion molecule 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KAZN kazrin, periplakin interacting protein
KRIT1 KRIT1, ankyrin repeat containing
LOXL2 lysyl oxidase-like 2
LRRC23 leucine rich repeat containing 23
LSP1 lymphocyte-specific protein 1
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAP1A microtubule-associated protein 1A
MARK4 MAP/microtubule affinity-regulating kinase 4
MBNL2 muscleblind-like splicing regulator 2
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MID1 midline 1
MOCS1 molybdenum cofactor synthesis 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MUC3B mucin 3B, cell surface associated
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NIPAL2 NIPA-like domain containing 2
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NR6A1 nuclear receptor subfamily 6, group A, member 1
NTF3 neurotrophin 3
OSGIN2 oxidative stress induced growth inhibitor family member 2
PAPPA2 pappalysin 2
PDLIM4 PDZ and LIM domain 4
PI15 peptidase inhibitor 15
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PODNL1 podocan-like 1
POU5F1B POU class 5 homeobox 1B
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRPF18 pre-mRNA processing factor 18
RAB6A RAB6A, member RAS oncogene family
RIMS3 regulating synaptic membrane exocytosis 3
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPAIN RPA interacting protein
RPL13P5 ribosomal protein L13 pseudogene 5
RPS14 ribosomal protein S14
RTEL1 regulator of telomere elongation helicase 1
RYR2 ryanodine receptor 2 (cardiac)
SCAND2P SCAN domain containing 2 pseudogene
SCAPER S-phase cyclin A-associated protein in the ER
SCD5 stearoyl-CoA desaturase 5
SCHIP1 schwannomin interacting protein 1
SETD4 SET domain containing 4
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC12A8 solute carrier family 12, member 8
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMAD3 SMAD family member 3
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SOX15 SRY (sex determining region Y)-box 15
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SYMPK symplekin
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TRIM68 tripartite motif containing 68
UBQLN4 ubiquilin 4
UNC93B1 unc-93 homolog B1 (C. elegans)
UPK3B uroplakin 3B
USP27X ubiquitin specific peptidase 27, X-linked
VCAN versican
VWA5A von Willebrand factor A domain containing 5A
WIZ widely interspaced zinc finger motifs
WNT16 wingless-type MMTV integration site family, member 16
WSCD1 WSC domain containing 1
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBTB33 zinc finger and BTB domain containing 33
ZC2HC1C zinc finger, C2HC-type containing 1C
ZCCHC4 zinc finger, CCHC domain containing 4
ZFPL1 zinc finger protein-like 1
ZNF324 zinc finger protein 324
ZNF37BP zinc finger protein 37B, pseudogene

decreased expression

Symbol Name
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACAD10 acyl-CoA dehydrogenase family, member 10
AFF4 AF4/FMR2 family, member 4
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ATP7B ATPase, Cu++ transporting, beta polypeptide
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCORL1 BCL6 corepressor-like 1
BMP4 bone morphogenetic protein 4
C5ORF45 chromosome 5 open reading frame 45
CAMTA2 calmodulin binding transcription activator 2
CARD8 caspase recruitment domain family, member 8
CBX4 chromobox homolog 4
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP290 centrosomal protein 290kDa
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLDN15 claudin 15
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CST6 cystatin E/M
EPHA2 EPH receptor A2
EPN3 epsin 3
ERN1 endoplasmic reticulum to nucleus signaling 1
FAM114A2 family with sequence similarity 114, member A2
FBXO22 F-box protein 22
FGD1 FYVE, RhoGEF and PH domain containing 1
FJX1 four jointed box 1 (Drosophila)
GLCE glucuronic acid epimerase
GMEB1 glucocorticoid modulatory element binding protein 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HOXC13 homeobox C13
HP1BP3 heterochromatin protein 1, binding protein 3
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
ITPKB inositol-trisphosphate 3-kinase B
KIAA0141 KIAA0141
KIAA0556 KIAA0556
KIAA0895 KIAA0895
KPTN kaptin (actin binding protein)
KRI1 KRI1 homolog (S. cerevisiae)
LOC100287590 uncharacterized LOC100287590
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LYPD3 LY6/PLAUR domain containing 3
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCMBP minichromosome maintenance complex binding protein
MED22 mediator complex subunit 22
MYO9A myosin IXA
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NDRG4 NDRG family member 4
NR2C2 nuclear receptor subfamily 2, group C, member 2
NRGN neurogranin (protein kinase C substrate, RC3)
PACS1 phosphofurin acidic cluster sorting protein 1
PAQR6 progestin and adipoQ receptor family member VI
PDGFRL platelet-derived growth factor receptor-like
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PLA2G10 phospholipase A2, group X
PLAC8 placenta-specific 8
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLD3 phospholipase D family, member 3
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKCSH protein kinase C substrate 80K-H
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RANGRF RAN guanine nucleotide release factor
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RWDD3 RWD domain containing 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SF3A3 splicing factor 3a, subunit 3, 60kDa
SGK1 serum/glucocorticoid regulated kinase 1
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SNUPN snurportin 1
SOWAHC sosondowah ankyrin repeat domain family member C
SOX12 SRY (sex determining region Y)-box 12
SOX3 SRY (sex determining region Y)-box 3
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TDRD1 tudor domain containing 1
TEAD3 TEA domain family member 3
TMEM53 transmembrane protein 53
TMEM57 transmembrane protein 57
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAPPC11 trafficking protein particle complex 11
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
WDR62 WD repeat domain 62
WFDC2 WAP four-disulfide core domain 2
WLS wntless Wnt ligand secretion mediator
ZBED1 zinc finger, BED-type containing 1
ZBTB48 zinc finger and BTB domain containing 48
ZC3H3 zinc finger CCCH-type containing 3
ZNF211 zinc finger protein 211