oxetacaine-1903 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the oxetacaine-1903 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ARSJ arylsulfatase family, member J
ATP13A1 ATPase type 13A1
AXIN1 axin 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C1QL1 complement component 1, q subcomponent-like 1
C2CD2L C2CD2-like
C7ORF26 chromosome 7 open reading frame 26
CD53 CD53 molecule
CDC27 cell division cycle 27
CDK12 cyclin-dependent kinase 12
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLDN3 claudin 3
COL4A5 collagen, type IV, alpha 5
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUS2 dihydrouridine synthase 2
DUSP6 dual specificity phosphatase 6
F3 coagulation factor III (thromboplastin, tissue factor)
FAF1 Fas (TNFRSF6) associated factor 1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GANAB glucosidase, alpha; neutral AB
GATAD2A GATA zinc finger domain containing 2A
GFER growth factor, augmenter of liver regeneration
GMIP GEM interacting protein
GRK5 G protein-coupled receptor kinase 5
HACD1 3-hydroxyacyl-CoA dehydratase 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGKV1D-13 immunoglobulin kappa variable 1D-13
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
INSIG1 insulin induced gene 1
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCTD13 potassium channel tetramerization domain containing 13
KDM4B lysine (K)-specific demethylase 4B
KDM5A lysine (K)-specific demethylase 5A
KLF12 Kruppel-like factor 12
KLHL21 kelch-like family member 21
KPTN kaptin (actin binding protein)
LDLR low density lipoprotein receptor
LOC647070 uncharacterized LOC647070
MAGEA3 melanoma antigen family A3
MAN1B1 mannosidase, alpha, class 1B, member 1
MICALL1 MICAL-like 1
MOAP1 modulator of apoptosis 1
MSMO1 methylsterol monooxygenase 1
MTF1 metal-regulatory transcription factor 1
MTMR2 myotubularin related protein 2
MTMR4 myotubularin related protein 4
NACA nascent polypeptide-associated complex alpha subunit
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PGS1 phosphatidylglycerophosphate synthase 1
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLXNB2 plexin B2
PPAP2A phosphatidic acid phosphatase type 2A
PRRC2A proline-rich coiled-coil 2A
PRY PTPN13-like, Y-linked
RAB40B RAB40B, member RAS oncogene family
RNF123 ring finger protein 123
RNFT2 ring finger protein, transmembrane 2
RPL7 ribosomal protein L7
RPS11 ribosomal protein S11
RSBN1 round spermatid basic protein 1
RUSC2 RUN and SH3 domain containing 2
SBNO1 strawberry notch homolog 1 (Drosophila)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCPEP1 serine carboxypeptidase 1
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SETD2 SET domain containing 2
SGSM3 small G protein signaling modulator 3
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC12A8 solute carrier family 12, member 8
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC25A44 solute carrier family 25, member 44
SP3 Sp3 transcription factor
SQLE squalene epoxidase
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SREBF2 sterol regulatory element binding transcription factor 2
STX1A syntaxin 1A (brain)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TOR4A torsin family 4, member A
TP53TG1 TP53 target 1 (non-protein coding)
TRIM68 tripartite motif containing 68
TSC2 tuberous sclerosis 2
USF2 upstream transcription factor 2, c-fos interacting
YTHDC2 YTH domain containing 2
ZNF292 zinc finger protein 292
ZNF318 zinc finger protein 318
ZNF395 zinc finger protein 395
ZNF408 zinc finger protein 408
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ABLIM3 actin binding LIM protein family, member 3
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ANXA3 annexin A3
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARL5A ADP-ribosylation factor-like 5A
ATG14 autophagy related 14
AUNIP aurora kinase A and ninein interacting protein
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL10 B-cell CLL/lymphoma 10
BEX1 brain expressed, X-linked 1
BMI1 BMI1 proto-oncogene, polycomb ring finger
C3ORF14 chromosome 3 open reading frame 14
CASP8AP2 caspase 8 associated protein 2
CCNB2 cyclin B2
CDH3 cadherin 3, type 1, P-cadherin (placental)
CEP85 centrosomal protein 85kDa
CFL1 cofilin 1 (non-muscle)
CINP cyclin-dependent kinase 2 interacting protein
CNN3 calponin 3, acidic
CPOX coproporphyrinogen oxidase
CROT carnitine O-octanoyltransferase
CRYZ crystallin, zeta (quinone reductase)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUEDC2 CUE domain containing 2
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DCK deoxycytidine kinase
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1
DFNA5 deafness, autosomal dominant 5
DOCK1 dedicator of cytokinesis 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
FAM46A family with sequence similarity 46, member A
FBXW12 F-box and WD repeat domain containing 12
FRG1 FSHD region gene 1
GGCT gamma-glutamylcyclotransferase
GLTP glycolipid transfer protein
HIST1H4C histone cluster 1, H4c
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IRS1 insulin receptor substrate 1
JADE3 jade family PHD finger 3
KIF11 kinesin family member 11
LACTB2 lactamase, beta 2
LGMN legumain
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LZTR1 leucine-zipper-like transcription regulator 1
MACROD1 MACRO domain containing 1
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL12B myosin, light chain 12B, regulatory
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
NEK4 NIMA-related kinase 4
NHEJ1 nonhomologous end-joining factor 1
NMI N-myc (and STAT) interactor
NUCLEOLIN nucleolin multifunctional protein
PARG poly (ADP-ribose) glycohydrolase
PARPBP PARP1 binding protein
PLCD1 phospholipase C, delta 1
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRCP prolylcarboxypeptidase (angiotensinase C)
PRSS2 protease, serine, 2 (trypsin 2)
QDPR quinoid dihydropteridine reductase
RAB5B RAB5B, member RAS oncogene family
RAB9A RAB9A, member RAS oncogene family
RANBP6 RAN binding protein 6
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RFWD3 ring finger and WD repeat domain 3
RIT1 Ras-like without CAAX 1
RPL34 ribosomal protein L34
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RPS17P5 ribosomal protein S17 pseudogene 5
SECTM1 secreted and transmembrane 1
SLC35E3 solute carrier family 35, member E3
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SNRPF small nuclear ribonucleoprotein polypeptide F
SOAT1 sterol O-acyltransferase 1
SPAG16 sperm associated antigen 16
STAU2 staufen double-stranded RNA binding protein 2
STXBP1 syntaxin binding protein 1
STXBP3 syntaxin binding protein 3
TBCCD1 TBCC domain containing 1
TFB2M transcription factor B2, mitochondrial
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THOC7 THO complex 7
TM9SF2 transmembrane 9 superfamily member 2
TRIM16 tripartite motif containing 16
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSPAN13 tetraspanin 13
TSPYL4 TSPY-like 4
TTI1 TELO2 interacting protein 1
UBA5 ubiquitin-like modifier activating enzyme 5
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)
ZCCHC8 zinc finger, CCHC domain containing 8
ZDHHC7 zinc finger, DHHC-type containing 7
ZNF217 zinc finger protein 217
ZNF587 zinc finger protein 587