| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the oxetacaine-1984 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACA | acetyl-CoA carboxylase alpha |
| ACTN2 | actinin, alpha 2 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| ADNP2 | ADNP homeobox 2 |
| AGTPBP1 | ATP/GTP binding protein 1 |
| ALOX15B | arachidonate 15-lipoxygenase, type B |
| ARMCX3 | armadillo repeat containing, X-linked 3 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BAX | BCL2-associated X protein |
| BCL3 | B-cell CLL/lymphoma 3 |
| BNIP1 | BCL2/adenovirus E1B 19kDa interacting protein 1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C22ORF24 | chromosome 22 open reading frame 24 |
| C5AR1 | complement component 5a receptor 1 |
| CA7 | carbonic anhydrase VII |
| CCNJ | cyclin J |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COG5 | component of oligomeric golgi complex 5 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DPY19L1 | dpy-19-like 1 (C. elegans) |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EFCAB2 | EF-hand calcium binding domain 2 |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| ENOSF1 | enolase superfamily member 1 |
| FAM172A | family with sequence similarity 172, member A |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| FTO | fat mass and obesity associated |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GDF11 | growth differentiation factor 11 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GSAP | gamma-secretase activating protein |
| GYPB | glycophorin B (MNS blood group) |
| HIRA | histone cell cycle regulator |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KIAA0586 | KIAA0586 |
| KIAA1109 | KIAA1109 |
| KLK1 | kallikrein 1 |
| LETM1 | leucine zipper-EF-hand containing transmembrane protein 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYT1 | myelin transcription factor 1 |
| N4BP1 | NEDD4 binding protein 1 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NINJ2 | ninjurin 2 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| OSBPL3 | oxysterol binding protein-like 3 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PGRMC2 | progesterone receptor membrane component 2 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLD2 | phospholipase D2 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| RREB1 | ras responsive element binding protein 1 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SFN | stratifin |
| SH3BP2 | SH3-domain binding protein 2 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPON2 | spondin 2, extracellular matrix protein |
| SQLE | squalene epoxidase |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein |
| STXBP1 | syntaxin binding protein 1 |
| SUSD6 | sushi domain containing 6 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM134 | transmembrane protein 134 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TRIB2 | tribbles pseudokinase 2 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| UNC45A | unc-45 homolog A (C. elegans) |
| WBP2 | WW domain binding protein 2 |
| XYLT2 | xylosyltransferase II |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| Symbol | Name |
|---|---|
| AATF | apoptosis antagonizing transcription factor |
| ABHD3 | abhydrolase domain containing 3 |
| ABHD4 | abhydrolase domain containing 4 |
| APH1B | APH1B gamma secretase subunit |
| ATAD2 | ATPase family, AAA domain containing 2 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| BCCIP | BRCA2 and CDKN1A interacting protein |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CASZ1 | castor zinc finger 1 |
| CD244 | CD244 molecule, natural killer cell receptor 2B4 |
| CDK9 | cyclin-dependent kinase 9 |
| CENPC | centromere protein C |
| CENPQ | centromere protein Q |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CNPY3 | canopy FGF signaling regulator 3 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COMMD10 | COMM domain containing 10 |
| COQ4 | coenzyme Q4 |
| COQ6 | coenzyme Q6 monooxygenase |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) |
| DENND4A | DENN/MADD domain containing 4A |
| DEPDC1 | DEP domain containing 1 |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| ECI1 | enoyl-CoA delta isomerase 1 |
| ECM1 | extracellular matrix protein 1 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ERCC2 | excision repair cross-complementation group 2 |
| EXOSC9 | exosome component 9 |
| FAM193B | family with sequence similarity 193, member B |
| FASTKD5 | FAST kinase domains 5 |
| FBXO5 | F-box protein 5 |
| G6PD | glucose-6-phosphate dehydrogenase |
| GMCL1 | germ cell-less, spermatogenesis associated 1 |
| GPS1 | G protein pathway suppressor 1 |
| GTF3C4 | general transcription factor IIIC, polypeptide 4, 90kDa |
| HIST1H1E | histone cluster 1, H1e |
| IL4R | interleukin 4 receptor |
| JMJD1C | jumonji domain containing 1C |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LYRM2 | LYR motif containing 2 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MEST | mesoderm specific transcript |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MOSPD3 | motile sperm domain containing 3 |
| MRPS15 | mitochondrial ribosomal protein S15 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| NEMF | nuclear export mediator factor |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| NVL | nuclear VCP-like |
| OCEL1 | occludin/ELL domain containing 1 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PDCD5 | programmed cell death 5 |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase |
| PLK1 | polo-like kinase 1 |
| PNKP | polynucleotide kinase 3'-phosphatase |
| PODNL1 | podocan-like 1 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PPIEL | peptidylprolyl isomerase E-like pseudogene |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RAD54L | RAD54-like (S. cerevisiae) |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SETD6 | SET domain containing 6 |
| SIRT6 | sirtuin 6 |
| SIRT7 | sirtuin 7 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SMYD5 | SMYD family member 5 |
| SNRPC | small nuclear ribonucleoprotein polypeptide C |
| SPI1 | Spi-1 proto-oncogene |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| STRA13 | stimulated by retinoic acid 13 |
| TEFM | transcription elongation factor, mitochondrial |
| TMEM11 | transmembrane protein 11 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRAIP | TRAF interacting protein |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
| UBE2M | ubiquitin-conjugating enzyme E2M |
| UBXN2B | UBX domain protein 2B |
| USP20 | ubiquitin specific peptidase 20 |
| USP6 | ubiquitin specific peptidase 6 |
| VILL | villin-like |
| XPA | xeroderma pigmentosum, complementation group A |
| ZNF281 | zinc finger protein 281 |
| ZNF8 | zinc finger protein 8 |
| ZW10 | zw10 kinetochore protein |
