Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the oxolinic acid-2103 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
ABCD4 | ATP-binding cassette, sub-family D (ALD), member 4 |
ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
ACTN4 | actinin, alpha 4 |
ADAP2 | ArfGAP with dual PH domains 2 |
ANKMY1 | ankyrin repeat and MYND domain containing 1 |
ANKRD12 | ankyrin repeat domain 12 |
AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
ARID1A | AT rich interactive domain 1A (SWI-like) |
ASTN2 | astrotactin 2 |
ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
ATXN3 | ataxin 3 |
BAX | BCL2-associated X protein |
BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
C11ORF63 | chromosome 11 open reading frame 63 |
CALD1 | caldesmon 1 |
CASP2 | caspase 2, apoptosis-related cysteine peptidase |
CLEC4A | C-type lectin domain family 4, member A |
CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
DAPK3 | death-associated protein kinase 3 |
DSC1 | desmocollin 1 |
FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
FNDC4 | fibronectin type III domain containing 4 |
FOXA2 | forkhead box A2 |
GAREM | GRB2 associated, regulator of MAPK1 |
GLE1 | GLE1 RNA export mediator |
GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
HOXA11 | homeobox A11 |
HOXC10 | homeobox C10 |
HPS1 | Hermansky-Pudlak syndrome 1 |
HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 |
INO80B | INO80 complex subunit B |
INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
IQCE | IQ motif containing E |
ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
JUND | jun D proto-oncogene |
KDM5A | lysine (K)-specific demethylase 5A |
KIAA1462 | KIAA1462 |
KLF3 | Kruppel-like factor 3 (basic) |
LARGE | like-glycosyltransferase |
LDB1 | LIM domain binding 1 |
LEF1 | lymphoid enhancer-binding factor 1 |
LRP3 | low density lipoprotein receptor-related protein 3 |
LTC4S | leukotriene C4 synthase |
LYPD3 | LY6/PLAUR domain containing 3 |
MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
MBD2 | methyl-CpG binding domain protein 2 |
MCC | mutated in colorectal cancers |
METTL5 | methyltransferase like 5 |
MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
MUC3B | mucin 3B, cell surface associated |
MYO7A | myosin VIIA |
NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
NIPAL2 | NIPA-like domain containing 2 |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
PALMD | palmdelphin |
PARVA | parvin, alpha |
PCNX | pecanex homolog (Drosophila) |
PDAP1 | PDGFA associated protein 1 |
PF4 | platelet factor 4 |
PLXNC1 | plexin C1 |
PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
RAB31 | RAB31, member RAS oncogene family |
RARS | arginyl-tRNA synthetase |
RBM3 | RNA binding motif (RNP1, RRM) protein 3 |
REST | RE1-silencing transcription factor |
RGS10 | regulator of G-protein signaling 10 |
RNF2 | ring finger protein 2 |
RPL10 | ribosomal protein L10 |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
SENP6 | SUMO1/sentrin specific peptidase 6 |
SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
SLITRK5 | SLIT and NTRK-like family, member 5 |
SOBP | sine oculis binding protein homolog (Drosophila) |
TAT | tyrosine aminotransferase |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
THRAP3 | thyroid hormone receptor associated protein 3 |
TLE4 | transducin-like enhancer of split 4 |
VASP | vasodilator-stimulated phosphoprotein |
XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
YIPF4 | Yip1 domain family, member 4 |
ZBTB22 | zinc finger and BTB domain containing 22 |
ZC2HC1C | zinc finger, C2HC-type containing 1C |
ZFR | zinc finger RNA binding protein |
ZFX | zinc finger protein, X-linked |
ZHX3 | zinc fingers and homeoboxes 3 |
ZMIZ2 | zinc finger, MIZ-type containing 2 |
Symbol | Name |
---|---|
ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
ABHD17B | abhydrolase domain containing 17B |
ACTG2 | actin, gamma 2, smooth muscle, enteric |
AEN | apoptosis enhancing nuclease |
ALS2CL | ALS2 C-terminal like |
ANXA2P3 | annexin A2 pseudogene 3 |
APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
ARL14 | ADP-ribosylation factor-like 14 |
ATF7IP2 | activating transcription factor 7 interacting protein 2 |
ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
C19ORF54 | chromosome 19 open reading frame 54 |
C9ORF3 | chromosome 9 open reading frame 3 |
CA5BP1 | carbonic anhydrase VB pseudogene 1 |
CABIN1 | calcineurin binding protein 1 |
CAMTA2 | calmodulin binding transcription activator 2 |
CHKB | choline kinase beta |
CLASRP | CLK4-associating serine/arginine rich protein |
CLCN5 | chloride channel, voltage-sensitive 5 |
CLEC2B | C-type lectin domain family 2, member B |
CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
DEAF1 | DEAF1 transcription factor |
EFNA3 | ephrin-A3 |
EPHB6 | EPH receptor B6 |
ESM1 | endothelial cell-specific molecule 1 |
FAM184A | family with sequence similarity 184, member A |
FAM53B | family with sequence similarity 53, member B |
FBXL7 | F-box and leucine-rich repeat protein 7 |
GJC1 | gap junction protein, gamma 1, 45kDa |
GOLGA8B | golgin A8 family, member B |
GSDMD | gasdermin D |
GSR | glutathione reductase |
HMHA1 | histocompatibility (minor) HA-1 |
HYI | hydroxypyruvate isomerase (putative) |
IL17RA | interleukin 17 receptor A |
IREB2 | iron-responsive element binding protein 2 |
IRF2 | interferon regulatory factor 2 |
KIAA0556 | KIAA0556 |
KIAA0894 | KIAA0894 protein |
KIAA1549L | KIAA1549-like |
LMBR1L | limb development membrane protein 1-like |
LRRC61 | leucine rich repeat containing 61 |
MAGEA6 | melanoma antigen family A6 |
MFSD10 | major facilitator superfamily domain containing 10 |
MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
ODF2 | outer dense fiber of sperm tails 2 |
OLFML3 | olfactomedin-like 3 |
OVGP1 | oviductal glycoprotein 1, 120kDa |
P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
PARD6A | par-6 family cell polarity regulator alpha |
PARM1 | prostate androgen-regulated mucin-like protein 1 |
PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
PDLIM2 | PDZ and LIM domain 2 (mystique) |
PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
PLXNA3 | plexin A3 |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
PRAME | preferentially expressed antigen in melanoma |
PRR15L | proline rich 15-like |
PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
RAB33B | RAB33B, member RAS oncogene family |
RANBP17 | RAN binding protein 17 |
RFX7 | regulatory factor X, 7 |
RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
RIN1 | Ras and Rab interactor 1 |
SAMD9 | sterile alpha motif domain containing 9 |
SETD6 | SET domain containing 6 |
SHPK | sedoheptulokinase |
SHROOM2 | shroom family member 2 |
SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
SLC46A3 | solute carrier family 46, member 3 |
SPEG | SPEG complex locus |
ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
STAG3 | stromal antigen 3 |
STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
STBD1 | starch binding domain 1 |
STK16 | serine/threonine kinase 16 |
TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
TBC1D19 | TBC1 domain family, member 19 |
TEX40 | testis expressed 40 |
TH | tyrosine hydroxylase |
THBS3 | thrombospondin 3 |
TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
TMEM183A | transmembrane protein 183A |
TRIM45 | tripartite motif containing 45 |
TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
TTC26 | tetratricopeptide repeat domain 26 |
USP36 | ubiquitin specific peptidase 36 |
ZBED8 | zinc finger, BED-type containing 8 |
ZBTB25 | zinc finger and BTB domain containing 25 |
ZDHHC14 | zinc finger, DHHC-type containing 14 |
ZNF16 | zinc finger protein 16 |
ZNF189 | zinc finger protein 189 |
ZNF324 | zinc finger protein 324 |
ZNF862 | zinc finger protein 862 |