Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the oxolinic acid-2266 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACBD4 | acyl-CoA binding domain containing 4 |
AGER | advanced glycosylation end product-specific receptor |
ARHGAP28 | Rho GTPase activating protein 28 |
ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
ASMT | acetylserotonin O-methyltransferase |
ATF7 | activating transcription factor 7 |
ATN1 | atrophin 1 |
B3GAT1 | beta-1,3-glucuronyltransferase 1 |
BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
BMP10 | bone morphogenetic protein 10 |
CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
CALCR | calcitonin receptor |
CCL19 | chemokine (C-C motif) ligand 19 |
CCNK | cyclin K |
CD101 | CD101 molecule |
CD300A | CD300a molecule |
CD58 | CD58 molecule |
CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
CNTLN | centlein, centrosomal protein |
CPQ | carboxypeptidase Q |
CRMP1 | collapsin response mediator protein 1 |
CSF1 | colony stimulating factor 1 (macrophage) |
CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
CTSZ | cathepsin Z |
CYLD | cylindromatosis (turban tumor syndrome) |
DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
DLC1 | DLC1 Rho GTPase activating protein |
DMBT1 | deleted in malignant brain tumors 1 |
DNAI2 | dynein, axonemal, intermediate chain 2 |
DTX3 | deltex 3, E3 ubiquitin ligase |
EIF3F | eukaryotic translation initiation factor 3, subunit F |
ETV5 | ets variant 5 |
ETV7 | ets variant 7 |
EXOSC1 | exosome component 1 |
FAM46C | family with sequence similarity 46, member C |
FBXO40 | F-box protein 40 |
FCGR1B | Fc fragment of IgG, high affinity Ib, receptor (CD64) |
FGFR1 | fibroblast growth factor receptor 1 |
GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
GAS7 | growth arrest-specific 7 |
GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
GRM8 | glutamate receptor, metabotropic 8 |
GSK3A | glycogen synthase kinase 3 alpha |
HCG4 | HLA complex group 4 (non-protein coding) |
HFE | hemochromatosis |
HIST1H2BM | histone cluster 1, H2bm |
HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
HMGN5 | high mobility group nucleosome binding domain 5 |
HOXB3 | homeobox B3 |
HOXC5 | homeobox C5 |
HSD3B1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
INO80D | INO80 complex subunit D |
IRAK3 | interleukin-1 receptor-associated kinase 3 |
KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
KIF5A | kinesin family member 5A |
KSR1 | kinase suppressor of ras 1 |
LAPTM5 | lysosomal protein transmembrane 5 |
LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
LRRC6 | leucine rich repeat containing 6 |
LRRC75B | leucine rich repeat containing 75B |
MAB21L1 | mab-21-like 1 (C. elegans) |
MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
MEF2D | myocyte enhancer factor 2D |
MEG3 | maternally expressed 3 (non-protein coding) |
MINK1 | misshapen-like kinase 1 |
MLANA | melan-A |
MTSS1L | metastasis suppressor 1-like |
NRP1 | neuropilin 1 |
PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
PAX2 | paired box 2 |
PAX9 | paired box 9 |
PBX2 | pre-B-cell leukemia homeobox 2 |
PCBP3 | poly(rC) binding protein 3 |
PCDHB17P | protocadherin beta 17 pseudogene |
PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
PDLIM4 | PDZ and LIM domain 4 |
PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
PRKCI | protein kinase C, iota |
PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
RGS12 | regulator of G-protein signaling 12 |
RIN3 | Ras and Rab interactor 3 |
RS1 | retinoschisin 1 |
SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
STAT2 | signal transducer and activator of transcription 2, 113kDa |
STEAP4 | STEAP family member 4 |
TCF25 | transcription factor 25 (basic helix-loop-helix) |
TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
TEX15 | testis expressed 15 |
TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
TPMT | thiopurine S-methyltransferase |
VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) |
ZNF175 | zinc finger protein 175 |
Symbol | Name |
---|---|
A1CF | APOBEC1 complementation factor |
ABHD17B | abhydrolase domain containing 17B |
ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
ACTN4 | actinin, alpha 4 |
ADAP2 | ArfGAP with dual PH domains 2 |
ALG12 | ALG12, alpha-1,6-mannosyltransferase |
ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
ALPK1 | alpha-kinase 1 |
ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
ANXA1 | annexin A1 |
ARRB2 | arrestin, beta 2 |
BCORL1 | BCL6 corepressor-like 1 |
C22ORF29 | chromosome 22 open reading frame 29 |
C22ORF46 | chromosome 22 open reading frame 46 |
C2ORF27A | chromosome 2 open reading frame 27A |
C5AR2 | complement component 5a receptor 2 |
C6ORF47 | chromosome 6 open reading frame 47 |
CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
CD82 | CD82 molecule |
CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta |
CLCF1 | cardiotrophin-like cytokine factor 1 |
CLSTN2 | calsyntenin 2 |
CNR2 | cannabinoid receptor 2 (macrophage) |
CRELD1 | cysteine-rich with EGF-like domains 1 |
DGAT1 | diacylglycerol O-acyltransferase 1 |
DIXDC1 | DIX domain containing 1 |
DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
F2R | coagulation factor II (thrombin) receptor |
FAM188A | family with sequence similarity 188, member A |
FGD1 | FYVE, RhoGEF and PH domain containing 1 |
FOXN2 | forkhead box N2 |
GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
GLRA1 | glycine receptor, alpha 1 |
GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
GPATCH2L | G patch domain containing 2-like |
GPR143 | G protein-coupled receptor 143 |
GRB7 | growth factor receptor-bound protein 7 |
GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
GUSBP3 | glucuronidase, beta pseudogene 3 |
HIRA | histone cell cycle regulator |
HIST1H2AI | histone cluster 1, H2ai |
HIST2H2AA3 | histone cluster 2, H2aa3 |
IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
IMPACT | impact RWD domain protein |
INCENP | inner centromere protein antigens 135/155kDa |
IPO8 | importin 8 |
KCTD7 | potassium channel tetramerization domain containing 7 |
KLHL21 | kelch-like family member 21 |
LIF | leukemia inhibitory factor |
LMNB1 | lamin B1 |
LYPD3 | LY6/PLAUR domain containing 3 |
MBTD1 | mbt domain containing 1 |
METTL8 | methyltransferase like 8 |
MSI1 | musashi RNA-binding protein 1 |
MVD | mevalonate (diphospho) decarboxylase |
NBEAL2 | neurobeachin-like 2 |
NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
NKX3-2 | NK3 homeobox 2 |
NPTX1 | neuronal pentraxin I |
NXPH4 | neurexophilin 4 |
OTUD3 | OTU deubiquitinase 3 |
PCSK7 | proprotein convertase subtilisin/kexin type 7 |
PEX26 | peroxisomal biogenesis factor 26 |
PHEX | phosphate regulating endopeptidase homolog, X-linked |
PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
PITX2 | paired-like homeodomain 2 |
PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
PRODH | proline dehydrogenase (oxidase) 1 |
PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
RARS | arginyl-tRNA synthetase |
RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
RPL10L | ribosomal protein L10-like |
SCRN3 | secernin 3 |
SEC61G | Sec61 gamma subunit |
SFXN1 | sideroflexin 1 |
SKI | SKI proto-oncogene |
SNTA1 | syntrophin, alpha 1 |
STARD3 | StAR-related lipid transfer (START) domain containing 3 |
STIM1 | stromal interaction molecule 1 |
SUGP1 | SURP and G patch domain containing 1 |
TBC1D2 | TBC1 domain family, member 2 |
TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
TRIM21 | tripartite motif containing 21 |
TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
UBOX5 | U-box domain containing 5 |
UBQLN4 | ubiquilin 4 |
WDR62 | WD repeat domain 62 |
ZBED1 | zinc finger, BED-type containing 1 |
ZNF227 | zinc finger protein 227 |
ZNF329 | zinc finger protein 329 |
ZNF573 | zinc finger protein 573 |
ZNF611 | zinc finger protein 611 |