oxprenolol-3568 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the oxprenolol-3568 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ADRA1B adrenoceptor alpha 1B
AKAP8L A kinase (PRKA) anchor protein 8-like
ANG angiogenin, ribonuclease, RNase A family, 5
APOE apolipoprotein E
ATN1 atrophin 1
B9D2 B9 protein domain 2
BARX2 BARX homeobox 2
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C10ORF95 chromosome 10 open reading frame 95
C1ORF61 chromosome 1 open reading frame 61
C9ORF9 chromosome 9 open reading frame 9
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMK4 calcium/calmodulin-dependent protein kinase IV
CATSPERB catsper channel auxiliary subunit beta
CCDC181 coiled-coil domain containing 181
CCDC57 coiled-coil domain containing 57
CD1A CD1a molecule
CFHR4 complement factor H-related 4
CFP complement factor properdin
COL3A1 collagen, type III, alpha 1
COLEC11 collectin sub-family member 11
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
DEPDC5 DEP domain containing 5
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPY19L1P1 DPY19L1 pseudogene 1
DUSP9 dual specificity phosphatase 9
EFNA3 ephrin-A3
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC2 excision repair cross-complementation group 2
EXPH5 exophilin 5
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM120C family with sequence similarity 120C
FAXDC2 fatty acid hydroxylase domain containing 2
GLRA2 glycine receptor, alpha 2
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
IQCK IQ motif containing K
IRF4 interferon regulatory factor 4
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KRT19P2 keratin 19 pseudogene 2
KRT31 keratin 31, type I
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMB4 laminin, beta 4
LMO3 LIM domain only 3 (rhombotin-like 2)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAOB monoamine oxidase B
MBD2 methyl-CpG binding domain protein 2
MPO myeloperoxidase
MRC2 mannose receptor, C type 2
MTL5 metallothionein-like 5, testis-specific (tesmin)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVB12B multivesicular body subunit 12B
MXRA5 matrix-remodelling associated 5
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NR2E3 nuclear receptor subfamily 2, group E, member 3
NREP neuronal regeneration related protein
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUP214 nucleoporin 214kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PARP11 poly (ADP-ribose) polymerase family, member 11
PCDH12 protocadherin 12
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLAC4 placenta-specific 4
PLAT plasminogen activator, tissue
PLCD1 phospholipase C, delta 1
PLK4 polo-like kinase 4
POFUT1 protein O-fucosyltransferase 1
PROL1 proline rich, lacrimal 1
PTGDR2 prostaglandin D2 receptor 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PYY2 peptide YY, 2 (pseudogene)
RAB6B RAB6B, member RAS oncogene family
RANBP3 RAN binding protein 3
RBM5 RNA binding motif protein 5
RHBG Rh family, B glycoprotein (gene/pseudogene)
RHEB Ras homolog enriched in brain
RND1 Rho family GTPase 1
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SNCAIP synuclein, alpha interacting protein
SPRR1B small proline-rich protein 1B
SPTBN2 spectrin, beta, non-erythrocytic 2
TGFB2 transforming growth factor, beta 2
TRO trophinin
U2AF2 U2 small nuclear RNA auxiliary factor 2
USH1C Usher syndrome 1C (autosomal recessive, severe)
USP22 ubiquitin specific peptidase 22
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
ZNF236 zinc finger protein 236
ZNF510 zinc finger protein 510
ZSCAN18 zinc finger and SCAN domain containing 18
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
AFF4 AF4/FMR2 family, member 4
AHDC1 AT hook, DNA binding motif, containing 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATP13A2 ATPase type 13A2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAHCC1 BAH domain and coiled-coil containing 1
BRPF1 bromodomain and PHD finger containing, 1
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF68 chromosome 11 open reading frame 68
C7ORF43 chromosome 7 open reading frame 43
CAPG capping protein (actin filament), gelsolin-like
CCDC68 coiled-coil domain containing 68
CCNO cyclin O
CCP110 centriolar coiled coil protein 110kDa
CGA glycoprotein hormones, alpha polypeptide
COCH cochlin
CUEDC1 CUE domain containing 1
EGR3 early growth response 3
FANCC Fanconi anemia, complementation group C
FBXL7 F-box and leucine-rich repeat protein 7
FLJ11710 uncharacterized protein FLJ11710
FRK fyn-related Src family tyrosine kinase
GADD45G growth arrest and DNA-damage-inducible, gamma
GEMIN8 gem (nuclear organelle) associated protein 8
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPATCH3 G patch domain containing 3
GPX2 glutathione peroxidase 2
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOOK1 hook microtubule-tethering protein 1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
ICK intestinal cell (MAK-like) kinase
IGSF1 immunoglobulin superfamily, member 1
IPO8 importin 8
IRF7 interferon regulatory factor 7
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KLF11 Kruppel-like factor 11
LAMB3 laminin, beta 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LNPEP leucyl/cystinyl aminopeptidase
LYPLA2P1 lysophospholipase II pseudogene 1
LZTR1 leucine-zipper-like transcription regulator 1
MAGEA6 melanoma antigen family A6
MAP1S microtubule-associated protein 1S
MFSD11 major facilitator superfamily domain containing 11
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPS18C mitochondrial ribosomal protein S18C
NBEAL2 neurobeachin-like 2
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NR1H2 nuclear receptor subfamily 1, group H, member 2
NUPL2 nucleoporin like 2
PADI1 peptidyl arginine deiminase, type I
PELI1 pellino E3 ubiquitin protein ligase 1
PPT2 palmitoyl-protein thioesterase 2
RAB33B RAB33B, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM4B RNA binding motif protein 4B
ROM1 retinal outer segment membrane protein 1
RPL10L ribosomal protein L10-like
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SHARPIN SHANK-associated RH domain interactor
SIX1 SIX homeobox 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLMO1 slowmo homolog 1 (Drosophila)
SOX3 SRY (sex determining region Y)-box 3
SP1 Sp1 transcription factor
SPAG4 sperm associated antigen 4
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYCP2 synaptonemal complex protein 2
TEAD3 TEA domain family member 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM120B transmembrane protein 120B
TMEM121 transmembrane protein 121
TOM1 target of myb1 (chicken)
TPK1 thiamin pyrophosphokinase 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP19 ubiquitin specific peptidase 19
USP20 ubiquitin specific peptidase 20
WDR18 WD repeat domain 18
WDR4 WD repeat domain 4
WLS wntless Wnt ligand secretion mediator
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBED1 zinc finger, BED-type containing 1
ZNF16 zinc finger protein 16
ZNF219 zinc finger protein 219
ZNF492 zinc finger protein 492
ZNF652 zinc finger protein 652
ZNF668 zinc finger protein 668