oxprenolol-7225 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the oxprenolol-7225 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACVR1B activin A receptor, type IB
AK2 adenylate kinase 2
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOC1 apolipoprotein C-I
ARMC8 armadillo repeat containing 8
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCL9 B-cell CLL/lymphoma 9
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CA11 carbonic anhydrase XI
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CASP8 caspase 8, apoptosis-related cysteine peptidase
CD53 CD53 molecule
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLCA1 chloride channel accessory 1
CLCN7 chloride channel, voltage-sensitive 7
CLEC10A C-type lectin domain family 10, member A
CPD carboxypeptidase D
CREBZF CREB/ATF bZIP transcription factor
CSF1 colony stimulating factor 1 (macrophage)
CYTH1 cytohesin 1
DLK2 delta-like 2 homolog (Drosophila)
DOK4 docking protein 4
EFNB3 ephrin-B3
ERAP1 endoplasmic reticulum aminopeptidase 1
FAM134B family with sequence similarity 134, member B
FBXL2 F-box and leucine-rich repeat protein 2
FBXO22 F-box protein 22
FILIP1L filamin A interacting protein 1-like
GBP1 guanylate binding protein 1, interferon-inducible
GFI1 growth factor independent 1 transcription repressor
GOLGA8A golgin A8 family, member A
GPR182 G protein-coupled receptor 182
GRK4 G protein-coupled receptor kinase 4
GSN gelsolin
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
GYPB glycophorin B (MNS blood group)
HCRTR2 hypocretin (orexin) receptor 2
HDLBP high density lipoprotein binding protein
HFE hemochromatosis
HIPK3 homeodomain interacting protein kinase 3
HOXC8 homeobox C8
ICOSLG inducible T-cell co-stimulator ligand
LECT1 leukocyte cell derived chemotaxin 1
LEPR leptin receptor
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LZTR1 leucine-zipper-like transcription regulator 1
MARK2 MAP/microtubule affinity-regulating kinase 2
NDRG2 NDRG family member 2
NPY5R neuropeptide Y receptor Y5
NRG2 neuregulin 2
PAX8 paired box 8
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRAMEF12 PRAME family member 12
PRSS16 protease, serine, 16 (thymus)
PSD3 pleckstrin and Sec7 domain containing 3
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RASL12 RAS-like, family 12
RPS14 ribosomal protein S14
RTN2 reticulon 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1B sodium channel, voltage gated, type I beta subunit
SGSM3 small G protein signaling modulator 3
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SNN stannin
SNX13 sorting nexin 13
SOS2 son of sevenless homolog 2 (Drosophila)
SPTAN1 spectrin, alpha, non-erythrocytic 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STXBP6 syntaxin binding protein 6 (amisyn)
THRB thyroid hormone receptor, beta
TMEM120B transmembrane protein 120B
TMEM63A transmembrane protein 63A
TRAF3IP3 TRAF3 interacting protein 3
TTLL5 tubulin tyrosine ligase-like family member 5
TUBA3C tubulin, alpha 3c
UBA6 ubiquitin-like modifier activating enzyme 6
USP34 ubiquitin specific peptidase 34
VAV2 vav 2 guanine nucleotide exchange factor
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WNT16 wingless-type MMTV integration site family, member 16
WSCD1 WSC domain containing 1
XYLB xylulokinase homolog (H. influenzae)
YY2 YY2 transcription factor
ZNF345 zinc finger protein 345
ZNF37BP zinc finger protein 37B, pseudogene
ZNF74 zinc finger protein 74
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACAD10 acyl-CoA dehydrogenase family, member 10
ACTN4 actinin, alpha 4
ADGRE5 adhesion G protein-coupled receptor E5
ANXA2P3 annexin A2 pseudogene 3
ARSB arylsulfatase B
C16ORF45 chromosome 16 open reading frame 45
C1ORF159 chromosome 1 open reading frame 159
CCDC85C coiled-coil domain containing 85C
CD3EAP CD3e molecule, epsilon associated protein
CENPT centromere protein T
CHMP6 charged multivesicular body protein 6
CHMP7 charged multivesicular body protein 7
CHPF chondroitin polymerizing factor
CTAGE9 CTAGE family, member 9
CTNNBIP1 catenin, beta interacting protein 1
DCAF17 DDB1 and CUL4 associated factor 17
DEAF1 DEAF1 transcription factor
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DSCAM Down syndrome cell adhesion molecule
DUSP2 dual specificity phosphatase 2
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FBRS fibrosin
FBXL6 F-box and leucine-rich repeat protein 6
FBXO2 F-box protein 2
FOSL1 FOS-like antigen 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAN gigaxonin
GFOD1 glucose-fructose oxidoreductase domain containing 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPATCH3 G patch domain containing 3
GPR87 G protein-coupled receptor 87
GPRASP1 G protein-coupled receptor associated sorting protein 1
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2BC histone cluster 1, H2bc
KIF1B kinesin family member 1B
LIN7B lin-7 homolog B (C. elegans)
LOC257152 uncharacterized LOC257152
LONP2 lon peptidase 2, peroxisomal
LYRM9 LYR motif containing 9
MAN2C1 mannosidase, alpha, class 2C, member 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MICALL2 MICAL-like 2
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MON1B MON1 secretory trafficking family member B
MT1H metallothionein 1H
MUM1 melanoma associated antigen (mutated) 1
NBEAL2 neurobeachin-like 2
NRSN2 neurensin 2
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NUPL2 nucleoporin like 2
ORAI3 ORAI calcium release-activated calcium modulator 3
OXCT1 3-oxoacid CoA transferase 1
PC pyruvate carboxylase
PCBP4 poly(rC) binding protein 4
PGPEP1 pyroglutamyl-peptidase I
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
RECQL4 RecQ protein-like 4
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIBC2 RIB43A domain with coiled-coils 2
ROM1 retinal outer segment membrane protein 1
SCAP SREBF chaperone
SECISBP2 SECIS binding protein 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SREBF1 sterol regulatory element binding transcription factor 1
STX5 syntaxin 5
TBC1D10B TBC1 domain family, member 10B
TBX19 T-box 19
TCTA T-cell leukemia translocation altered
TJP3 tight junction protein 3
TMEM180 transmembrane protein 180
TOM1 target of myb1 (chicken)
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBA3D tubulin, alpha 3d
ULK1 unc-51 like autophagy activating kinase 1
USB1 U6 snRNA biogenesis 1
VGF VGF nerve growth factor inducible
VWA1 von Willebrand factor A domain containing 1
WDR62 WD repeat domain 62
ZBTB6 zinc finger and BTB domain containing 6
ZFHX3 zinc finger homeobox 3
ZNF14 zinc finger protein 14
ZNF16 zinc finger protein 16
ZNF212 zinc finger protein 212
ZNF276 zinc finger protein 276
ZNF282 zinc finger protein 282
ZNF468 zinc finger protein 468
ZNF473 zinc finger protein 473
ZNF557 zinc finger protein 557
ZNHIT2 zinc finger, HIT-type containing 2