oxybenzone-3092 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the oxybenzone-3092 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADGRE1 adhesion G protein-coupled receptor E1
AFF3 AF4/FMR2 family, member 3
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALOX5 arachidonate 5-lipoxygenase
AMPH amphiphysin
ANK2 ankyrin 2, neuronal
ATN1 atrophin 1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
C22ORF24 chromosome 22 open reading frame 24
CASZ1 castor zinc finger 1
CBR3 carbonyl reductase 3
CCDC106 coiled-coil domain containing 106
CCL17 chemokine (C-C motif) ligand 17
CCL27 chemokine (C-C motif) ligand 27
CDC42 cell division cycle 42
CNTN1 contactin 1
COL7A1 collagen, type VII, alpha 1
COPE coatomer protein complex, subunit epsilon
CREM cAMP responsive element modulator
DCAF15 DDB1 and CUL4 associated factor 15
DDR1 discoidin domain receptor tyrosine kinase 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DLG4 discs, large homolog 4 (Drosophila)
DLX4 distal-less homeobox 4
DMP1 dentin matrix acidic phosphoprotein 1
DNAH3 dynein, axonemal, heavy chain 3
DOK5 docking protein 5
DPEP2 dipeptidase 2
DRD2 dopamine receptor D2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FBXO31 F-box protein 31
FHL1 four and a half LIM domains 1
FJX1 four jointed box 1 (Drosophila)
FOXO1 forkhead box O1
FRMD4B FERM domain containing 4B
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GLP1R glucagon-like peptide 1 receptor
GMPR guanosine monophosphate reductase
GOSR2 golgi SNAP receptor complex member 2
GRPR gastrin-releasing peptide receptor
GSK3A glycogen synthase kinase 3 alpha
GSTM5 glutathione S-transferase mu 5
GTDC1 glycosyltransferase-like domain containing 1
HDLBP high density lipoprotein binding protein
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIST1H4F histone cluster 1, H4f
HNMT histamine N-methyltransferase
HYAL1 hyaluronoglucosaminidase 1
IFITM1 interferon induced transmembrane protein 1
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIF1C kinesin family member 1C
LCAT lecithin-cholesterol acyltransferase
LECT1 leukocyte cell derived chemotaxin 1
LPP LIM domain containing preferred translocation partner in lipoma
LTBP1 latent transforming growth factor beta binding protein 1
MAP4 microtubule-associated protein 4
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MNMIP1 manchette microtubule inner protein 1
MRC2 mannose receptor, C type 2
NEBL nebulette
NEURL1 neuralized E3 ubiquitin protein ligase 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PCDH9 protocadherin 9
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDE8B phosphodiesterase 8B
PKNOX2 PBX/knotted 1 homeobox 2
PLAT plasminogen activator, tissue
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PPP1R37 protein phosphatase 1, regulatory subunit 37
PRKCE protein kinase C, epsilon
PTGES prostaglandin E synthase
RASAL1 RAS protein activator like 1 (GAP1 like)
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC22A17 solute carrier family 22, member 17
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC35F5 solute carrier family 35, member F5
SLN sarcolipin
SMTN smoothelin
SOX15 SRY (sex determining region Y)-box 15
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STRA6 stimulated by retinoic acid 6
SYT2 synaptotagmin II
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
THBS1 thrombospondin 1
TMC7 transmembrane channel-like 7
TPMT thiopurine S-methyltransferase
TYRO3 TYRO3 protein tyrosine kinase
UBE2I ubiquitin-conjugating enzyme E2I
VASH2 vasohibin 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZER1 zyg-11 related, cell cycle regulator

decreased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ANXA2P3 annexin A2 pseudogene 3
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B9D2 B9 protein domain 2
BTF3P11 basic transcription factor 3 pseudogene 11
C17ORF53 chromosome 17 open reading frame 53
C17ORF70 chromosome 17 open reading frame 70
CAMK4 calcium/calmodulin-dependent protein kinase IV
CD34 CD34 molecule
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CECR1 cat eye syndrome chromosome region, candidate 1
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CPNE7 copine VII
CRYL1 crystallin, lambda 1
CTC1 CTS telomere maintenance complex component 1
DCSTAMP dendrocyte expressed seven transmembrane protein
ELSPBP1 epididymal sperm binding protein 1
ENO3 enolase 3 (beta, muscle)
EPHA4 EPH receptor A4
ERCC2 excision repair cross-complementation group 2
EXD3 exonuclease 3'-5' domain containing 3
FAM114A1 family with sequence similarity 114, member A1
FAM135A family with sequence similarity 135, member A
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXO4 forkhead box O4
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GK3P glycerol kinase 3 pseudogene
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HDAC7 histone deacetylase 7
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AI histone cluster 1, H2ai
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HYAL3 hyaluronoglucosaminidase 3
IFI6 interferon, alpha-inducible protein 6
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JAM2 junctional adhesion molecule 2
JMJD4 jumonji domain containing 4
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF1B kinesin family member 1B
KIFC3 kinesin family member C3
LIN7A lin-7 homolog A (C. elegans)
LINC00216 long intergenic non-protein coding RNA 216
LOXL3 lysyl oxidase-like 3
LY6G6C lymphocyte antigen 6 complex, locus G6C
MED31 mediator complex subunit 31
MEFV Mediterranean fever
MYO1E myosin IE
NCS1 neuronal calcium sensor 1
NT5DC3 5'-nucleotidase domain containing 3
OXCT2 3-oxoacid CoA transferase 2
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POM121L2 POM121 transmembrane nucleoporin-like 2
POU5F1B POU class 5 homeobox 1B
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
QSER1 glutamine and serine rich 1
RPAP1 RNA polymerase II associated protein 1
SCAMP5 secretory carrier membrane protein 5
SCN10A sodium channel, voltage gated, type X alpha subunit
SETBP1 SET binding protein 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPHK1 sphingosine kinase 1
SPINT1 serine peptidase inhibitor, Kunitz type 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STAP1 signal transducing adaptor family member 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TGFBR3 transforming growth factor, beta receptor III
THEM6 thioesterase superfamily member 6
TICAM1 toll-like receptor adaptor molecule 1
TM7SF2 transmembrane 7 superfamily member 2
TMEM120B transmembrane protein 120B
TMEM53 transmembrane protein 53
TNRC6B trinucleotide repeat containing 6B
TPM3 tropomyosin 3
TUBG2 tubulin, gamma 2
TUFT1 tuftelin 1
WWC3 WWC family member 3
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF177 zinc finger protein 177
ZNF32 zinc finger protein 32
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF34 zinc finger protein 34
ZNF611 zinc finger protein 611
ZNF696 zinc finger protein 696
ZNHIT2 zinc finger, HIT-type containing 2