oxybenzone-5410 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the oxybenzone-5410 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ADAM23 ADAM metallopeptidase domain 23
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDOB aldolase B, fructose-bisphosphate
ALK anaplastic lymphoma receptor tyrosine kinase
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BHMT2 betaine--homocysteine S-methyltransferase 2
C10ORF12 chromosome 10 open reading frame 12
C17ORF59 chromosome 17 open reading frame 59
C2ORF27A chromosome 2 open reading frame 27A
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CDC14B cell division cycle 14B
CELP carboxyl ester lipase pseudogene
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLTC clathrin, heavy chain (Hc)
CNR2 cannabinoid receptor 2 (macrophage)
COL1A1 collagen, type I, alpha 1
COMT catechol-O-methyltransferase
COPE coatomer protein complex, subunit epsilon
DAPK2 death-associated protein kinase 2
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DFNA5 deafness, autosomal dominant 5
DOK5 docking protein 5
EGR2 early growth response 2
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FGF4 fibroblast growth factor 4
FMO5 flavin containing monooxygenase 5
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GPC1 glypican 1
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFITM1 interferon induced transmembrane protein 1
IFNA17 interferon, alpha 17
INHBE inhibin, beta E
KIDINS220 kinase D-interacting substrate, 220kDa
KIF21B kinesin family member 21B
KLF12 Kruppel-like factor 12
KLHL25 kelch-like family member 25
KRT6B keratin 6B, type II
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LMAN1 lectin, mannose-binding, 1
LONP2 lon peptidase 2, peroxisomal
LRP12 low density lipoprotein receptor-related protein 12
LRP5L low density lipoprotein receptor-related protein 5-like
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK8 mitogen-activated protein kinase 8
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEF2D myocyte enhancer factor 2D
MLXIP MLX interacting protein
MSR1 macrophage scavenger receptor 1
NEUROD1 neuronal differentiation 1
NNAT neuronatin
NOS1 nitric oxide synthase 1 (neuronal)
NOVA2 neuro-oncological ventral antigen 2
OASL 2'-5'-oligoadenylate synthetase-like
OR7E24 olfactory receptor, family 7, subfamily E, member 24
PARP11 poly (ADP-ribose) polymerase family, member 11
PDCD1 programmed cell death 1
PMEL premelanosome protein
PPP5C protein phosphatase 5, catalytic subunit
PRKCB protein kinase C, beta
PROX1 prospero homeobox 1
PRSS3 protease, serine, 3
PRSS53 protease, serine, 53
PTCRA pre T-cell antigen receptor alpha
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SH2D3A SH2 domain containing 3A
SIK3 SIK family kinase 3
SIM2 single-minded family bHLH transcription factor 2
SIPA1 signal-induced proliferation-associated 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC35E2 solute carrier family 35, member E2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SOGA1 suppressor of glucose, autophagy associated 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TBC1D2B TBC1 domain family, member 2B
TCP10 t-complex 10
TCP11 t-complex 11, testis-specific
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TMLHE trimethyllysine hydroxylase, epsilon
TMOD1 tropomodulin 1
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TOP3B topoisomerase (DNA) III beta
TRIM29 tripartite motif containing 29
UBXN1 UBX domain protein 1
VCX2 variable charge, X-linked 2
WDTC1 WD and tetratricopeptide repeats 1
ZBTB18 zinc finger and BTB domain containing 18
ZNF532 zinc finger protein 532

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARL15 ADP-ribosylation factor-like 15
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
B9D2 B9 protein domain 2
BAG4 BCL2-associated athanogene 4
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL9 B-cell CLL/lymphoma 9
C1ORF159 chromosome 1 open reading frame 159
C7ORF43 chromosome 7 open reading frame 43
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CFAP44 cilia and flagella associated protein 44
CHM choroideremia (Rab escort protein 1)
CHRM3 cholinergic receptor, muscarinic 3
CINP cyclin-dependent kinase 2 interacting protein
CLIC2 chloride intracellular channel 2
CRIP1 cysteine-rich protein 1 (intestinal)
CTNNBIP1 catenin, beta interacting protein 1
CUZD1 CUB and zona pellucida-like domains 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DEAF1 DEAF1 transcription factor
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DTX4 deltex 4, E3 ubiquitin ligase
DUSP2 dual specificity phosphatase 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHX2 epoxide hydrolase 2, cytoplasmic
EPPK1 epiplakin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM212B family with sequence similarity 212, member B
FILIP1L filamin A interacting protein 1-like
FOXN2 forkhead box N2
GALK1 galactokinase 1
GDAP1 ganglioside induced differentiation associated protein 1
GJA9 gap junction protein, alpha 9, 59kDa
GLB1L2 galactosidase, beta 1-like 2
GMPR guanosine monophosphate reductase
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HOXC11 homeobox C11
ITPKB inositol-trisphosphate 3-kinase B
KIAA0355 KIAA0355
KLF2 Kruppel-like factor 2
KLF7 Kruppel-like factor 7 (ubiquitous)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MFAP2 microfibrillar-associated protein 2
MTA2 metastasis associated 1 family, member 2
MTCL1 microtubule crosslinking factor 1
MXD3 MAX dimerization protein 3
NAT6 N-acetyltransferase 6 (GCN5-related)
NCAM2 neural cell adhesion molecule 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME5 NME/NM23 family member 5
NPY5R neuropeptide Y receptor Y5
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PRODH proline dehydrogenase (oxidase) 1
PRR14L proline rich 14-like
PTK6 protein tyrosine kinase 6
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
QPCT glutaminyl-peptide cyclotransferase
RAI2 retinoic acid induced 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIN2 Ras and Rab interactor 2
RNF123 ring finger protein 123
RPL13P5 ribosomal protein L13 pseudogene 5
S100A9 S100 calcium binding protein A9
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SIRT6 sirtuin 6
SIX1 SIX homeobox 1
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC46A3 solute carrier family 46, member 3
SLIT2 slit homolog 2 (Drosophila)
SND1-IT1 SND1 intronic transcript 1
SP1 Sp1 transcription factor
SPRYD7 SPRY domain containing 7
STEAP3 STEAP family member 3, metalloreductase
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TMEM183A transmembrane protein 183A
TMEM242 transmembrane protein 242
TMUB2 transmembrane and ubiquitin-like domain containing 2
TPRA1 transmembrane protein, adipocyte asscociated 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC28 tetratricopeptide repeat domain 28
TTC33 tetratricopeptide repeat domain 33
USP20 ubiquitin specific peptidase 20
VEGFB vascular endothelial growth factor B
VWA1 von Willebrand factor A domain containing 1
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBTB22 zinc finger and BTB domain containing 22
ZDHHC14 zinc finger, DHHC-type containing 14
ZFHX3 zinc finger homeobox 3
ZMAT5 zinc finger, matrin-type 5
ZNF442 zinc finger protein 442
ZNF552 zinc finger protein 552