oxybenzone-6309 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the oxybenzone-6309 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABI2 abl-interactor 2
ACVR1B activin A receptor, type IB
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ATP9A ATPase, class II, type 9A
C19ORF40 chromosome 19 open reading frame 40
C1S complement component 1, s subcomponent
CASZ1 castor zinc finger 1
CCDC88A coiled-coil domain containing 88A
CD79B CD79b molecule, immunoglobulin-associated beta
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK9 cyclin-dependent kinase 9
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEP164 centrosomal protein 164kDa
CNTFR ciliary neurotrophic factor receptor
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CRTC1 CREB regulated transcription coactivator 1
CTNS cystinosin, lysosomal cystine transporter
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DDN dendrin
DST dystonin
EDIL3 EGF-like repeats and discoidin I-like domains 3
EGR1 early growth response 1
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPHB2 EPH receptor B2
EPS8L1 EPS8-like 1
FBLN1 fibulin 1
FUT2 fucosyltransferase 2 (secretor status included)
GATA2 GATA binding protein 2
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRM1 glutamate receptor, metabotropic 1
HAUS5 HAUS augmin-like complex, subunit 5
HBS1L HBS1-like translational GTPase
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXB5 homeobox B5
IL21R interleukin 21 receptor
KANK1 KN motif and ankyrin repeat domains 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KDM4B lysine (K)-specific demethylase 4B
KIAA0753 KIAA0753
KIAA0922 KIAA0922
KIF1A kinesin family member 1A
KRIT1 KRIT1, ankyrin repeat containing
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTC4S leukotriene C4 synthase
MAP2K2 mitogen-activated protein kinase kinase 2
MARS methionyl-tRNA synthetase
MBTPS2 membrane-bound transcription factor peptidase, site 2
MR1 major histocompatibility complex, class I-related
MXD3 MAX dimerization protein 3
NCAPH2 non-SMC condensin II complex, subunit H2
NFIB nuclear factor I/B
NMT1 N-myristoyltransferase 1
NOVA2 neuro-oncological ventral antigen 2
NT5M 5',3'-nucleotidase, mitochondrial
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OVGP1 oviductal glycoprotein 1, 120kDa
OVOL2 ovo-like zinc finger 2
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PARM1 prostate androgen-regulated mucin-like protein 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PELI2 pellino E3 ubiquitin protein ligase family member 2
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
PRDX2 peroxiredoxin 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRR4 proline rich 4 (lacrimal)
PTK6 protein tyrosine kinase 6
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB3A RAB3A, member RAS oncogene family
RANGAP1 Ran GTPase activating protein 1
RBM19 RNA binding motif protein 19
RIN1 Ras and Rab interactor 1
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RRAGB Ras-related GTP binding B
RREB1 ras responsive element binding protein 1
SAMD9 sterile alpha motif domain containing 9
SAP30 Sin3A-associated protein, 30kDa
SCARB1 scavenger receptor class B, member 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SETD8 SET domain containing (lysine methyltransferase) 8
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLMO1 slowmo homolog 1 (Drosophila)
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SNX13 sorting nexin 13
SOGA1 suppressor of glucose, autophagy associated 1
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
SYMPK symplekin
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TMEM53 transmembrane protein 53
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XYLB xylulokinase homolog (H. influenzae)

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
AMT aminomethyltransferase
ANKRD40 ankyrin repeat domain 40
ARHGAP10 Rho GTPase activating protein 10
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAHD1 bromo adjacent homology domain containing 1
BEND5 BEN domain containing 5
BEX1 brain expressed, X-linked 1
BGLAP bone gamma-carboxyglutamate (gla) protein
C1RL complement component 1, r subcomponent-like
C7ORF43 chromosome 7 open reading frame 43
CAPN15 calpain 15
CCDC85C coiled-coil domain containing 85C
CDADC1 cytidine and dCMP deaminase domain containing 1
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK3 cyclin-dependent kinase 3
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDKL3 cyclin-dependent kinase-like 3
CINP cyclin-dependent kinase 2 interacting protein
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNTNAP1 contactin associated protein 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTSD cathepsin D
CTSO cathepsin O
DCAF17 DDB1 and CUL4 associated factor 17
DOLPP1 dolichyldiphosphatase 1
ELOVL4 ELOVL fatty acid elongase 4
ELP3 elongator acetyltransferase complex subunit 3
FAM127B family with sequence similarity 127, member B
FAM50B family with sequence similarity 50, member B
FANCC Fanconi anemia, complementation group C
FBXO46 F-box protein 46
GAL3ST4 galactose-3-O-sulfotransferase 4
GALK1 galactokinase 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRWD1 glutamate-rich WD repeat containing 1
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BM histone cluster 1, H2bm
HOXC8 homeobox C8
IDI2-AS1 IDI2 antisense RNA 1
IFI35 interferon-induced protein 35
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL15RA interleukin 15 receptor, alpha
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITPKC inositol-trisphosphate 3-kinase C
KATNBL1 katanin p80 subunit B-like 1
KDM4D lysine (K)-specific demethylase 4D
KIF13B kinesin family member 13B
LIMS2 LIM and senescent cell antigen-like domains 2
LMO7 LIM domain 7
LRP3 low density lipoprotein receptor-related protein 3
MFSD11 major facilitator superfamily domain containing 11
MICALL2 MICAL-like 2
MNX1 motor neuron and pancreas homeobox 1
MOXD1 monooxygenase, DBH-like 1
MRPS18C mitochondrial ribosomal protein S18C
MXRA8 matrix-remodelling associated 8
NCALD neurocalcin delta
NID2 nidogen 2 (osteonidogen)
NT5C 5', 3'-nucleotidase, cytosolic
NT5DC3 5'-nucleotidase domain containing 3
PCDHGB5 protocadherin gamma subfamily B, 5
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PRMT7 protein arginine methyltransferase 7
PRR15L proline rich 15-like
PRR3 proline rich 3
PUS1 pseudouridylate synthase 1
RABL6 RAB, member RAS oncogene family-like 6
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIBC2 RIB43A domain with coiled-coils 2
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SAA4 serum amyloid A4, constitutive
SCG2 secretogranin II
SETBP1 SET binding protein 1
SIRT6 sirtuin 6
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPATA2L spermatogenesis associated 2-like
STIM1 stromal interaction molecule 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TIAM2 T-cell lymphoma invasion and metastasis 2
TLN1 talin 1
TMEM51 transmembrane protein 51
TOR4A torsin family 4, member A
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
ULBP2 UL16 binding protein 2
ULK1 unc-51 like autophagy activating kinase 1
WFDC2 WAP four-disulfide core domain 2
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF230 zinc finger protein 230
ZNF282 zinc finger protein 282
ZNF426 zinc finger protein 426
ZNF778 zinc finger protein 778
ZNF862 zinc finger protein 862