oxybenzone-6469 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the oxybenzone-6469 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK2 aarF domain containing kinase 2
ALDOB aldolase B, fructose-bisphosphate
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASCL1 achaete-scute family bHLH transcription factor 1
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BHLHE40 basic helix-loop-helix family, member e40
BMP8B bone morphogenetic protein 8b
C1ORF54 chromosome 1 open reading frame 54
C2 complement component 2
CA9 carbonic anhydrase IX
CABP1 calcium binding protein 1
CDK13 cyclin-dependent kinase 13
CDK6 cyclin-dependent kinase 6
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CRMP1 collapsin response mediator protein 1
CSN3 casein kappa
CST1 cystatin SN
CTSS cathepsin S
CUZD1 CUB and zona pellucida-like domains 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DFNB31 deafness, autosomal recessive 31
DGCR8 DGCR8 microprocessor complex subunit
DLX2 distal-less homeobox 2
DSC3 desmocollin 3
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EDRF1 erythroid differentiation regulatory factor 1
EFNB3 ephrin-B3
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EXOC7 exocyst complex component 7
FADS2 fatty acid desaturase 2
FLJ11292
FOXG1 forkhead box G1
FST follistatin
FYB FYN binding protein
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GPNMB glycoprotein (transmembrane) nmb
HMGN5 high mobility group nucleosome binding domain 5
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGL immunoglobulin lambda locus
INHBE inhibin, beta E
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KLF13 Kruppel-like factor 13
KRT85 keratin 85, type II
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAN1A2 mannosidase, alpha, class 1A, member 2
MANBA mannosidase, beta A, lysosomal
MAPK7 mitogen-activated protein kinase 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MERTK MER proto-oncogene, tyrosine kinase
MIER2 mesoderm induction early response 1, family member 2
MR1 major histocompatibility complex, class I-related
MRC2 mannose receptor, C type 2
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP2L1 NEDD4 binding protein 2-like 1
NEK9 NIMA-related kinase 9
NEURL1 neuralized E3 ubiquitin protein ligase 1
NF1 neurofibromin 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
NUDCD3 NudC domain containing 3
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OASL 2'-5'-oligoadenylate synthetase-like
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
OSGIN1 oxidative stress induced growth inhibitor 1
PAX2 paired box 2
PLSCR4 phospholipid scramblase 4
PLXDC1 plexin domain containing 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
RDH8 retinol dehydrogenase 8 (all-trans)
RGS12 regulator of G-protein signaling 12
RNF17 ring finger protein 17
RPS4Y1 ribosomal protein S4, Y-linked 1
RUFY3 RUN and FYVE domain containing 3
RYR1 ryanodine receptor 1 (skeletal)
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SSPN sarcospan
SSTR4 somatostatin receptor 4
SYCE1L synaptonemal complex central element protein 1-like
TMEM242 transmembrane protein 242
TRIM21 tripartite motif containing 21
TSPAN32 tetraspanin 32
UNC5B unc-5 homolog B (C. elegans)
VCAN versican
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WDR78 WD repeat domain 78
XYLB xylulokinase homolog (H. influenzae)
ZFHX2 zinc finger homeobox 2
ZNF222 zinc finger protein 222
ZNF507 zinc finger protein 507

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACSF2 acyl-CoA synthetase family member 2
AFAP1 actin filament associated protein 1
AMPH amphiphysin
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATAD5 ATPase family, AAA domain containing 5
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BMP15 bone morphogenetic protein 15
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALB2 calbindin 2
CALCOCO1 calcium binding and coiled-coil domain 1
CD3D CD3d molecule, delta (CD3-TCR complex)
CENPT centromere protein T
CLIC2 chloride intracellular channel 2
CLSPN claspin
COL9A2 collagen, type IX, alpha 2
CORO7 coronin 7
CUL9 cullin 9
CXXC4 CXXC finger protein 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNAL4 dynein, axonemal, light chain 4
EFNA3 ephrin-A3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHA2 EPH receptor A2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FBXO31 F-box protein 31
GPC3 glypican 3
GPX2 glutathione peroxidase 2
GSTA4 glutathione S-transferase alpha 4
HHLA3 HERV-H LTR-associating 3
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AL histone cluster 1, H2al
HOXC4 homeobox C4
HP1BP3 heterochromatin protein 1, binding protein 3
HYAL2 hyaluronoglucosaminidase 2
INCENP inner centromere protein antigens 135/155kDa
INO80D INO80 complex subunit D
IPO8 importin 8
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0894 KIAA0894 protein
KIFAP3 kinesin-associated protein 3
KLF3 Kruppel-like factor 3 (basic)
LOC390998 ribosomal protein L10 pseudogene
LOXL3 lysyl oxidase-like 3
LRP6 low density lipoprotein receptor-related protein 6
LYPD1 LY6/PLAUR domain containing 1
LYPLA2P1 lysophospholipase II pseudogene 1
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MCC mutated in colorectal cancers
MRPL41 mitochondrial ribosomal protein L41
MTERF4 mitochondrial transcription termination factor 4
NELL2 NEL-like 2 (chicken)
NLRX1 NLR family member X1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPTX1 neuronal pentraxin I
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLD3 phospholipase D family, member 3
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PROL1 proline rich, lacrimal 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS50 protease, serine, 50
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
REEP4 receptor accessory protein 4
RNF121 ring finger protein 121
RNF208 ring finger protein 208
RPAP2 RNA polymerase II associated protein 2
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SECTM1 secreted and transmembrane 1
SLC4A2 solute carrier family 4 (anion exchanger), member 2
TAOK1 TAO kinase 1
TARP TCR gamma alternate reading frame protein
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM104 transmembrane protein 104
TMEM19 transmembrane protein 19
TRIP10 thyroid hormone receptor interactor 10
TTBK2 tau tubulin kinase 2
UBQLN4 ubiquilin 4
URM1 ubiquitin related modifier 1
VAV1 vav 1 guanine nucleotide exchange factor
VEZT vezatin, adherens junctions transmembrane protein
WDR25 WD repeat domain 25
ZNF324 zinc finger protein 324
ZNF423 zinc finger protein 423
ZNF862 zinc finger protein 862
ZSWIM1 zinc finger, SWIM-type containing 1