oxybuprocaine-1976 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the oxybuprocaine-1976 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ADARB1 adenosine deaminase, RNA-specific, B1
ADK adenosine kinase
AES amino-terminal enhancer of split
AGTR2 angiotensin II receptor, type 2
AHCYL2 adenosylhomocysteinase-like 2
ARID4A AT rich interactive domain 4A (RBP1-like)
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
BAIAP3 BAI1-associated protein 3
C14ORF1 chromosome 14 open reading frame 1
C5ORF28 chromosome 5 open reading frame 28
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CDK10 cyclin-dependent kinase 10
CHD9 chromodomain helicase DNA binding protein 9
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CNTNAP1 contactin associated protein 1
COL5A3 collagen, type V, alpha 3
CPOX coproporphyrinogen oxidase
CTSS cathepsin S
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNAAF2 dynein, axonemal, assembly factor 2
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EIF4E eukaryotic translation initiation factor 4E
ELOVL5 ELOVL fatty acid elongase 5
ERCC6L excision repair cross-complementation group 6-like
ETV5 ets variant 5
FAM172A family with sequence similarity 172, member A
FBXO5 F-box protein 5
FGFR1 fibroblast growth factor receptor 1
FYB FYN binding protein
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GPALPP1 GPALPP motifs containing 1
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HAND1 heart and neural crest derivatives expressed 1
HBEGF heparin-binding EGF-like growth factor
HBS1L HBS1-like translational GTPase
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IL2RB interleukin 2 receptor, beta
KRIT1 KRIT1, ankyrin repeat containing
KTN1 kinectin 1 (kinesin receptor)
LIN7C lin-7 homolog C (C. elegans)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRC14 leucine rich repeat containing 14
LTB4R leukotriene B4 receptor
MAGOHB mago-nashi homolog B (Drosophila)
MAGT1 magnesium transporter 1
MED4 mediator complex subunit 4
MED7 mediator complex subunit 7
MOB3B MOB kinase activator 3B
MORC3 MORC family CW-type zinc finger 3
MYL4 myosin, light chain 4, alkali; atrial, embryonic
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OVGP1 oviductal glycoprotein 1, 120kDa
PADI1 peptidyl arginine deiminase, type I
PARP16 poly (ADP-ribose) polymerase family, member 16
PCGF2 polycomb group ring finger 2
PPAP2A phosphatidic acid phosphatase type 2A
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
RGS1 regulator of G-protein signaling 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPGR retinitis pigmentosa GTPase regulator
RSF1 remodeling and spacing factor 1
SARAF store-operated calcium entry-associated regulatory factor
SCAF4 SR-related CTD-associated factor 4
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDHAF3 succinate dehydrogenase complex assembly factor 3
SGSM3 small G protein signaling modulator 3
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLK STE20-like kinase
SMC5 structural maintenance of chromosomes 5
SNORA21 small nucleolar RNA, H/ACA box 21
SPON2 spondin 2, extracellular matrix protein
SRBD1 S1 RNA binding domain 1
SRSF11 serine/arginine-rich splicing factor 11
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUMO1 small ubiquitin-like modifier 1
TANK TRAF family member-associated NFKB activator
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TCF4 transcription factor 4
THAP1 THAP domain containing, apoptosis associated protein 1
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TM2D1 TM2 domain containing 1
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TPT1 tumor protein, translationally-controlled 1
TTF2 transcription termination factor, RNA polymerase II
UFL1 UFM1-specific ligase 1
VEZF1 vascular endothelial zinc finger 1
WDR44 WD repeat domain 44
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZEB2 zinc finger E-box binding homeobox 2
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZMYM6 zinc finger, MYM-type 6
ZNF273 zinc finger protein 273
ZNF74 zinc finger protein 74

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABHD4 abhydrolase domain containing 4
ACP2 acid phosphatase 2, lysosomal
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
ANKHD1 ankyrin repeat and KH domain containing 1
C11ORF68 chromosome 11 open reading frame 68
C2ORF42 chromosome 2 open reading frame 42
C4ORF29 chromosome 4 open reading frame 29
C6ORF47 chromosome 6 open reading frame 47
CAMK1 calcium/calmodulin-dependent protein kinase I
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CNPY3 canopy FGF signaling regulator 3
COG7 component of oligomeric golgi complex 7
COMMD10 COMM domain containing 10
CORO7 coronin 7
CTDNEP1 CTD nuclear envelope phosphatase 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DCLRE1B DNA cross-link repair 1B
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DOK2 docking protein 2, 56kDa
DOK3 docking protein 3
DPH2 DPH2 homolog (S. cerevisiae)
DUSP5 dual specificity phosphatase 5
ECHDC2 enoyl CoA hydratase domain containing 2
FBXO46 F-box protein 46
FICD FIC domain containing
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATAD2A GATA zinc finger domain containing 2A
GBAP1 glucosidase, beta, acid pseudogene 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMIP GEM interacting protein
GMPPB GDP-mannose pyrophosphorylase B
GTF2IRD1 GTF2I repeat domain containing 1
HIRA histone cell cycle regulator
HIST1H1C histone cluster 1, H1c
HK1 hexokinase 1
HPS6 Hermansky-Pudlak syndrome 6
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KDM5C lysine (K)-specific demethylase 5C
LOC642236 FSHD region gene 1 pseudogene
MAP1S microtubule-associated protein 1S
MAPK3 mitogen-activated protein kinase 3
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSL2 male-specific lethal 2 homolog (Drosophila)
MTRF1 mitochondrial translational release factor 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
PCTP phosphatidylcholine transfer protein
PEPD peptidase D
PHACTR4 phosphatase and actin regulator 4
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PISD phosphatidylserine decarboxylase
POGLUT1 protein O-glucosyltransferase 1
PPAN peter pan homolog (Drosophila)
PPCS phosphopantothenoylcysteine synthetase
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PSKH1 protein serine kinase H1
RARS arginyl-tRNA synthetase
RNF123 ring finger protein 123
RNF144A ring finger protein 144A
RNMTL1 RNA methyltransferase like 1
RRP1 ribosomal RNA processing 1
SAP30L SAP30-like
SCO2 SCO2 cytochrome c oxidase assembly protein
SEC61B Sec61 beta subunit
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3GL1 SH3-domain GRB2-like 1
SIPA1 signal-induced proliferation-associated 1
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SRRD SRR1 domain containing
SUOX sulfite oxidase
TAC3 tachykinin 3
TERF2 telomeric repeat binding factor 2
TERT telomerase reverse transcriptase
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM106C transmembrane protein 106C
TMEM115 transmembrane protein 115
TMEM127 transmembrane protein 127
TNS3 tensin 3
TP53BP1 tumor protein p53 binding protein 1
TRAIP TRAF interacting protein
TSPYL1 TSPY-like 1
TXLNA taxilin alpha
UBE2O ubiquitin-conjugating enzyme E2O
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
WDR18 WD repeat domain 18
WNT10B wingless-type MMTV integration site family, member 10B
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC18 zinc finger, DHHC-type containing 18
ZMYM3 zinc finger, MYM-type 3
ZNF211 zinc finger protein 211
ZNF282 zinc finger protein 282