| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the oxybuprocaine-4115 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACPP | acid phosphatase, prostate |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADRA1A | adrenoceptor alpha 1A |
| AKR1D1 | aldo-keto reductase family 1, member D1 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ASPH | aspartate beta-hydroxylase |
| ATN1 | atrophin 1 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 |
| BTN2A3P | butyrophilin, subfamily 2, member A3, pseudogene |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCDC87 | coiled-coil domain containing 87 |
| CD22 | CD22 molecule |
| CDC5L | cell division cycle 5-like |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLTA | clathrin, light chain A |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 |
| CNTLN | centlein, centrosomal protein |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CTSF | cathepsin F |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DOCK10 | dedicator of cytokinesis 10 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 |
| FGF18 | fibroblast growth factor 18 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GEMIN7 | gem (nuclear organelle) associated protein 7 |
| GFI1 | growth factor independent 1 transcription repressor |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GPR85 | G protein-coupled receptor 85 |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HIST1H4E | histone cluster 1, H4e |
| HOXC4 | homeobox C4 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IL2RB | interleukin 2 receptor, beta |
| JAM3 | junctional adhesion molecule 3 |
| KCNC2 | potassium channel, voltage gated Shaw related subfamily C, member 2 |
| KIAA1109 | KIAA1109 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| LAMC2 | laminin, gamma 2 |
| LDB3 | LIM domain binding 3 |
| LIMK1 | LIM domain kinase 1 |
| LOC729164 | hCG1732469 |
| MAGEA6 | melanoma antigen family A6 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MOB3B | MOB kinase activator 3B |
| MPP1 | membrane protein, palmitoylated 1, 55kDa |
| MX1 | MX dynamin-like GTPase 1 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NOL10 | nucleolar protein 10 |
| NPC1 | Niemann-Pick disease, type C1 |
| OMG | oligodendrocyte myelin glycoprotein |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDPN | podoplanin |
| PEG3 | paternally expressed 3 |
| PHF7 | PHD finger protein 7 |
| PLEK | pleckstrin |
| PLSCR3 | phospholipid scramblase 3 |
| PON3 | paraoxonase 3 |
| POU3F2 | POU class 3 homeobox 2 |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRKCB | protein kinase C, beta |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RGS10 | regulator of G-protein signaling 10 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RND1 | Rho family GTPase 1 |
| RUNX1 | runt-related transcription factor 1 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| SHOX2 | short stature homeobox 2 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SIX3 | SIX homeobox 3 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| STATH | statherin |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TRD | T cell receptor delta locus |
| TTC39A | tetratricopeptide repeat domain 39A |
| ULBP1 | UL16 binding protein 1 |
| WDR62 | WD repeat domain 62 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARRB2 | arrestin, beta 2 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CA11 | carbonic anhydrase XI |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CBX8 | chromobox homolog 8 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CES3 | carboxylesterase 3 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERO1L | ERO1-like (S. cerevisiae) |
| FILIP1L | filamin A interacting protein 1-like |
| GAMT | guanidinoacetate N-methyltransferase |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR157 | G protein-coupled receptor 157 |
| GTF2I | general transcription factor IIi |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC11 | histone deacetylase 11 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AM | histone cluster 1, H2am |
| HMOX1 | heme oxygenase 1 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| INO80D | INO80 complex subunit D |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IPO8 | importin 8 |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KIAA0894 | KIAA0894 protein |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NECAP2 | NECAP endocytosis associated 2 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PARD6B | par-6 family cell polarity regulator beta |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POMT2 | protein-O-mannosyltransferase 2 |
| PROL1 | proline rich, lacrimal 1 |
| PRR14L | proline rich 14-like |
| RAB30 | RAB30, member RAS oncogene family |
| RAI2 | retinoic acid induced 2 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RFX7 | regulatory factor X, 7 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RPL10L | ribosomal protein L10-like |
| S100A9 | S100 calcium binding protein A9 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SAV1 | salvador family WW domain containing protein 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SP1 | Sp1 transcription factor |
| SSBP3 | single stranded DNA binding protein 3 |
| STAB2 | stabilin 2 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SYTL2 | synaptotagmin-like 2 |
| TEP1 | telomerase-associated protein 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TNS2 | tensin 2 |
| TRIM16 | tripartite motif containing 16 |
| TTC17 | tetratricopeptide repeat domain 17 |
| ULBP2 | UL16 binding protein 2 |
| UPK3B | uroplakin 3B |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR76 | WD repeat domain 76 |
| XYLT2 | xylosyltransferase II |
| YEATS4 | YEATS domain containing 4 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZIC1 | Zic family member 1 |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZNF675 | zinc finger protein 675 |
