oxybutynin-3168 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the oxybutynin-3168 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AEBP1 AE binding protein 1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALOXE3 arachidonate lipoxygenase 3
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATF3 activating transcription factor 3
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C14ORF1 chromosome 14 open reading frame 1
C14ORF105 chromosome 14 open reading frame 105
C8ORF4 chromosome 8 open reading frame 4
CCL5 chemokine (C-C motif) ligand 5
CDC25C cell division cycle 25C
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEP250 centrosomal protein 250kDa
CLEC2D C-type lectin domain family 2, member D
CLEC4A C-type lectin domain family 4, member A
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DCHS1 dachsous cadherin-related 1
DSPP dentin sialophosphoprotein
EDDM3B epididymal protein 3B
ETV2 ets variant 2
FAM212B family with sequence similarity 212, member B
FBXO21 F-box protein 21
FBXO24 F-box protein 24
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGF18 fibroblast growth factor 18
FH fumarate hydratase
FOSL2 FOS-like antigen 2
FYB FYN binding protein
GIF gastric intrinsic factor (vitamin B synthesis)
GLIPR1 GLI pathogenesis-related 1
GPR17 G protein-coupled receptor 17
GPR4 G protein-coupled receptor 4
HAMP hepcidin antimicrobial peptide
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2AK histone cluster 1, H2ak
HIST1H3I histone cluster 1, H3i
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
IL12B interleukin 12B
IL1R2 interleukin 1 receptor, type II
INHBE inhibin, beta E
ITGB7 integrin, beta 7
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KLHL22 kelch-like family member 22
KRT24 keratin 24, type I
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LONP2 lon peptidase 2, peroxisomal
LRRN3 leucine rich repeat neuronal 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MGAM maltase-glucoamylase
MITF microphthalmia-associated transcription factor
MKRN3 makorin ring finger protein 3
MMP3 matrix metallopeptidase 3
MORC1 MORC family CW-type zinc finger 1
MUC2 mucin 2, oligomeric mucus/gel-forming
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYCNOS MYCN opposite strand
NNMT nicotinamide N-methyltransferase
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTM neurotrimin
OASL 2'-5'-oligoadenylate synthetase-like
OPLAH 5-oxoprolinase (ATP-hydrolysing)
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PHF8 PHD finger protein 8
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PSD3 pleckstrin and Sec7 domain containing 3
PYGO1 pygopus family PHD finger 1
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RFPL2 ret finger protein-like 2
RGS20 regulator of G-protein signaling 20
SARDH sarcosine dehydrogenase
SFRP1 secreted frizzled-related protein 1
SHOX2 short stature homeobox 2
SP2 Sp2 transcription factor
SPRR2B small proline-rich protein 2B
SPTBN1 spectrin, beta, non-erythrocytic 1
SRRM2 serine/arginine repetitive matrix 2
STK11 serine/threonine kinase 11
SYCE1L synaptonemal complex central element protein 1-like
TAT tyrosine aminotransferase
TECTA tectorin alpha
TFIP11 tuftelin interacting protein 11
TNPO2 transportin 2
TYMP thymidine phosphorylase
UBE2I ubiquitin-conjugating enzyme E2I
ZC3H13 zinc finger CCCH-type containing 13
ZNF419 zinc finger protein 419
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ABHD17B abhydrolase domain containing 17B
ACAD10 acyl-CoA dehydrogenase family, member 10
ACSF2 acyl-CoA synthetase family member 2
ADGRG2 adhesion G protein-coupled receptor G2
ADM adrenomedullin
AFAP1 actin filament associated protein 1
ANP32A-IT1 ANP32A intronic transcript 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BMP4 bone morphogenetic protein 4
BPGM 2,3-bisphosphoglycerate mutase
C2ORF27A chromosome 2 open reading frame 27A
C5 complement component 5
CAMKV CaM kinase-like vesicle-associated
CCDC25 coiled-coil domain containing 25
CDK3 cyclin-dependent kinase 3
CNGB3 cyclic nucleotide gated channel beta 3
CRABP1 cellular retinoic acid binding protein 1
CTSK cathepsin K
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNAL4 dynein, axonemal, light chain 4
DOC2A double C2-like domains, alpha
DSCAM Down syndrome cell adhesion molecule
DSE dermatan sulfate epimerase
EIF5A2 eukaryotic translation initiation factor 5A2
EMID1 EMI domain containing 1
FAM186A family with sequence similarity 186, member A
FBXL2 F-box and leucine-rich repeat protein 2
FBXO31 F-box protein 31
FOXN2 forkhead box N2
GBP2 guanylate binding protein 2, interferon-inducible
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GPX2 glutathione peroxidase 2
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA5 homeobox A5
HPS6 Hermansky-Pudlak syndrome 6
INF2 inverted formin, FH2 and WH2 domain containing
IPP intracisternal A particle-promoted polypeptide
ITGA10 integrin, alpha 10
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITPKB inositol-trisphosphate 3-kinase B
KDM5C lysine (K)-specific demethylase 5C
KRT8P12 keratin 8 pseudogene 12
LDHB lactate dehydrogenase B
LIN7B lin-7 homolog B (C. elegans)
LOC257152 uncharacterized LOC257152
LOC390998 ribosomal protein L10 pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYZ lysozyme
MBTD1 mbt domain containing 1
MCOLN3 mucolipin 3
MOCS3 molybdenum cofactor synthesis 3
MPO myeloperoxidase
MTERF4 mitochondrial transcription termination factor 4
NAP1L2 nucleosome assembly protein 1-like 2
NDE1 nudE neurodevelopment protein 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NLK nemo-like kinase
NPIPB3 nuclear pore complex interacting protein family, member B3
NXPH4 neurexophilin 4
PCDHB3 protocadherin beta 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA2G15 phospholipase A2, group XV
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS22 protease, serine, 22
PTK6 protein tyrosine kinase 6
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTPRE protein tyrosine phosphatase, receptor type, E
PYCRL pyrroline-5-carboxylate reductase-like
QSER1 glutamine and serine rich 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RCAN3 RCAN family member 3
RNF121 ring finger protein 121
RNF2 ring finger protein 2
RNF31 ring finger protein 31
SCGB2A2 secretoglobin, family 2A, member 2
SH2B3 SH2B adaptor protein 3
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SRGN serglycin
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TET3 tet methylcytosine dioxygenase 3
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
UNC119 unc-119 homolog (C. elegans)
VEGFB vascular endothelial growth factor B
WNT10B wingless-type MMTV integration site family, member 10B
WWC2 WW and C2 domain containing 2
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF446 zinc finger protein 446
ZNF492 zinc finger protein 492
ZNF552 zinc finger protein 552
ZNF573 zinc finger protein 573
ZSCAN31 zinc finger and SCAN domain containing 31