oxybutynin-6770 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the oxybutynin-6770 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK2 aarF domain containing kinase 2
ATF3 activating transcription factor 3
ATF5 activating transcription factor 5
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BIN1 bridging integrator 1
BIRC3 baculoviral IAP repeat containing 3
BMP1 bone morphogenetic protein 1
BTN3A1 butyrophilin, subfamily 3, member A1
C17ORF59 chromosome 17 open reading frame 59
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCL5 chemokine (C-C motif) ligand 5
CD52 CD52 molecule
CDK14 cyclin-dependent kinase 14
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHKB choline kinase beta
CLCN7 chloride channel, voltage-sensitive 7
CXCR4 chemokine (C-X-C motif) receptor 4
DCTN1 dynactin 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DUSP9 dual specificity phosphatase 9
EFNB3 ephrin-B3
EGR1 early growth response 1
ELL elongation factor RNA polymerase II
ETV4 ets variant 4
EWSR1 EWS RNA-binding protein 1
FAM155A family with sequence similarity 155, member A
FGF6 fibroblast growth factor 6
FOS FBJ murine osteosarcoma viral oncogene homolog
FSCN1 fascin actin-bundling protein 1
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GRM1 glutamate receptor, metabotropic 1
GSAP gamma-secretase activating protein
HAUS5 HAUS augmin-like complex, subunit 5
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIPK2 homeodomain interacting protein kinase 2
HIST1H1E histone cluster 1, H1e
HRK harakiri, BCL2 interacting protein
HUS1 HUS1 checkpoint homolog (S. pombe)
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IMPG2 interphotoreceptor matrix proteoglycan 2
INHBE inhibin, beta E
IRF1 interferon regulatory factor 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KDM4B lysine (K)-specific demethylase 4B
KIAA0040 KIAA0040
KRT19P2 keratin 19 pseudogene 2
LAMC2 laminin, gamma 2
LMF1 lipase maturation factor 1
LPL lipoprotein lipase
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBNL3 muscleblind-like splicing regulator 3
MTA2 metastasis associated 1 family, member 2
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NUP88 nucleoporin 88kDa
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
PARP12 poly (ADP-ribose) polymerase family, member 12
PCNX pecanex homolog (Drosophila)
PDE4A phosphodiesterase 4A, cAMP-specific
PLD3 phospholipase D family, member 3
PLXND1 plexin D1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PVR poliovirus receptor
RND1 Rho family GTPase 1
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SPAG6 sperm associated antigen 6
TACR3 tachykinin receptor 3
TEX15 testis expressed 15
TJAP1 tight junction associated protein 1 (peripheral)
TLR2 toll-like receptor 2
TM4SF1 transmembrane 4 L six family member 1
TMEM63A transmembrane protein 63A
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNPO2 transportin 2
TRPM1 transient receptor potential cation channel, subfamily M, member 1
UPK3B uroplakin 3B
VASH2 vasohibin 2
VIPR1 vasoactive intestinal peptide receptor 1
WDR62 WD repeat domain 62
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZSCAN26 zinc finger and SCAN domain containing 26

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ALPK1 alpha-kinase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANXA2P3 annexin A2 pseudogene 3
APOLD1 apolipoprotein L domain containing 1
ATAD3A ATPase family, AAA domain containing 3A
C2ORF44 chromosome 2 open reading frame 44
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX8 chromobox homolog 8
CCP110 centriolar coiled coil protein 110kDa
CD79B CD79b molecule, immunoglobulin-associated beta
CLK2 CDC-like kinase 2
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COMMD10 COMM domain containing 10
CORT cortistatin
CRELD1 cysteine-rich with EGF-like domains 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DOCK1 dedicator of cytokinesis 1
ETAA1 Ewing tumor-associated antigen 1
FBXL12 F-box and leucine-rich repeat protein 12
FBXL6 F-box and leucine-rich repeat protein 6
FKBP5 FK506 binding protein 5
FLRT3 fibronectin leucine rich transmembrane protein 3
GAMT guanidinoacetate N-methyltransferase
GATA4 GATA binding protein 4
GID4 GID complex subunit 4
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPR27 G protein-coupled receptor 27
HIST1H1D histone cluster 1, H1d
HIST1H2BC histone cluster 1, H2bc
IFI6 interferon, alpha-inducible protein 6
KAT2A K(lysine) acetyltransferase 2A
KDM7A lysine (K)-specific demethylase 7A
KIAA0125 KIAA0125
KLF3 Kruppel-like factor 3 (basic)
LYRM9 LYR motif containing 9
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MECR mitochondrial trans-2-enoyl-CoA reductase
MED9 mediator complex subunit 9
MEFV Mediterranean fever
METTL2B methyltransferase like 2B
MPC1 mitochondrial pyruvate carrier 1
MTERF4 mitochondrial transcription termination factor 4
MXD3 MAX dimerization protein 3
NDE1 nudE neurodevelopment protein 1
NEK11 NIMA-related kinase 11
NIPAL2 NIPA-like domain containing 2
NNAT neuronatin
NPM3 nucleophosmin/nucleoplasmin 3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARP16 poly (ADP-ribose) polymerase family, member 16
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLD2 phospholipase D2
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
POMT2 protein-O-mannosyltransferase 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB8B RAB8B, member RAS oncogene family
RBM42 RNA binding motif protein 42
RFTN1 raftlin, lipid raft linker 1
RGS2 regulator of G-protein signaling 2
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPAP1 RNA polymerase II associated protein 1
S100A4 S100 calcium binding protein A4
SIGMAR1 sigma non-opioid intracellular receptor 1
SIRAL2 SIR2 antiphage like 2
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC35F6 solute carrier family 35, member F6
SLC46A3 solute carrier family 46, member 3
SLIT2 slit homolog 2 (Drosophila)
SMR3A submaxillary gland androgen regulated protein 3A
SPATA7 spermatogenesis associated 7
STK16 serine/threonine kinase 16
TBX19 T-box 19
TLN1 talin 1
TMC5 transmembrane channel-like 5
TMEM39B transmembrane protein 39B
TMEM53 transmembrane protein 53
TNS2 tensin 2
TPST2 tyrosylprotein sulfotransferase 2
TRAIP TRAF interacting protein
TSPAN5 tetraspanin 5
TTBK2 tau tubulin kinase 2
UBXN8 UBX domain protein 8
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VGF VGF nerve growth factor inducible
VN1R1 vomeronasal 1 receptor 1
WDR91 WD repeat domain 91
ZBTB39 zinc finger and BTB domain containing 39
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF227 zinc finger protein 227
ZNF250 zinc finger protein 250
ZNF428 zinc finger protein 428
ZNF768 zinc finger protein 768