| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the oxymetazoline-1431 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| AK2 | adenylate kinase 2 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATG13 | autophagy related 13 |
| BAX | BCL2-associated X protein |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| C19ORF24 | chromosome 19 open reading frame 24 |
| C22ORF24 | chromosome 22 open reading frame 24 |
| C6ORF106 | chromosome 6 open reading frame 106 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD86 | CD86 molecule |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CYB561 | cytochrome b561 |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DST | dystonin |
| DUS2 | dihydrouridine synthase 2 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EFCAB14 | EF-hand calcium binding domain 14 |
| EGR4 | early growth response 4 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM162A | family with sequence similarity 162, member A |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FCAR | Fc fragment of IgA receptor |
| FJX1 | four jointed box 1 (Drosophila) |
| FN1 | fibronectin 1 |
| FST | follistatin |
| GAB2 | GRB2-associated binding protein 2 |
| GANAB | glucosidase, alpha; neutral AB |
| GCAT | glycine C-acetyltransferase |
| GOLGA4 | golgin A4 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRB7 | growth factor receptor-bound protein 7 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HBS1L | HBS1-like translational GTPase |
| HDAC5 | histone deacetylase 5 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| JAK2 | Janus kinase 2 |
| KIZ | kizuna centrosomal protein |
| LAD1 | ladinin 1 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MEF2C | myocyte enhancer factor 2C |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MKS1 | Meckel syndrome, type 1 |
| MYO15A | myosin XVA |
| NDRG2 | NDRG family member 2 |
| NFATC2IP | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein |
| NOP16 | NOP16 nucleolar protein |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PCIF1 | PDX1 C-terminal inhibiting factor 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDLIM5 | PDZ and LIM domain 5 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PHKA2 | phosphorylase kinase, alpha 2 (liver) |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| POLG | polymerase (DNA directed), gamma |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTMA | prothymosin, alpha |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RHOH | ras homolog family member H |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SH2D1A | SH2 domain containing 1A |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPIDR | scaffolding protein involved in DNA repair |
| SRPK2 | SRSF protein kinase 2 |
| STK16 | serine/threonine kinase 16 |
| STK19 | serine/threonine kinase 19 |
| SYMPK | symplekin |
| TCL1A | T-cell leukemia/lymphoma 1A |
| TFE3 | transcription factor binding to IGHM enhancer 3 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TRIM66 | tripartite motif containing 66 |
| TUBB3 | tubulin, beta 3 class III |
| UNC45A | unc-45 homolog A (C. elegans) |
| URI1 | URI1, prefoldin-like chaperone |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF224 | zinc finger protein 224 |
| ZNF337 | zinc finger protein 337 |
| ZNF688 | zinc finger protein 688 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
| ACTL6A | actin-like 6A |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 |
| ARMC7 | armadillo repeat containing 7 |
| ASB8 | ankyrin repeat and SOCS box containing 8 |
| ATF1 | activating transcription factor 1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| AZI2 | 5-azacytidine induced 2 |
| BEX1 | brain expressed, X-linked 1 |
| BST1 | bone marrow stromal cell antigen 1 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase |
| CD2AP | CD2-associated protein |
| CDC37L1 | cell division cycle 37-like 1 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CEP83 | centrosomal protein 83kDa |
| CFAP74 | cilia and flagella associated protein 74 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CPOX | coproporphyrinogen oxidase |
| CRIPT | cysteine-rich PDZ-binding protein |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DENND4A | DENN/MADD domain containing 4A |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| E2F8 | E2F transcription factor 8 |
| EIF1B | eukaryotic translation initiation factor 1B |
| ERBB2IP | erbb2 interacting protein |
| FAM172A | family with sequence similarity 172, member A |
| FCHO1 | FCH domain only 1 |
| GPN3 | GPN-loop GTPase 3 |
| GPR27 | G protein-coupled receptor 27 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HEATR3 | HEAT repeat containing 3 |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| IFT57 | intraflagellar transport 57 |
| IL2RG | interleukin 2 receptor, gamma |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KIFAP3 | kinesin-associated protein 3 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LACTB2 | lactamase, beta 2 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 |
| LYPLA1 | lysophospholipase I |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MED23 | mediator complex subunit 23 |
| MED4 | mediator complex subunit 4 |
| MEPCE | methylphosphate capping enzyme |
| MYL12B | myosin, light chain 12B, regulatory |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma |
| NCAPH | non-SMC condensin I complex, subunit H |
| NUPL1 | nucleoporin like 1 |
| NXPH3 | neurexophilin 3 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) |
| RANBP6 | RAN binding protein 6 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF146 | ring finger protein 146 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL26 | ribosomal protein L26 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| RWDD3 | RWD domain containing 3 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SNTA1 | syntrophin, alpha 1 |
| SPIN1 | spindlin 1 |
| STXBP3 | syntaxin binding protein 3 |
| TCTN2 | tectonic family member 2 |
| TFB2M | transcription factor B2, mitochondrial |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMBIM4 | transmembrane BAX inhibitor motif containing 4 |
| TMEM127 | transmembrane protein 127 |
| TMEM184C | transmembrane protein 184C |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) |
| WDR11 | WD repeat domain 11 |
| WDR5B | WD repeat domain 5B |
| ZCCHC10 | zinc finger, CCHC domain containing 10 |
| ZEB2 | zinc finger E-box binding homeobox 2 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF14 | zinc finger protein 14 |
| ZNF250 | zinc finger protein 250 |
| ZNF304 | zinc finger protein 304 |
| ZNF443 | zinc finger protein 443 |
| ZNF606 | zinc finger protein 606 |
| ZNF91 | zinc finger protein 91 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |