| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the oxymetazoline-2114 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| APC | adenomatous polyposis coli |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| AQR | aquarius intron-binding spliceosomal factor |
| BAX | BCL2-associated X protein |
| BMP1 | bone morphogenetic protein 1 |
| BTG2 | BTG family, member 2 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| CACTIN | cactin, spliceosome C complex subunit |
| CD58 | CD58 molecule |
| CDK6 | cyclin-dependent kinase 6 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 |
| CLIC2 | chloride intracellular channel 2 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DCTN2 | dynactin 2 (p50) |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| DUSP2 | dual specificity phosphatase 2 |
| EML2 | echinoderm microtubule associated protein like 2 |
| EPHB4 | EPH receptor B4 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FAM212B | family with sequence similarity 212, member B |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| FNDC4 | fibronectin type III domain containing 4 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GOLGA2 | golgin A2 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HIRA | histone cell cycle regulator |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H3G | histone cluster 1, H3g |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HOOK1 | hook microtubule-tethering protein 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KIF5C | kinesin family member 5C |
| KYNU | kynureninase |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| METTL5 | methyltransferase like 5 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MT1M | metallothionein 1M |
| MTSS1L | metastasis suppressor 1-like |
| NCKAP1 | NCK-associated protein 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PAX8 | paired box 8 |
| PDAP1 | PDGFA associated protein 1 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RAB27B | RAB27B, member RAS oncogene family |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| REST | RE1-silencing transcription factor |
| RGS4 | regulator of G-protein signaling 4 |
| RNF43 | ring finger protein 43 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RWDD2A | RWD domain containing 2A |
| SAP30 | Sin3A-associated protein, 30kDa |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
| SENP5 | SUMO1/sentrin specific peptidase 5 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SMAD5 | SMAD family member 5 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SRCAP | Snf2-related CREBBP activator protein |
| SRRM2 | serine/arginine repetitive matrix 2 |
| TBX2 | T-box 2 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TM2D1 | TM2 domain containing 1 |
| TMEM212 | transmembrane protein 212 |
| TMEM259 | transmembrane protein 259 |
| TRIM14 | tripartite motif containing 14 |
| TRIM62 | tripartite motif containing 62 |
| TRIP11 | thyroid hormone receptor interactor 11 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| USB1 | U6 snRNA biogenesis 1 |
| WDR91 | WD repeat domain 91 |
| ZNF41 | zinc finger protein 41 |
| ZNF510 | zinc finger protein 510 |
| ZNF669 | zinc finger protein 669 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACKR3 | atypical chemokine receptor 3 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ARMC6 | armadillo repeat containing 6 |
| ARRB2 | arrestin, beta 2 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BTBD2 | BTB (POZ) domain containing 2 |
| C11ORF71 | chromosome 11 open reading frame 71 |
| CABIN1 | calcineurin binding protein 1 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CFAP44 | cilia and flagella associated protein 44 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CHMP6 | charged multivesicular body protein 6 |
| CLDN15 | claudin 15 |
| CRYBA2 | crystallin, beta A2 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DBR1 | debranching RNA lariats 1 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 |
| DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| ECM1 | extracellular matrix protein 1 |
| EVPL | envoplakin |
| FAM155A | family with sequence similarity 155, member A |
| FANCC | Fanconi anemia, complementation group C |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GID4 | GID complex subunit 4 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 |
| GTPBP2 | GTP binding protein 2 |
| HIST1H2AE | histone cluster 1, H2ae |
| HOXC5 | homeobox C5 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IMPACT | impact RWD domain protein |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IREB2 | iron-responsive element binding protein 2 |
| KLC2 | kinesin light chain 2 |
| KRT16 | keratin 16, type I |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LRRC61 | leucine rich repeat containing 61 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MVP | major vault protein |
| MX1 | MX dynamin-like GTPase 1 |
| MYLK | myosin light chain kinase |
| MYO1E | myosin IE |
| NABP2 | nucleic acid binding protein 2 |
| NBEAL2 | neurobeachin-like 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 |
| ORC1 | origin recognition complex, subunit 1 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PC | pyruvate carboxylase |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHGDH | phosphoglycerate dehydrogenase |
| PLD3 | phospholipase D family, member 3 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| POLM | polymerase (DNA directed), mu |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRMT7 | protein arginine methyltransferase 7 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RNMTL1 | RNA methyltransferase like 1 |
| SALL2 | spalt-like transcription factor 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SPEG | SPEG complex locus |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TEX40 | testis expressed 40 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TLN1 | talin 1 |
| TMEM104 | transmembrane protein 104 |
| TRIM21 | tripartite motif containing 21 |
| TRIM45 | tripartite motif containing 45 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TUBB2B | tubulin, beta 2B class IIb |
| TWISTNB | TWIST neighbor |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF606 | zinc finger protein 606 |
| ZNF787 | zinc finger protein 787 |
| ZNF8 | zinc finger protein 8 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
