oxytetracycline-1553 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the oxytetracycline-1553 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
AGRP agouti related neuropeptide
APH1A APH1A gamma secretase subunit
AQP8 aquaporin 8
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARNTL aryl hydrocarbon receptor nuclear translocator-like
AXL AXL receptor tyrosine kinase
BCL6 B-cell CLL/lymphoma 6
CCL20 chemokine (C-C motif) ligand 20
CCNT1 cyclin T1
CCR1 chemokine (C-C motif) receptor 1
CD300A CD300a molecule
CEL carboxyl ester lipase
CER1 cerberus 1, DAN family BMP antagonist
CHKA choline kinase alpha
CLEC5A C-type lectin domain family 5, member A
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CSH2 chorionic somatomammotropin hormone 2
CYB561 cytochrome b561
DUSP2 dual specificity phosphatase 2
DUSP8 dual specificity phosphatase 8
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EMP1 epithelial membrane protein 1
EPHB2 EPH receptor B2
EXT2 exostosin glycosyltransferase 2
FCMR Fc fragment of IgM receptor
FN1 fibronectin 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR63 G protein-coupled receptor 63
GPSM3 G-protein signaling modulator 3
GSK3A glycogen synthase kinase 3 alpha
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HCAR3 hydroxycarboxylic acid receptor 3
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIST1H3E histone cluster 1, H3e
HOXA10 homeobox A10
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IDS iduronate 2-sulfatase
IFIH1 interferon induced with helicase C domain 1
ITGB5 integrin, beta 5
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JRKL JRK-like
KATNBL1 katanin p80 subunit B-like 1
KLF6 Kruppel-like factor 6
LAD1 ladinin 1
LPP LIM domain containing preferred translocation partner in lipoma
MED31 mediator complex subunit 31
MMP19 matrix metallopeptidase 19
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MST1 macrophage stimulating 1
NPPA natriuretic peptide A
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUP214 nucleoporin 214kDa
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
ORC4 origin recognition complex, subunit 4
OSBPL2 oxysterol binding protein-like 2
OVGP1 oviductal glycoprotein 1, 120kDa
PDLIM5 PDZ and LIM domain 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PECAM1 platelet/endothelial cell adhesion molecule 1
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PLSCR1 phospholipid scramblase 1
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRDM2 PR domain containing 2, with ZNF domain
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PTK2 protein tyrosine kinase 2
PTX3 pentraxin 3, long
RBM47 RNA binding motif protein 47
RGS13 regulator of G-protein signaling 13
RIMS2 regulating synaptic membrane exocytosis 2
RPP25 ribonuclease P/MRP 25kDa subunit
RPS2 ribosomal protein S2
SEC23IP SEC23 interacting protein
SH3BP2 SH3-domain binding protein 2
SIGLEC15 sialic acid binding Ig-like lectin 15
SIRT6 sirtuin 6
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SOS1 son of sevenless homolog 1 (Drosophila)
SP3 Sp3 transcription factor
SPRY4 sprouty homolog 4 (Drosophila)
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
TDRD3 tudor domain containing 3
THBS3 thrombospondin 3
TMEM97 transmembrane protein 97
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAF3IP3 TRAF3 interacting protein 3
TSFM Ts translation elongation factor, mitochondrial
TSPYL2 TSPY-like 2
WAS Wiskott-Aldrich syndrome
WDR1 WD repeat domain 1
ZBED1 zinc finger, BED-type containing 1
ZNF292 zinc finger protein 292
ZNF408 zinc finger protein 408

decreased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ADAT1 adenosine deaminase, tRNA-specific 1
ALPK1 alpha-kinase 1
AMT aminomethyltransferase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ATG4A autophagy related 4A, cysteine peptidase
ATP13A1 ATPase type 13A1
BMS1 BMS1 ribosome biogenesis factor
C11ORF48
C1GALT1C1 C1GALT1-specific chaperone 1
C1QTNF1 C1q and tumor necrosis factor related protein 1
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLDN15 claudin 15
CLTCL1 clathrin, heavy chain-like 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
COMMD3 COMM domain containing 3
COMMD9 COMM domain containing 9
COQ4 coenzyme Q4
DCP1A decapping mRNA 1A
DCPS decapping enzyme, scavenger
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DYM dymeclin
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ERH enhancer of rudimentary homolog (Drosophila)
GMPPB GDP-mannose pyrophosphorylase B
GSTCD glutathione S-transferase, C-terminal domain containing
HACD3 3-hydroxyacyl-CoA dehydratase 3
HOMER1 homer scaffolding protein 1
HSPA4L heat shock 70kDa protein 4-like
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
IFITM3 interferon induced transmembrane protein 3
IFNA17 interferon, alpha 17
KDM5C lysine (K)-specific demethylase 5C
LIAS lipoic acid synthetase
MACROD1 MACRO domain containing 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MBTPS1 membrane-bound transcription factor peptidase, site 1
MCM10 minichromosome maintenance complex component 10
MPDU1 mannose-P-dolichol utilization defect 1
MPV17 MpV17 mitochondrial inner membrane protein
MRGBP MRG/MORF4L binding protein
MRPL28 mitochondrial ribosomal protein L28
MRPS34 mitochondrial ribosomal protein S34
MUTYH mutY homolog
NCAPH non-SMC condensin I complex, subunit H
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
NECAB3 N-terminal EF-hand calcium binding protein 3
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NME3 NME/NM23 nucleoside diphosphate kinase 3
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
OGFRL1 opioid growth factor receptor-like 1
ORC1 origin recognition complex, subunit 1
PAK1IP1 PAK1 interacting protein 1
PCTP phosphatidylcholine transfer protein
PES1 pescadillo ribosomal biogenesis factor 1
PISD phosphatidylserine decarboxylase
POM121 POM121 transmembrane nucleoporin
PRMT3 protein arginine methyltransferase 3
PTGES2 prostaglandin E synthase 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RABL6 RAB, member RAS oncogene family-like 6
SDAD1 SDA1 domain containing 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SF3B2 splicing factor 3b, subunit 2, 145kDa
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNORA21 small nucleolar RNA, H/ACA box 21
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
STAR steroidogenic acute regulatory protein
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TBL3 transducin (beta)-like 3
TERT telomerase reverse transcriptase
THAP1 THAP domain containing, apoptosis associated protein 1
TMEM38B transmembrane protein 38B
TOR4A torsin family 4, member A
TSLIG3A tRNA splicing ligase complex subunit 3A
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
USPL1 ubiquitin specific peptidase like 1
VSIG4 V-set and immunoglobulin domain containing 4
WDR46 WD repeat domain 46
WT1-AS WT1 antisense RNA
XPA xeroderma pigmentosum, complementation group A
YEATS4 YEATS domain containing 4
ZBTB39 zinc finger and BTB domain containing 39
ZNF430 zinc finger protein 430
ZNF516 zinc finger protein 516
ZNF652 zinc finger protein 652