oxytetracycline-5772 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the oxytetracycline-5772 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACACB acetyl-CoA carboxylase beta
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AIM2 absent in melanoma 2
AOC2 amine oxidase, copper containing 2 (retina-specific)
APC2 adenomatosis polyposis coli 2
ARSD arylsulfatase D
ATP9A ATPase, class II, type 9A
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BDKRB1 bradykinin receptor B1
C14ORF1 chromosome 14 open reading frame 1
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CALB2 calbindin 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD52 CD52 molecule
CD86 CD86 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLEC5A C-type lectin domain family 5, member A
COL9A2 collagen, type IX, alpha 2
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DRD2 dopamine receptor D2
EHD2 EH-domain containing 2
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESRRG estrogen-related receptor gamma
FETUB fetuin B
FGF1 fibroblast growth factor 1 (acidic)
FGF12 fibroblast growth factor 12
FKRP fukutin related protein
FRY furry homolog (Drosophila)
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
GH1 growth hormone 1
GK glycerol kinase
GK3P glycerol kinase 3 pseudogene
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR17 G protein-coupled receptor 17
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
ING4 inhibitor of growth family, member 4
IRS4 insulin receptor substrate 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF13A kinesin family member 13A
LBP lipopolysaccharide binding protein
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAN2A2 mannosidase, alpha, class 2A, member 2
MAP7D3 MAP7 domain containing 3
MED25 mediator complex subunit 25
MMP25 matrix metallopeptidase 25
MSR1 macrophage scavenger receptor 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYO15A myosin XVA
NF1 neurofibromin 1
NME5 NME/NM23 family member 5
NXPH3 neurexophilin 3
OLAH oleoyl-ACP hydrolase
OPRL1 opiate receptor-like 1
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKNOX2 PBX/knotted 1 homeobox 2
POU5F1B POU class 5 homeobox 1B
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRMT2 protein arginine methyltransferase 2
PSG1 pregnancy specific beta-1-glycoprotein 1
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAD23B RAD23 homolog B (S. cerevisiae)
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RCE1 Ras converting CAAX endopeptidase 1
RIMS2 regulating synaptic membrane exocytosis 2
RUNX1 runt-related transcription factor 1
S1PR1 sphingosine-1-phosphate receptor 1
SCN1A sodium channel, voltage gated, type I alpha subunit
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SP4 Sp4 transcription factor
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SVIL supervillin
SYCE1L synaptonemal complex central element protein 1-like
TBX1 T-box 1
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
THBS4 thrombospondin 4
TIMELESS timeless circadian clock
TLR4 toll-like receptor 4
TP63 tumor protein p63
TPM3 tropomyosin 3
TTC12 tetratricopeptide repeat domain 12
VCL vinculin
VTN vitronectin

decreased expression

Symbol Name
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARL15 ADP-ribosylation factor-like 15
ATP7B ATPase, Cu++ transporting, beta polypeptide
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BEND5 BEN domain containing 5
BGLAP bone gamma-carboxyglutamate (gla) protein
C1ORF112 chromosome 1 open reading frame 112
C1RL complement component 1, r subcomponent-like
C9ORF40 chromosome 9 open reading frame 40
CDH7 cadherin 7, type 2
CDKL3 cyclin-dependent kinase-like 3
CDT1 chromatin licensing and DNA replication factor 1
CHEK2 checkpoint kinase 2
CLCA1 chloride channel accessory 1
CLEC2B C-type lectin domain family 2, member B
CPED1 cadherin-like and PC-esterase domain containing 1
CTC1 CTS telomere maintenance complex component 1
CXCL3 chemokine (C-X-C motif) ligand 3
DBF4B DBF4 zinc finger B
ELP6 elongator acetyltransferase complex subunit 6
ERCC2 excision repair cross-complementation group 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM102A family with sequence similarity 102, member A
FAT4 FAT atypical cadherin 4
FGF13 fibroblast growth factor 13
FMOD fibromodulin
FRS3 fibroblast growth factor receptor substrate 3
GAN gigaxonin
GAREM GRB2 associated, regulator of MAPK1
HIST1H1D histone cluster 1, H1d
HIST1H3G histone cluster 1, H3g
HMHA1 histocompatibility (minor) HA-1
HOXC10 homeobox C10
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFT54 intraflagellar transport 54
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
INO80D INO80 complex subunit D
ISYNA1 inositol-3-phosphate synthase 1
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KRT75 keratin 75, type II
LIMS2 LIM and senescent cell antigen-like domains 2
LNPEP leucyl/cystinyl aminopeptidase
LPCAT3 lysophosphatidylcholine acyltransferase 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MFGE8 milk fat globule-EGF factor 8 protein
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MMRN2 multimerin 2
MYL9 myosin, light chain 9, regulatory
MYO1F myosin IF
NDRG4 NDRG family member 4
NKX3-2 NK3 homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSMR oncostatin M receptor
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCDH17 protocadherin 17
PHEX phosphate regulating endopeptidase homolog, X-linked
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLA2G15 phospholipase A2, group XV
PLD3 phospholipase D family, member 3
PODXL2 podocalyxin-like 2
POMT2 protein-O-mannosyltransferase 2
PPP1R26 protein phosphatase 1, regulatory subunit 26
PTPRH protein tyrosine phosphatase, receptor type, H
RAB3A RAB3A, member RAS oncogene family
RGCC regulator of cell cycle
RHOBTB1 Rho-related BTB domain containing 1
RHOBTB2 Rho-related BTB domain containing 2
RIBC2 RIB43A domain with coiled-coils 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPP25 ribonuclease P/MRP 25kDa subunit
RUSC2 RUN and SH3 domain containing 2
SARS2 seryl-tRNA synthetase 2, mitochondrial
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC46A3 solute carrier family 46, member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
STAG3 stromal antigen 3
STARD5 StAR-related lipid transfer (START) domain containing 5
SUGCT succinyl-CoA:glutarate-CoA transferase
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TBC1D17 TBC1 domain family, member 17
TMEM177 transmembrane protein 177
TMSB15A thymosin beta 15a
TOM1 target of myb1 (chicken)
TRAF2 TNF receptor-associated factor 2
TUBA4B tubulin, alpha 4b
USB1 U6 snRNA biogenesis 1
WNT10B wingless-type MMTV integration site family, member 10B
ZNF205 zinc finger protein 205
ZNF254 zinc finger protein 254
ZNF492 zinc finger protein 492
ZNF668 zinc finger protein 668
ZNF702P zinc finger protein 702, pseudogene
ZNF768 zinc finger protein 768
ZNF778 zinc finger protein 778
ZNF84 zinc finger protein 84