ozagrel-3503 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the ozagrel-3503 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACAA2 acetyl-CoA acyltransferase 2
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ADD2 adducin 2 (beta)
ADGRB1 adhesion G protein-coupled receptor B1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGAP33 Rho GTPase activating protein 33
ARMCX2 armadillo repeat containing, X-linked 2
ASB4 ankyrin repeat and SOCS box containing 4
CADM4 cell adhesion molecule 4
CARD9 caspase recruitment domain family, member 9
CCDC57 coiled-coil domain containing 57
CD82 CD82 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CHD5 chromodomain helicase DNA binding protein 5
CHGB chromogranin B
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLCN6 chloride channel, voltage-sensitive 6
CORO2B coronin, actin binding protein, 2B
CYLD cylindromatosis (turban tumor syndrome)
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNASE1L2 deoxyribonuclease I-like 2
DOK2 docking protein 2, 56kDa
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ESRRA estrogen-related receptor alpha
EVX1 even-skipped homeobox 1
EXT1 exostosin glycosyltransferase 1
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCMR Fc fragment of IgM receptor
FOSL2 FOS-like antigen 2
GFER growth factor, augmenter of liver regeneration
GJA4 gap junction protein, alpha 4, 37kDa
GSK3A glycogen synthase kinase 3 alpha
GUCA1B guanylate cyclase activator 1B (retina)
HAS1 hyaluronan synthase 1
HEG1 heart development protein with EGF-like domains 1
HLA-C major histocompatibility complex, class I, C
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
IL11 interleukin 11
IL1RN interleukin 1 receptor antagonist
IL2RB interleukin 2 receptor, beta
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KLF6 Kruppel-like factor 6
KPNA5 karyopherin alpha 5 (importin alpha 6)
LAMA4 laminin, alpha 4
LBX1 ladybird homeobox 1
LPAR4 lysophosphatidic acid receptor 4
LTBP4 latent transforming growth factor beta binding protein 4
MAOB monoamine oxidase B
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MUC2 mucin 2, oligomeric mucus/gel-forming
MYCNOS MYCN opposite strand
MYH7 myosin, heavy chain 7, cardiac muscle, beta
NEUROD1 neuronal differentiation 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NIPAL2 NIPA-like domain containing 2
NNMT nicotinamide N-methyltransferase
OSGIN1 oxidative stress induced growth inhibitor 1
PCDHB12 protocadherin beta 12
PDCD6 programmed cell death 6
PDE4D phosphodiesterase 4D, cAMP-specific
PNPLA3 patatin-like phospholipase domain containing 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRB3 proline-rich protein BstNI subfamily 3
PTHLH parathyroid hormone-like hormone
PTPRM protein tyrosine phosphatase, receptor type, M
PTRF polymerase I and transcript release factor
PVR poliovirus receptor
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAP2B RAP2B, member of RAS oncogene family
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPS3A ribosomal protein S3A
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SKIL SKI-like proto-oncogene
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SNPH syntaphilin
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRSF7 serine/arginine-rich splicing factor 7
STAT2 signal transducer and activator of transcription 2, 113kDa
TBC1D2B TBC1 domain family, member 2B
TMEM212 transmembrane protein 212
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TSHR thyroid stimulating hormone receptor
UBOX5 U-box domain containing 5
UHRF1BP1L UHRF1 binding protein 1-like
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZNF224 zinc finger protein 224
ZNF423 zinc finger protein 423
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ACYP2 acylphosphatase 2, muscle type
ADAP2 ArfGAP with dual PH domains 2
ADM adrenomedullin
ARSB arylsulfatase B
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
C17ORF80 chromosome 17 open reading frame 80
C19ORF73 chromosome 19 open reading frame 73
C2ORF44 chromosome 2 open reading frame 44
CAMTA1 calmodulin binding transcription activator 1
CBX4 chromobox homolog 4
CCDC121 coiled-coil domain containing 121
CCDC186 coiled-coil domain containing 186
CCDC85C coiled-coil domain containing 85C
CCNL2 cyclin L2
CDKL3 cyclin-dependent kinase-like 3
CFD complement factor D (adipsin)
CGA glycoprotein hormones, alpha polypeptide
CHKB choline kinase beta
CNGB3 cyclic nucleotide gated channel beta 3
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DSCR3 Down syndrome critical region 3
FA2H fatty acid 2-hydroxylase
FBXL6 F-box and leucine-rich repeat protein 6
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP5 FK506 binding protein 5
FURIN furin (paired basic amino acid cleaving enzyme)
FZD4 frizzled class receptor 4
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GRTP1 growth hormone regulated TBC protein 1
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2I general transcription factor IIi
HDAC4 histone deacetylase 4
HIST1H1D histone cluster 1, H1d
IDI2-AS1 IDI2 antisense RNA 1
IMPACT impact RWD domain protein
IRF6 interferon regulatory factor 6
ITPKB inositol-trisphosphate 3-kinase B
KCTD20 potassium channel tetramerization domain containing 20
KLHL12 kelch-like family member 12
KLHL36 kelch-like family member 36
LARP6 La ribonucleoprotein domain family, member 6
LIN7A lin-7 homolog A (C. elegans)
LOC390998 ribosomal protein L10 pseudogene
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MTF1 metal-regulatory transcription factor 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD3 MAX dimerization protein 3
NMU neuromedin U
NOL12 nucleolar protein 12
NPFFR1 neuropeptide FF receptor 1
NUBPL nucleotide binding protein-like
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSGEP O-sialoglycoprotein endopeptidase
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIBF1 progesterone immunomodulatory binding factor 1
PLA2G3 phospholipase A2, group III
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RBL1 retinoblastoma-like 1
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RGS19 regulator of G-protein signaling 19
RIN2 Ras and Rab interactor 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
ROM1 retinal outer segment membrane protein 1
RPAP1 RNA polymerase II associated protein 1
SCRN3 secernin 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH3BGR SH3 domain binding glutamate-rich protein
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SRD5A3 steroid 5 alpha-reductase 3
STRN4 striatin, calmodulin binding protein 4
STX17 syntaxin 17
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNGR3 synaptogyrin 3
TAOK1 TAO kinase 1
TBX19 T-box 19
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPRA1 transmembrane protein, adipocyte asscociated 1
UBXN6 UBX domain protein 6
USP20 ubiquitin specific peptidase 20
WDR18 WD repeat domain 18
WDR25 WD repeat domain 25
WLS wntless Wnt ligand secretion mediator
ZC3H3 zinc finger CCCH-type containing 3
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFP30 ZFP30 zinc finger protein
ZNF324 zinc finger protein 324
ZNF586 zinc finger protein 586
ZNF747 zinc finger protein 747
ZNF768 zinc finger protein 768
ZSCAN26 zinc finger and SCAN domain containing 26