ozagrel-5983 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the ozagrel-5983 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACTN2 actinin, alpha 2
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALOX12 arachidonate 12-lipoxygenase
APP amyloid beta (A4) precursor protein
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARNT aryl hydrocarbon receptor nuclear translocator
ASCL1 achaete-scute family bHLH transcription factor 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BGN biglycan
CALML3 calmodulin-like 3
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC71 coiled-coil domain containing 71
CD58 CD58 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLTC clathrin, heavy chain (Hc)
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CSHL1 chorionic somatomammotropin hormone-like 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
EDNRA endothelin receptor type A
EFNB3 ephrin-B3
EPOR erythropoietin receptor
FGFBP1 fibroblast growth factor binding protein 1
FN1 fibronectin 1
FRMD8 FERM domain containing 8
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
G0S2 G0/G1 switch 2
GOLGA8A golgin A8 family, member A
GP6 glycoprotein VI (platelet)
GRIK5 glutamate receptor, ionotropic, kainate 5
HIST1H3I histone cluster 1, H3i
HLA-C major histocompatibility complex, class I, C
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KDM8 lysine (K)-specific demethylase 8
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMK1 LIM domain kinase 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MICALL1 MICAL-like 1
MIR622 microRNA 622
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NID1 nidogen 1
NNAT neuronatin
NOL10 nucleolar protein 10
NPC1 Niemann-Pick disease, type C1
NR2F1 nuclear receptor subfamily 2, group F, member 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PCDHB13 protocadherin beta 13
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PNMAL1 paraneoplastic Ma antigen family-like 1
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PQLC2 PQ loop repeat containing 2
PRR5 proline rich 5 (renal)
PTCH2 patched 2
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RFTN1 raftlin, lipid raft linker 1
RHBG Rh family, B glycoprotein (gene/pseudogene)
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SECTM1 secreted and transmembrane 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC35E2 solute carrier family 35, member E2
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SNX13 sorting nexin 13
SRSF7 serine/arginine-rich splicing factor 7
STOM stomatin
SUGP1 SURP and G patch domain containing 1
TGM2 transglutaminase 2
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TM2D1 TM2 domain containing 1
TMEM143 transmembrane protein 143
TMOD1 tropomodulin 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRBC1 T cell receptor beta constant 1
TRD T cell receptor delta locus
TRIM21 tripartite motif containing 21
TRIM3 tripartite motif containing 3
TSPAN9 tetraspanin 9
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
UBA6 ubiquitin-like modifier activating enzyme 6
USB1 U6 snRNA biogenesis 1
VCAN versican
ZDHHC8P1 zinc finger, DHHC-type containing 8 pseudogene 1
ZNF419 zinc finger protein 419
ZNF440 zinc finger protein 440
ZNF442 zinc finger protein 442
ZNF507 zinc finger protein 507
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ALG12 ALG12, alpha-1,6-mannosyltransferase
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARMC6 armadillo repeat containing 6
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
C11ORF80 chromosome 11 open reading frame 80
C19ORF40 chromosome 19 open reading frame 40
CCDC9 coiled-coil domain containing 9
CCNO cyclin O
CGREF1 cell growth regulator with EF-hand domain 1
CHKB choline kinase beta
CHMP7 charged multivesicular body protein 7
CHRM3 cholinergic receptor, muscarinic 3
CHST10 carbohydrate sulfotransferase 10
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CORT cortistatin
CSF1R colony stimulating factor 1 receptor
CTNNBIP1 catenin, beta interacting protein 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DSPP dentin sialophosphoprotein
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FAM155B family with sequence similarity 155, member B
FBRS fibrosin
FCHO1 FCH domain only 1
FGL1 fibrinogen-like 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAMT guanidinoacetate N-methyltransferase
GINS4 GINS complex subunit 4 (Sld5 homolog)
GMPR guanosine monophosphate reductase
GRB7 growth factor receptor-bound protein 7
GRWD1 glutamate-rich WD repeat containing 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HOXA4 homeobox A4
HOXD11 homeobox D11
HP1BP3 heterochromatin protein 1, binding protein 3
HYI hydroxypyruvate isomerase (putative)
IFI6 interferon, alpha-inducible protein 6
INO80D INO80 complex subunit D
IPO8 importin 8
IRAK4 interleukin-1 receptor-associated kinase 4
JMJD4 jumonji domain containing 4
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCTD7 potassium channel tetramerization domain containing 7
KREMEN2 kringle containing transmembrane protein 2
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC61 leucine rich repeat containing 61
MBNL3 muscleblind-like splicing regulator 3
MBOAT2 membrane bound O-acyltransferase domain containing 2
MOCS3 molybdenum cofactor synthesis 3
MTMR12 myotubularin related protein 12
MUM1 melanoma associated antigen (mutated) 1
MVD mevalonate (diphospho) decarboxylase
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
ONECUT2 one cut homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PDE12 phosphodiesterase 12
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PHACTR4 phosphatase and actin regulator 4
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POM121 POM121 transmembrane nucleoporin
PROL1 proline rich, lacrimal 1
RFWD3 ring finger and WD repeat domain 3
RNF170 ring finger protein 170
RPAP2 RNA polymerase II associated protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCN1B sodium channel, voltage gated, type I beta subunit
SIRAL2 SIR2 antiphage like 2
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPRY2 sprouty homolog 2 (Drosophila)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLN1 talin 1
TMEM183A transmembrane protein 183A
TRIM16 tripartite motif containing 16
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UNC119 unc-119 homolog (C. elegans)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZFP37 ZFP37 zinc finger protein
ZNF329 zinc finger protein 329
ZNF428 zinc finger protein 428
ZNF430 zinc finger protein 430
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZNF91 zinc finger protein 91