| Symbol |
Name |
|
ABCB1
|
ATP-binding cassette, sub-family B (MDR/TAP), member 1
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
|
ACACA
|
acetyl-CoA carboxylase alpha
|
|
ADAM17
|
ADAM metallopeptidase domain 17
|
|
AGER
|
advanced glycosylation end product-specific receptor
|
|
AKT1
|
v-akt murine thymoma viral oncogene homolog 1
|
|
AKT2
|
v-akt murine thymoma viral oncogene homolog 2
|
|
ALCAM
|
activated leukocyte cell adhesion molecule
|
|
AMD1
|
adenosylmethionine decarboxylase 1
|
|
ANKHD1
|
ankyrin repeat and KH domain containing 1
|
|
ANP32C
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member C
|
|
APC
|
adenomatous polyposis coli
|
|
APEX1
|
APEX nuclease (multifunctional DNA repair enzyme) 1
|
|
APOE
|
apolipoprotein E
|
|
APTR
|
Alu-mediated CDKN1A/p21 transcriptional regulator (non-protein coding)
|
|
AR
|
androgen receptor
|
|
ARID1A
|
AT rich interactive domain 1A (SWI-like)
|
|
ATF3
|
activating transcription factor 3
|
|
ATM
|
ATM serine/threonine kinase
|
|
AURKA
|
aurora kinase A
|
|
AURKB
|
aurora kinase B
|
|
AXL
|
AXL receptor tyrosine kinase
|
|
BAX
|
BCL2-associated X protein
|
|
BBC3
|
BCL2 binding component 3
|
|
BCCIP
|
BRCA2 and CDKN1A interacting protein
|
|
BCL11B
|
B-cell CLL/lymphoma 11B (zinc finger protein)
|
|
BCL2
|
B-cell CLL/lymphoma 2
|
|
BCL2L1
|
BCL2-like 1
|
|
BGN
|
biglycan
|
|
BIRC5
|
baculoviral IAP repeat containing 5
|
|
BMP2
|
bone morphogenetic protein 2
|
|
BMP4
|
bone morphogenetic protein 4
|
|
BMPR1A
|
bone morphogenetic protein receptor, type IA
|
|
BRAP
|
BRCA1 associated protein
|
|
BRCA1
|
breast cancer 1, early onset
|
|
BRCA2
|
breast cancer 2, early onset
|
|
C2ORF40
|
chromosome 2 open reading frame 40
|
|
CASK
|
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
|
CASP8
|
caspase 8, apoptosis-related cysteine peptidase
|
|
CAV1
|
caveolin 1, caveolae protein, 22kDa
|
|
CCND1
|
cyclin D1
|
|
CCND3
|
cyclin D3
|
|
CCNE1
|
cyclin E1
|
|
CD200R1
|
CD200 receptor 1
|
|
CD247
|
CD247 molecule
|
|
CD34
|
CD34 molecule
|
|
CDC25A
|
cell division cycle 25A
|
|
CDH1
|
cadherin 1, type 1, E-cadherin (epithelial)
|
|
CDH2
|
cadherin 2, type 1, N-cadherin (neuronal)
|
|
CDK1
|
cyclin-dependent kinase 1
|
|
CDK11A
|
cyclin-dependent kinase 11A
|
|
CDK2
|
cyclin-dependent kinase 2
|
|
CDK4
|
cyclin-dependent kinase 4
|
|
CDK6
|
cyclin-dependent kinase 6
|
|
CDK7
|
cyclin-dependent kinase 7
|
|
CDKN1A
|
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
|
CDKN1C
|
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
|
|
CDKN2A
|
cyclin-dependent kinase inhibitor 2A
|
|
CDKN2B
|
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
|
|
CDKN3
|
cyclin-dependent kinase inhibitor 3
|
|
CDT1
|
chromatin licensing and DNA replication factor 1
|
|
CDX2
|
caudal type homeobox 2
|
|
CELF1
|
CUGBP, Elav-like family member 1
|
|
CHEK1
|
checkpoint kinase 1
|
|
CHEK2
|
checkpoint kinase 2
|
|
CIZ1
|
CDKN1A interacting zinc finger protein 1
|
|
CLIC2
|
chloride intracellular channel 2
|
|
CLU
|
clusterin
|
|
CRYAB
|
crystallin, alpha B
|
|
CTNNB1
|
catenin (cadherin-associated protein), beta 1, 88kDa
|
|
CUL4A
|
cullin 4A
|
|
DDB1
|
damage-specific DNA binding protein 1, 127kDa
|
|
DDX3X
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
|
|
DEFB103B
|
defensin, beta 103B
|
|
DIXDC1
|
DIX domain containing 1
|
|
DLC1
|
DLC1 Rho GTPase activating protein
|
|
DLL1
|
delta-like 1 (Drosophila)
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
|
DNMT3B
|
DNA (cytosine-5-)-methyltransferase 3 beta
|
|
DOK2
|
docking protein 2, 56kDa
|
|
DRD1
|
dopamine receptor D1
|
|
DRD2
|
dopamine receptor D2
|
|
DTL
|
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
|
|
DUS2
|
dihydrouridine synthase 2
|
|
DUX4L1
|
double homeobox 4 like 1
|
|
DYRK1A
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
|
|
E2F1
|
E2F transcription factor 1
|
|
EGFR
|
epidermal growth factor receptor
|
|
EGR1
|
early growth response 1
|
|
EHMT2
|
euchromatic histone-lysine N-methyltransferase 2
|
|
ELAVL1
|
ELAV like RNA binding protein 1
|
|
ELAVL2
|
ELAV like neuron-specific RNA binding protein 2
|
|
ELAVL4
|
ELAV like neuron-specific RNA binding protein 4
|
|
ELK1
|
ELK1, member of ETS oncogene family
|
|
ENG
|
endoglin
|
|
EP300
|
E1A binding protein p300
|
|
EP400
|
E1A binding protein p400
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
|
ERBB3
|
erb-b2 receptor tyrosine kinase 3
|
|
ERCC2
|
excision repair cross-complementation group 2
|
|
ESR2
|
estrogen receptor 2 (ER beta)
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
|
FAS
|
Fas cell surface death receptor
|
|
FASLG
|
Fas ligand (TNF superfamily, member 6)
|
|
FHL2
|
four and a half LIM domains 2
|
|
FKBPL
|
FK506 binding protein like
|
|
FLG
|
filaggrin
|
|
FMN2
|
formin 2
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
|
FOXA1
|
forkhead box A1
|
|
FOXA2
|
forkhead box A2
|
|
FOXM1
|
forkhead box M1
|
|
FOXO1
|
forkhead box O1
|
|
FOXP3
|
forkhead box P3
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
|
GATA1
|
GATA binding protein 1 (globin transcription factor 1)
|
|
GNL3
|
guanine nucleotide binding protein-like 3 (nucleolar)
|
|
GNL3L
|
guanine nucleotide binding protein-like 3 (nucleolar)-like
|
|
GP6
|
glycoprotein VI (platelet)
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
|
GRB7
|
growth factor receptor-bound protein 7
|
|
GSK3B
|
glycogen synthase kinase 3 beta
|
|
GUCY2C
|
guanylate cyclase 2C
|
|
H2AFX
|
H2A histone family, member X
|
|
H2AFZ
|
H2A histone family, member Z
|
|
HDAC1
|
histone deacetylase 1
|
|
HDAC4
|
histone deacetylase 4
|
|
HDAC7
|
histone deacetylase 7
|
|
HGF
|
hepatocyte growth factor (hepapoietin A; scatter factor)
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
|
HLA-DQA1
|
major histocompatibility complex, class II, DQ alpha 1
|
|
HMMR
|
hyaluronan-mediated motility receptor (RHAMM)
|
|
HNRNPK
|
heterogeneous nuclear ribonucleoprotein K
|
|
HOTAIR
|
HOX transcript antisense RNA
|
|
HRAS
|
Harvey rat sarcoma viral oncogene homolog
|
|
HSPB1
|
heat shock 27kDa protein 1
|
|
HTRA2
|
HtrA serine peptidase 2
|
|
ID1
|
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
|
ID3
|
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
|
IFI27
|
interferon, alpha-inducible protein 27
|
|
IGF1
|
insulin-like growth factor 1 (somatomedin C)
|
|
IKBKB
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
|
ING1
|
inhibitor of growth family, member 1
|
|
ING2
|
inhibitor of growth family, member 2
|
|
INS
|
insulin
|
|
IRF1
|
interferon regulatory factor 1
|
|
IRF5
|
interferon regulatory factor 5
|
|
JUN
|
jun proto-oncogene
|
|
KAT2B
|
K(lysine) acetyltransferase 2B
|
|
KAT5
|
K(lysine) acetyltransferase 5
|
|
KAT6A
|
K(lysine) acetyltransferase 6A
|
|
KDM1A
|
lysine (K)-specific demethylase 1A
|
|
KIAA1524
|
KIAA1524
|
|
KIT
|
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
|
|
KL
|
klotho
|
|
KLF4
|
Kruppel-like factor 4 (gut)
|
|
KLF6
|
Kruppel-like factor 6
|
|
KLLN
|
killin, p53-regulated DNA replication inhibitor
|
|
KRAS
|
Kirsten rat sarcoma viral oncogene homolog
|
|
LATS2
|
large tumor suppressor kinase 2
|
|
LBH
|
limb bud and heart development
|
|
LCN1
|
lipocalin 1
|
|
LGALS1
|
lectin, galactoside-binding, soluble, 1
|
|
LGALS3
|
lectin, galactoside-binding, soluble, 3
|
|
LGALS8
|
lectin, galactoside-binding, soluble, 8
|
|
LGALS9
|
lectin, galactoside-binding, soluble, 9
|
|
LIN28A
|
lin-28 homolog A (C. elegans)
|
|
LMNA
|
lamin A/C
|
|
LRR1
|
leucine rich repeat protein 1
|
|
MAP2K1
|
mitogen-activated protein kinase kinase 1
|
|
MAP2K2
|
mitogen-activated protein kinase kinase 2
|
|
MAP3K7
|
mitogen-activated protein kinase kinase kinase 7
|
|
MAP4K1
|
mitogen-activated protein kinase kinase kinase kinase 1
|
|
MAPK1
|
mitogen-activated protein kinase 1
|
|
MAPK14
|
mitogen-activated protein kinase 14
|
|
MAPK3
|
mitogen-activated protein kinase 3
|
|
MAPK6
|
mitogen-activated protein kinase 6
|
|
MAPK8
|
mitogen-activated protein kinase 8
|
|
MAZ
|
MYC-associated zinc finger protein (purine-binding transcription factor)
|
|
MDM2
|
MDM2 proto-oncogene, E3 ubiquitin protein ligase
|
|
MDM4
|
MDM4, p53 regulator
|
|
MECOM
|
MDS1 and EVI1 complex locus
|
|
MEOX2
|
mesenchyme homeobox 2
|
|
MIR106B
|
microRNA 106b
|
|
MIR17
|
microRNA 17
|
|
MIR182
|
microRNA 182
|
|
MIR183
|
microRNA 183
|
|
MIR20A
|
microRNA 20a
|
|
MIR22
|
microRNA 22
|
|
MIR224
|
microRNA 224
|
|
MIR27A
|
microRNA 27a
|
|
MIR302A
|
microRNA 302a
|
|
MIR302B
|
microRNA 302b
|
|
MIR302C
|
microRNA 302c
|
|
MIR31
|
microRNA 31
|
|
MIR34A
|
microRNA 34a
|
|
MIR93
|
microRNA 93
|
|
MIR96
|
microRNA 96
|
|
MITF
|
microphthalmia-associated transcription factor
|
|
MKI67
|
marker of proliferation Ki-67
|
|
MKRN1
|
makorin ring finger protein 1
|
|
MMP1
|
matrix metallopeptidase 1
|
|
MMP14
|
matrix metallopeptidase 14 (membrane-inserted)
|
|
MSRB3
|
methionine sulfoxide reductase B3
|
|
MSTN
|
myostatin
|
|
MTA1
|
metastasis associated 1
|
|
MTOR
|
mechanistic target of rapamycin (serine/threonine kinase)
|
|
MUC2
|
mucin 2, oligomeric mucus/gel-forming
|
|
MUC5AC
|
mucin 5AC, oligomeric mucus/gel-forming
|
|
MYC
|
v-myc avian myelocytomatosis viral oncogene homolog
|
|
MYOCD
|
myocardin
|
|
NEWENTRY
|
Record to support submission of GeneRIFs for a gene not in Gene (human; man).
|
|
NF2
|
neurofibromin 2 (merlin)
|
|
NFKB1
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
|
|
NFYA
|
nuclear transcription factor Y, alpha
|
|
NGB
|
neuroglobin
|
|
NLRP3
|
NLR family, pyrin domain containing 3
|
|
NOTCH1
|
notch 1
|
|
NOTCH3
|
notch 3
|
|
NPM1
|
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
|
|
NSA2
|
NSA2 ribosome biogenesis homolog (S. cerevisiae)
|
|
NUMA1
|
nuclear mitotic apparatus protein 1
|
|
ODC1
|
ornithine decarboxylase 1
|
|
OGG1
|
8-oxoguanine DNA glycosylase
|
|
PAK1
|
p21 protein (Cdc42/Rac)-activated kinase 1
|
|
PAK2
|
p21 protein (Cdc42/Rac)-activated kinase 2
|
|
PARP1
|
poly (ADP-ribose) polymerase 1
|
|
PBK
|
PDZ binding kinase
|
|
PBRM1
|
polybromo 1
|
|
PCBP1
|
poly(rC) binding protein 1
|
|
PCNA
|
proliferating cell nuclear antigen
|
|
PGR
|
progesterone receptor
|
|
PIK3CG
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
|
|
PIM1
|
Pim-1 proto-oncogene, serine/threonine kinase
|
|
PKD1
|
polycystic kidney disease 1 (autosomal dominant)
|
|
PKD2
|
polycystic kidney disease 2 (autosomal dominant)
|
|
PLAGL1
|
pleiomorphic adenoma gene-like 1
|
|
PLD1
|
phospholipase D1, phosphatidylcholine-specific
|
|
PLD2
|
phospholipase D2
|
|
PLK1
|
polo-like kinase 1
|
|
POGLUT1
|
protein O-glucosyltransferase 1
|
|
POLD2P1
|
polymerase (DNA directed), delta 2, accessory subunit pseudogene 1
|
|
PPARD
|
peroxisome proliferator-activated receptor delta
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
|
PPP1R13L
|
protein phosphatase 1, regulatory subunit 13 like
|
|
PPP1R1C
|
protein phosphatase 1, regulatory (inhibitor) subunit 1C
|
|
PPP2R4
|
protein phosphatase 2A activator, regulatory subunit 4
|
|
PRKAA1
|
protein kinase, AMP-activated, alpha 1 catalytic subunit
|
|
PRKCA
|
protein kinase C, alpha
|
|
PRKCB
|
protein kinase C, beta
|
|
PRKCD
|
protein kinase C, delta
|
|
PRKDC
|
protein kinase, DNA-activated, catalytic polypeptide
|
|
PRMT6
|
protein arginine methyltransferase 6
|
|
PRTN3
|
proteinase 3
|
|
PSMD9
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
|
|
PTEN
|
phosphatase and tensin homolog
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
|
PTP4A3
|
protein tyrosine phosphatase type IVA, member 3
|
|
PVRL4
|
poliovirus receptor-related 4
|
|
RASA1
|
RAS p21 protein activator (GTPase activating protein) 1
|
|
RB1
|
retinoblastoma 1
|
|
RB1CC1
|
RB1-inducible coiled-coil 1
|
|
RBBP8
|
retinoblastoma binding protein 8
|
|
RBL2
|
retinoblastoma-like 2
|
|
RBM24
|
RNA binding motif protein 24
|
|
RBM38
|
RNA binding motif protein 38
|
|
RCHY1
|
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
|
|
RNF115
|
ring finger protein 115
|
|
RNF126
|
ring finger protein 126
|
|
RPL3
|
ribosomal protein L3
|
|
RPS6KB1
|
ribosomal protein S6 kinase, 70kDa, polypeptide 1
|
|
RUNX3
|
runt-related transcription factor 3
|
|
S100A11
|
S100 calcium binding protein A11
|
|
SALL2
|
spalt-like transcription factor 2
|
|
SEPW1
|
selenoprotein W, 1
|
|
SERINC2
|
serine incorporator 2
|
|
SET
|
SET nuclear proto-oncogene
|
|
SFN
|
stratifin
|
|
SIRT1
|
sirtuin 1
|
|
SKP2
|
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
|
|
SMAD2
|
SMAD family member 2
|
|
SMAD4
|
SMAD family member 4
|
|
SMAD7
|
SMAD family member 7
|
|
SMARCA4
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
|
|
SMARCB1
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
|
|
SNW1
|
SNW domain containing 1
|
|
SOX9
|
SRY (sex determining region Y)-box 9
|
|
SP1
|
Sp1 transcription factor
|
|
SP4
|
Sp4 transcription factor
|
|
SPRY1
|
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
|
SRPRB
|
signal recognition particle receptor, B subunit
|
|
SSBP1
|
single-stranded DNA binding protein 1, mitochondrial
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
|
STAT3
|
signal transducer and activator of transcription 3 (acute-phase response factor)
|
|
STAT6
|
signal transducer and activator of transcription 6, interleukin-4 induced
|
|
STK11
|
serine/threonine kinase 11
|
|
SUMO1
|
small ubiquitin-like modifier 1
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
|
TAF1
|
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
|
|
TBPL1
|
TBP-like 1
|
|
TBX2
|
T-box 2
|
|
TCEAL1
|
transcription elongation factor A (SII)-like 1
|
|
TCEB3
|
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
|
|
TCF3
|
transcription factor 3
|
|
TCF7
|
transcription factor 7 (T-cell specific, HMG-box)
|
|
TERT
|
telomerase reverse transcriptase
|
|
TFAP2A
|
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
|
|
TFAP2C
|
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
|
|
TFAP4
|
transcription factor AP-4 (activating enhancer binding protein 4)
|
|
TFF1
|
trefoil factor 1
|
|
TFF3
|
trefoil factor 3 (intestinal)
|
|
TGFB1
|
transforming growth factor, beta 1
|
|
TIMP3
|
TIMP metallopeptidase inhibitor 3
|
|
TMPRSS11A
|
transmembrane protease, serine 11A
|
|
TNF
|
tumor necrosis factor
|
|
TNFSF10
|
tumor necrosis factor (ligand) superfamily, member 10
|
|
TOP3A
|
topoisomerase (DNA) III alpha
|
|
TP53
|
tumor protein p53
|
|
TP53INP1
|
tumor protein p53 inducible nuclear protein 1
|
|
TP63
|
tumor protein p63
|
|
TP73
|
tumor protein p73
|
|
TPT1
|
tumor protein, translationally-controlled 1
|
|
TRERF1
|
transcriptional regulating factor 1
|
|
TRIM28
|
tripartite motif containing 28
|
|
TRIM3
|
tripartite motif containing 3
|
|
TRIM39
|
tripartite motif containing 39
|
|
TSG101
|
tumor susceptibility 101
|
|
TSPYL2
|
TSPY-like 2
|
|
TWIST1
|
twist family bHLH transcription factor 1
|
|
UBE2G1
|
ubiquitin-conjugating enzyme E2G 1
|
|
UBE2L6
|
ubiquitin-conjugating enzyme E2L 6
|
|
UHRF1
|
ubiquitin-like with PHD and ring finger domains 1
|
|
UQCC1
|
ubiquinol-cytochrome c reductase complex assembly factor 1
|
|
USP22
|
ubiquitin specific peptidase 22
|
|
VEGFA
|
vascular endothelial growth factor A
|
|
XRCC1
|
X-ray repair complementing defective repair in Chinese hamster cells 1
|
|
XRCC5
|
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
|
|
YWHAG
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
|
|
YWHAQ
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
|
|
ZBTB16
|
zinc finger and BTB domain containing 16
|
|
ZBTB17
|
zinc finger and BTB domain containing 17
|
|
ZBTB2
|
zinc finger and BTB domain containing 2
|
|
ZBTB49
|
zinc finger and BTB domain containing 49
|
|
ZBTB5
|
zinc finger and BTB domain containing 5
|
|
ZEB1
|
zinc finger E-box binding homeobox 1
|
|
ZMAT3
|
zinc finger, matrin-type 3
|
|
ZNF148
|
zinc finger protein 148
|
|
ZNF57
|
zinc finger protein 57
|
