paclitaxel-1542 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the paclitaxel-1542 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAP1 ArfGAP with dual PH domains 1
ADTRP androgen-dependent TFPI-regulating protein
AGFG1 ArfGAP with FG repeats 1
ALOX15 arachidonate 15-lipoxygenase
ANK2 ankyrin 2, neuronal
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APOL6 apolipoprotein L, 6
APOM apolipoprotein M
ARPIN actin-related protein 2/3 complex inhibitor
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASB1 ankyrin repeat and SOCS box containing 1
BMP15 bone morphogenetic protein 15
C17ORF53 chromosome 17 open reading frame 53
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC68 coiled-coil domain containing 68
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CLDN1 claudin 1
CLSPN claspin
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COBLL1 cordon-bleu WH2 repeat protein-like 1
CRYGC crystallin, gamma C
CUL7 cullin 7
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOCK5 dedicator of cytokinesis 5
DUSP4 dual specificity phosphatase 4
EMCN endomucin
FGFR2 fibroblast growth factor receptor 2
FLJ11292
FOXG1 forkhead box G1
GPC1 glypican 1
GPR176 G protein-coupled receptor 176
GPR21 G protein-coupled receptor 21
HDAC7 histone deacetylase 7
HDLBP high density lipoprotein binding protein
HFE hemochromatosis
HIGD2A HIG1 hypoxia inducible domain family, member 2A
IGSF6 immunoglobulin superfamily, member 6
IL6ST interleukin 6 signal transducer
KIAA0754 KIAA0754
LAMP3 lysosomal-associated membrane protein 3
LDLR low density lipoprotein receptor
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LMO2 LIM domain only 2 (rhombotin-like 1)
LPCAT4 lysophosphatidylcholine acyltransferase 4
LPIN1 lipin 1
LPXN leupaxin
LUZP4 leucine zipper protein 4
MAL mal, T-cell differentiation protein
MARK4 MAP/microtubule affinity-regulating kinase 4
MEF2D myocyte enhancer factor 2D
MFAP3L microfibrillar-associated protein 3-like
MLXIP MLX interacting protein
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTA1 metastasis associated 1
MVD mevalonate (diphospho) decarboxylase
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NEK9 NIMA-related kinase 9
NOD2 nucleotide-binding oligomerization domain containing 2
NOX1 NADPH oxidase 1
PBX2 pre-B-cell leukemia homeobox 2
PCNX pecanex homolog (Drosophila)
PDE10A phosphodiesterase 10A
PHF8 PHD finger protein 8
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PNPLA4 patatin-like phospholipase domain containing 4
POLL polymerase (DNA directed), lambda
POM121L2 POM121 transmembrane nucleoporin-like 2
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRODH proline dehydrogenase (oxidase) 1
RBM34 RNA binding motif protein 34
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHEB Ras homolog enriched in brain
RIMS2 regulating synaptic membrane exocytosis 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPL3L ribosomal protein L3-like
RPL7 ribosomal protein L7
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
STC1 stanniocalcin 1
SYNJ2 synaptojanin 2
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TRAIP TRAF interacting protein
TSPAN32 tetraspanin 32
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UPK2 uroplakin 2
VASP vasodilator-stimulated phosphoprotein
VCAM1 vascular cell adhesion molecule 1
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
WIZ widely interspaced zinc finger motifs
ZCCHC14 zinc finger, CCHC domain containing 14
ZIM2 zinc finger, imprinted 2
ZNF783 zinc finger family member 783
ZNF862 zinc finger protein 862
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ALPK1 alpha-kinase 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
C1ORF159 chromosome 1 open reading frame 159
C1ORF56 chromosome 1 open reading frame 56
CASP3 caspase 3, apoptosis-related cysteine peptidase
CD82 CD82 molecule
CDK3 cyclin-dependent kinase 3
CIDEC cell death-inducing DFFA-like effector c
CLCN2 chloride channel, voltage-sensitive 2
CLCN5 chloride channel, voltage-sensitive 5
CLDN9 claudin 9
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNGB3 cyclic nucleotide gated channel beta 3
CPPED1 calcineurin-like phosphoesterase domain containing 1
CROT carnitine O-octanoyltransferase
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNM1 dynamin 1
DUSP13 dual specificity phosphatase 13
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM192A family with sequence similarity 192, member A
FAM53B family with sequence similarity 53, member B
FER fer (fps/fes related) tyrosine kinase
FOSL1 FOS-like antigen 1
FSD1 fibronectin type III and SPRY domain containing 1
GAMT guanidinoacetate N-methyltransferase
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRPR gastrin-releasing peptide receptor
GSTA4 glutathione S-transferase alpha 4
HDAC5 histone deacetylase 5
HIST1H4D histone cluster 1, H4d
HMOX1 heme oxygenase 1
IFT140 intraflagellar transport 140
IRAK4 interleukin-1 receptor-associated kinase 4
IRF9 interferon regulatory factor 9
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JUNB jun B proto-oncogene
KIAA0894 KIAA0894 protein
KREMEN2 kringle containing transmembrane protein 2
LIME1 Lck interacting transmembrane adaptor 1
LINC00115 long intergenic non-protein coding RNA 115
LRP2 low density lipoprotein receptor-related protein 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP9 microtubule-associated protein 9
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCOLN1 mucolipin 1
MID1IP1 MID1 interacting protein 1
MRPL52 mitochondrial ribosomal protein L52
NAV2 neuron navigator 2
NPFFR1 neuropeptide FF receptor 1
PDGFRL platelet-derived growth factor receptor-like
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
RAB30 RAB30, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RGS19 regulator of G-protein signaling 19
RHBDD3 rhomboid domain containing 3
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF39 ring finger protein 39
ROM1 retinal outer segment membrane protein 1
RPH3AL rabphilin 3A-like (without C2 domains)
SAMHD1 SAM domain and HD domain 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SHARPIN SHANK-associated RH domain interactor
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNHG20 small nucleolar RNA host gene 20
SOAT1 sterol O-acyltransferase 1
SPINK5 serine peptidase inhibitor, Kazal type 5
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STARD13 StAR-related lipid transfer (START) domain containing 13
TEX40 testis expressed 40
TFF2 trefoil factor 2
THBS3 thrombospondin 3
TMCC2 transmembrane and coiled-coil domain family 2
TMEM180 transmembrane protein 180
TMEM62 transmembrane protein 62
TMPRSS3 transmembrane protease, serine 3
TRAF2 TNF receptor-associated factor 2
TRIM5 tripartite motif containing 5
TRPM4 transient receptor potential cation channel, subfamily M, member 4
ZBTB3 zinc finger and BTB domain containing 3
ZBTB48 zinc finger and BTB domain containing 48
ZNF253 zinc finger protein 253
ZNF324 zinc finger protein 324
ZNF34 zinc finger protein 34
ZNF432 zinc finger protein 432
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76
ZNF767P zinc finger family member 767, pseudogene
ZNF8 zinc finger protein 8
ZSCAN9 zinc finger and SCAN domain containing 9