| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the paclitaxel-1959 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACLY | ATP citrate lyase |
| ADM2 | adrenomedullin 2 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ANXA6 | annexin A6 |
| ATAD2 | ATPase family, AAA domain containing 2 |
| ATXN7L3B | ataxin 7-like 3B |
| AVPR1B | arginine vasopressin receptor 1B |
| BCL7B | B-cell CLL/lymphoma 7B |
| BLVRA | biliverdin reductase A |
| C16ORF58 | chromosome 16 open reading frame 58 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C20ORF27 | chromosome 20 open reading frame 27 |
| C9ORF16 | chromosome 9 open reading frame 16 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDC5L | cell division cycle 5-like |
| CDYL | chromodomain protein, Y-like |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| COPE | coatomer protein complex, subunit epsilon |
| CST3 | cystatin C |
| DGUOK | deoxyguanosine kinase |
| DUS2 | dihydrouridine synthase 2 |
| DUSP6 | dual specificity phosphatase 6 |
| ENSA | endosulfine alpha |
| EPHB4 | EPH receptor B4 |
| EPS8L1 | EPS8-like 1 |
| ESRRA | estrogen-related receptor alpha |
| FAM20B | family with sequence similarity 20, member B |
| FBXO42 | F-box protein 42 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GMPPB | GDP-mannose pyrophosphorylase B |
| GSTZ1 | glutathione S-transferase zeta 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HSF1 | heat shock transcription factor 1 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| KLF6 | Kruppel-like factor 6 |
| KLHDC10 | kelch domain containing 10 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LDLR | low density lipoprotein receptor |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| MRPS34 | mitochondrial ribosomal protein S34 |
| MYL9 | myosin, light chain 9, regulatory |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| PARVA | parvin, alpha |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PDLIM4 | PDZ and LIM domain 4 |
| PHF20 | PHD finger protein 20 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PIGR | polymeric immunoglobulin receptor |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PLAA | phospholipase A2-activating protein |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLXNB2 | plexin B2 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PREP | prolyl endopeptidase |
| PXN | paxillin |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAD50 | RAD50 homolog (S. cerevisiae) |
| RBM10 | RNA binding motif protein 10 |
| RBM47 | RNA binding motif protein 47 |
| RUSC2 | RUN and SH3 domain containing 2 |
| RXRA | retinoid X receptor, alpha |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 |
| SLC38A7 | solute carrier family 38, member 7 |
| SMIM8 | small integral membrane protein 8 |
| SQLE | squalene epoxidase |
| STBD1 | starch binding domain 1 |
| SURF2 | surfeit 2 |
| TAPBP | TAP binding protein (tapasin) |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 |
| TMEM159 | transmembrane protein 159 |
| TMPO | thymopoietin |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TRABD | TraB domain containing |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRIM29 | tripartite motif containing 29 |
| TSPYL2 | TSPY-like 2 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| USE1 | unconventional SNARE in the ER 1 homolog (S. cerevisiae) |
| USF2 | upstream transcription factor 2, c-fos interacting |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| YBX3 | Y box binding protein 3 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 |
| ACTL6A | actin-like 6A |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| AHR | aryl hydrocarbon receptor |
| ANPEP | alanyl (membrane) aminopeptidase |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 |
| ARMT1 | acidic residue methyltransferase 1 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATP11B | ATPase, class VI, type 11B |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| CBX3 | chromobox homolog 3 |
| CCDC6 | coiled-coil domain containing 6 |
| CDC73 | cell division cycle 73 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| CISH | cytokine inducible SH2-containing protein |
| COL4A5 | collagen, type IV, alpha 5 |
| CPOX | coproporphyrinogen oxidase |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DMXL1 | Dmx-like 1 |
| E2F8 | E2F transcription factor 8 |
| ECT2 | epithelial cell transforming 2 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 |
| FAM188A | family with sequence similarity 188, member A |
| FAM3C | family with sequence similarity 3, member C |
| FAM50B | family with sequence similarity 50, member B |
| FPGT | fucose-1-phosphate guanylyltransferase |
| GIN1 | gypsy retrotransposon integrase 1 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HIST1H2BC | histone cluster 1, H2bc |
| IFT57 | intraflagellar transport 57 |
| IRS1 | insulin receptor substrate 1 |
| ISCU | iron-sulfur cluster assembly enzyme |
| ISOC1 | isochorismatase domain containing 1 |
| JADE3 | jade family PHD finger 3 |
| KLF10 | Kruppel-like factor 10 |
| LACTB2 | lactamase, beta 2 |
| LGMN | legumain |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LIN7C | lin-7 homolog C (C. elegans) |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 |
| MED23 | mediator complex subunit 23 |
| MEX3C | mex-3 RNA binding family member C |
| MRPL19 | mitochondrial ribosomal protein L19 |
| MX1 | MX dynamin-like GTPase 1 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NEMF | nuclear export mediator factor |
| NUCB2 | nucleobindin 2 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) |
| PLA2G12A | phospholipase A2, group XIIA |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PRMT3 | protein arginine methyltransferase 3 |
| PRPF38B | pre-mRNA processing factor 38B |
| PTX3 | pentraxin 3, long |
| RAD51AP1 | RAD51 associated protein 1 |
| RINT1 | RAD50 interactor 1 |
| RPAP3 | RNA polymerase II associated protein 3 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SNX10 | sorting nexin 10 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| THAP7 | THAP domain containing 7 |
| TMEM165 | transmembrane protein 165 |
| TOB1 | transducer of ERBB2, 1 |
| TPCN1 | two pore segment channel 1 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TSPAN13 | tetraspanin 13 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) |
| UBXN2B | UBX domain protein 2B |
| USP6 | ubiquitin specific peptidase 6 |
| WASF1 | WAS protein family, member 1 |
| WDR82 | WD repeat domain 82 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZNF184 | zinc finger protein 184 |
| ZNF189 | zinc finger protein 189 |
| ZNF302 | zinc finger protein 302 |
| ZNF85 | zinc finger protein 85 |
