paclitaxel-2043 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the paclitaxel-2043 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ADK adenosine kinase
AQR aquarius intron-binding spliceosomal factor
ARR3 arrestin 3, retinal (X-arrestin)
AZI2 5-azacytidine induced 2
BBC3 BCL2 binding component 3
BLZF1 basic leucine zipper nuclear factor 1
C22ORF24 chromosome 22 open reading frame 24
CACYBP calcyclin binding protein
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDHR2 cadherin-related family member 2
CEP57 centrosomal protein 57kDa
CER1 cerberus 1, DAN family BMP antagonist
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIDEC cell death-inducing DFFA-like effector c
CPOX coproporphyrinogen oxidase
DERL1 derlin 1
DPYD dihydropyrimidine dehydrogenase
ECT2 epithelial cell transforming 2
EID1 EP300 interacting inhibitor of differentiation 1
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF5B eukaryotic translation initiation factor 5B
ELMO2 engulfment and cell motility 2
EPB41L3 erythrocyte membrane protein band 4.1-like 3
ERCC5 excision repair cross-complementation group 5
FAM188A family with sequence similarity 188, member A
FBXO46 F-box protein 46
G0S2 G0/G1 switch 2
GABPB1 GA binding protein transcription factor, beta subunit 1
GPR35 G protein-coupled receptor 35
HLA-DOA major histocompatibility complex, class II, DO alpha
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
KDM2A lysine (K)-specific demethylase 2A
KIAA1598
LAD1 ladinin 1
LECT1 leukocyte cell derived chemotaxin 1
MAGOHB mago-nashi homolog B (Drosophila)
MED14 mediator complex subunit 14
MED20 mediator complex subunit 20
MFN1 mitofusin 1
MTAP methylthioadenosine phosphorylase
MTMR2 myotubularin related protein 2
MTRF1L mitochondrial translational release factor 1-like
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NCAM1 neural cell adhesion molecule 1
ONECUT2 one cut homeobox 2
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PAPPA2 pappalysin 2
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCNXL4 pecanex-like 4 (Drosophila)
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PIDD1 p53-induced death domain protein 1
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
POU5F1B POU class 5 homeobox 1B
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PTCRA pre T-cell antigen receptor alpha
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAB11B RAB11B, member RAS oncogene family
RAD17 RAD17 homolog (S. pombe)
RALB v-ral simian leukemia viral oncogene homolog B
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RBBP5 retinoblastoma binding protein 5
RBM15B RNA binding motif protein 15B
RBM25 RNA binding motif protein 25
RCAN1 regulator of calcineurin 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL23AP32 ribosomal protein L23a pseudogene 32
RPL35A ribosomal protein L35a
RPL7 ribosomal protein L7
RPS9 ribosomal protein S9
SLC22A18 solute carrier family 22, member 18
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC7A4 solute carrier family 7, member 4
SLMO2 slowmo homolog 2 (Drosophila)
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SPIDR scaffolding protein involved in DNA repair
SRSF11 serine/arginine-rich splicing factor 11
SSR1 signal sequence receptor, alpha
SUCO SUN domain containing ossification factor
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYT13 synaptotagmin XIII
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMED7 transmembrane emp24 protein transport domain containing 7
TMPRSS6 transmembrane protease, serine 6
TOB2 transducer of ERBB2, 2
TOR1AIP1 torsin A interacting protein 1
TTF2 transcription termination factor, RNA polymerase II
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
UMPS uridine monophosphate synthetase
USP34 ubiquitin specific peptidase 34
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YIPF4 Yip1 domain family, member 4
YLPM1 YLP motif containing 1
ZC3H7B zinc finger CCCH-type containing 7B
ZFX zinc finger protein, X-linked
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ADRB2 adrenoceptor beta 2, surface
ANKRD40 ankyrin repeat domain 40
ANXA6 annexin A6
ASCC1 activating signal cointegrator 1 complex subunit 1
ASCC3 activating signal cointegrator 1 complex subunit 3
ASTE1 asteroid homolog 1 (Drosophila)
AUH AU RNA binding protein/enoyl-CoA hydratase
AURKAIP1 aurora kinase A interacting protein 1
BCL7C B-cell CLL/lymphoma 7C
BOLA1 bolA family member 1
BRIX1 BRX1, biogenesis of ribosomes
BSG basigin (Ok blood group)
CBR4 carbonyl reductase 4
CCNA1 cyclin A1
CCNC cyclin C
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CETN3 centrin, EF-hand protein, 3
CFL1 cofilin 1 (non-muscle)
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2
CS citrate synthase
CXORF21 chromosome X open reading frame 21
DCAF6 DDB1 and CUL4 associated factor 6
DCTN6 dynactin 6
DMTF1 cyclin D binding myb-like transcription factor 1
EAPP E2F-associated phosphoprotein
EDAR ectodysplasin A receptor
FANCF Fanconi anemia, complementation group F
FCHSD2 FCH and double SH3 domains 2
GATAD2A GATA zinc finger domain containing 2A
GDI1 GDP dissociation inhibitor 1
GPR27 G protein-coupled receptor 27
HARS histidyl-tRNA synthetase
HELLS helicase, lymphoid-specific
HLTF helicase-like transcription factor
HP haptoglobin
HS1BP3 HCLS1 binding protein 3
IGFLR1 IGF-like family receptor 1
INPP1 inositol polyphosphate-1-phosphatase
KIFAP3 kinesin-associated protein 3
KIZ kizuna centrosomal protein
KRT38 keratin 38, type I
MAEA macrophage erythroblast attacher
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEF1 melanoma antigen family F1
MED23 mediator complex subunit 23
MPC1 mitochondrial pyruvate carrier 1
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRPL33 mitochondrial ribosomal protein L33
MT1HL1 metallothionein 1H-like 1
MTMR6 myotubularin related protein 6
NARF nuclear prelamin A recognition factor
NCF2 neutrophil cytosolic factor 2
NISCH nischarin
NKRF NFKB repressing factor
NOP10 NOP10 ribonucleoprotein
NR1H2 nuclear receptor subfamily 1, group H, member 2
NUCLEOLIN nucleolin multifunctional protein
ORM1 orosomucoid 1
OSTM1 osteopetrosis associated transmembrane protein 1
OVGP1 oviductal glycoprotein 1, 120kDa
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PAN2 PAN2 poly(A) specific ribonuclease subunit
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PEF1 penta-EF-hand domain containing 1
PIGP phosphatidylinositol glycan anchor biosynthesis, class P
PNRC1 proline-rich nuclear receptor coactivator 1
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
RINT1 RAD50 interactor 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RSL24D1 ribosomal L24 domain containing 1
SEPHS2 selenophosphate synthetase 2
SNAP29 synaptosomal-associated protein, 29kDa
SP3 Sp3 transcription factor
STXBP3 syntaxin binding protein 3
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TMA7 translation machinery associated 7 homolog (S. cerevisiae)
TMEM14A transmembrane protein 14A
TMEM248 transmembrane protein 248
TMEM39B transmembrane protein 39B
TRIM22 tripartite motif containing 22
TRIM52 tripartite motif containing 52
TTC23 tetratricopeptide repeat domain 23
TTC4 tetratricopeptide repeat domain 4
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
UNC119B unc-119 homolog B (C. elegans)
UNC13B unc-13 homolog B (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
USP6 ubiquitin specific peptidase 6
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
WDR3 WD repeat domain 3
ZC3H12A zinc finger CCCH-type containing 12A
ZNF33B zinc finger protein 33B
ZNF408 zinc finger protein 408