paget's disease of bone Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A bone formation disease that has_material_basis_in hyperactive osteoclast which results_in abnormal osteoblast bone formation located_in skull, located_in pelvis, located_in vertebral column, located_in set of limbs. (Human Disease Ontology, DOID_5408)
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64 genes co-occuring with the disease paget's disease of bone in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
SQSTM1 sequestosome 1 2.50231
ALPPL2 alkaline phosphatase, placental-like 2 2.20203
ALPP alkaline phosphatase, placental 2.20149
ALPL alkaline phosphatase, liver/bone/kidney 2.20096
CALCA calcitonin-related polypeptide alpha 2.10904
VCP valosin containing protein 1.9108
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 1.81374
BGLAP bone gamma-carboxyglutamate (gla) protein 1.34286
NUP205 nucleoporin 205kDa 1.32105
OPTN optineurin 1.15283
DCSTAMP dendrocyte expressed seven transmembrane protein 1.07026
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.06774
CASC4 cancer susceptibility candidate 4 1.0627
PTH parathyroid hormone 1.02144
UCMA upper zone of growth plate and cartilage matrix associated 0.911433
RIN3 Ras and Rab interactor 3 0.908142
WDFY3 WD repeat and FYVE domain containing 3 0.859771
TBC1D25 TBC1 domain family, member 25 0.842163
GOLGA6A golgin A6 family, member A 0.836427
GOLGA6B golgin A6 family, member B 0.836427
ACP5 acid phosphatase 5, tartrate resistant 0.773705
SCUBE3 signal peptide, CUB domain, EGF-like 3 0.733811
ACPP acid phosphatase, prostate 0.714408
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa 0.66914
COL1A2 collagen, type I, alpha 2 0.638282
RHOT1 ras homolog family member T1 0.630813
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.609276
IBSP integrin-binding sialoprotein 0.58005
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 0.563723
FDPS farnesyl diphosphate synthase 0.543155
PRAMEF10 PRAME family member 10 0.499231
RAD23A RAD23 homolog A (S. cerevisiae) 0.486266
KIN Kin17 DNA and RNA binding protein 0.454847
CTSK cathepsin K 0.451831
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.448064
TBK1 TANK-binding kinase 1 0.437906
IL6 interleukin 6 0.43227
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.405305
MUCL1 mucin-like 1 0.399334
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 0.391885
C1ORF174 chromosome 1 open reading frame 174 0.370368
HSF2 heat shock transcription factor 2 0.369997
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.344941
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.335412
CALCR calcitonin receptor 0.33066
LRP5 low density lipoprotein receptor-related protein 5 0.31464
CTSC cathepsin C 0.306672
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 0.30342
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.300894
CRTAP cartilage associated protein 0.290462
P3H1 prolyl 3-hydroxylase 1 0.280796
OSTM1 osteopetrosis associated transmembrane protein 1 0.27687
MAPK11 mitogen-activated protein kinase 11 0.25983
PARD6A par-6 family cell polarity regulator alpha 0.259124
GH2 growth hormone 2 0.256652
KEAP1 kelch-like ECH-associated protein 1 0.247852
MYO6 myosin VI 0.243645
AHSG alpha-2-HS-glycoprotein 0.240847
LGALS8 lectin, galactoside-binding, soluble, 8 0.22454
IL6ST interleukin 6 signal transducer 0.22145
SOST sclerostin 0.212608
PDHX pyruvate dehydrogenase complex, component X 0.169571
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.166095
GCG glucagon 0.160948