pak1 Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description p21 protein (Cdc42/Rac)-activated kinase 1|This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010] (NCBI Entrez Gene Database, 5058)
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Genes

82 proteins co-occuring with the biological term pak1 in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
AJUBA ajuba LIM protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGAP15 Rho GTPase activating protein 15
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
AURKA aurora kinase A
BAD BCL2-associated agonist of cell death
BCL2 B-cell CLL/lymphoma 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
CALD1 caldesmon 1
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CASP1 caspase 1, apoptosis-related cysteine peptidase
CFL1 cofilin 1 (non-muscle)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CTBP1 C-terminal binding protein 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DSTN destrin (actin depolymerizing factor)
DYNLL1 dynein, light chain, LC8-type 1
DYNLL2 dynein, light chain, LC8-type 2
EGFR epidermal growth factor receptor
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ESR1 estrogen receptor 1
EZR ezrin
FLNA filamin A, alpha
FMR1 fragile X mental retardation 1
FOXO1 forkhead box O1
FXR1 fragile X mental retardation, autosomal homolog 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GSK3B glycogen synthase kinase 3 beta
HIST1H3A histone cluster 1, H3a
ILK integrin-linked kinase
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
KIF2C kinesin family member 2C
LIMK1 LIM domain kinase 1
LIMK2 LIM domain kinase 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MORC2 MORC family CW-type zinc finger 2
MSN moesin
MYH10 myosin, heavy chain 10, non-muscle
MYL12B myosin, light chain 12B, regulatory
MYL9 myosin, light chain 9, regulatory
NET1 neuroepithelial cell transforming 1
PA2G4 proliferation-associated 2G4, 38kDa
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PARVA parvin, alpha
PCBP1 poly(rC) binding protein 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PGAM1 phosphoglycerate mutase 1 (brain)
PGM1 phosphoglucomutase 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLK1 polo-like kinase 1
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCZ protein kinase C, zeta
PTK2 protein tyrosine kinase 2
PXN paxillin
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RDX radixin
SNAI1 snail family zinc finger 1
SPEN spen family transcriptional repressor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAT5A signal transducer and activator of transcription 5A
STMN1 stathmin 1
SYN1 synapsin I
TBCB tubulin folding cofactor B
VASP vasodilator-stimulated phosphoprotein
VIM vimentin