| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | palbociclib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the palbociclib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HELZ | helicase with zinc finger | 0.0827802 |
| TLE4 | transducin-like enhancer of split 4 | 0.0775281 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0696984 |
| MAP1B | microtubule-associated protein 1B | 0.0566096 |
| FNDC3B | fibronectin type III domain containing 3B | 0.055496 |
| FAM13A | family with sequence similarity 13, member A | 0.0548758 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0533443 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0522203 |
| FNBP1 | formin binding protein 1 | 0.0516726 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0488127 |
| SEPTIN9 | septin 9 | 0.0482215 |
| MEIS2 | Meis homeobox 2 | 0.047885 |
| VMP1 | vacuole membrane protein 1 | 0.045532 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0452098 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0446059 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0434955 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.043487 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0422945 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0420972 |
| LPIN1 | lipin 1 | 0.0410675 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0401647 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0400055 |
| MED13L | mediator complex subunit 13-like | 0.0394415 |
| MEF2A | myocyte enhancer factor 2A | 0.0393415 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0388242 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.0384348 |
| ATXN1 | ataxin 1 | 0.0381024 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0380812 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0377638 |
| PKM | pyruvate kinase, muscle | 0.0370408 |
| FAM107B | family with sequence similarity 107, member B | 0.0368694 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0360781 |
| ZNF638 | zinc finger protein 638 | 0.0356052 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0355751 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0354478 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0348738 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0345925 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.033482 |
| DST | dystonin | 0.0333555 |
| MEF2D | myocyte enhancer factor 2D | 0.0328868 |
| OGA | O-GlcNAcase | 0.0327897 |
| PCBP2 | poly(rC) binding protein 2 | 0.032414 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0323616 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0318004 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0303528 |
| RUNX1 | runt-related transcription factor 1 | 0.030247 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0301583 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.030042 |
| VEGFA | vascular endothelial growth factor A | 0.0298803 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0292862 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0290342 |
| ZNF292 | zinc finger protein 292 | 0.0287525 |
| SMAD3 | SMAD family member 3 | 0.0284472 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0280439 |
| PCM1 | pericentriolar material 1 | 0.027704 |
| HMBOX1 | homeobox containing 1 | 0.0276581 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0274878 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0274847 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0274209 |
| HDAC8 | histone deacetylase 8 | 0.0273528 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0267122 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0266624 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0266418 |
| COPA | coatomer protein complex, subunit alpha | 0.0264919 |
| GOLGA4 | golgin A4 | 0.0260619 |
| PRKCA | protein kinase C, alpha | 0.0259432 |
| CSNK1D | casein kinase 1, delta | 0.0259007 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0255426 |
| MSI2 | musashi RNA-binding protein 2 | 0.0254064 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0253826 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0253037 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0253028 |
| ACLY | ATP citrate lyase | 0.0252467 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | 0.0247048 |
| TRIM25 | tripartite motif containing 25 | 0.024585 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0242176 |
| FOXO3 | forkhead box O3 | 0.0242141 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0242026 |
| ADAR | adenosine deaminase, RNA-specific | 0.0241872 |
| OPTN | optineurin | 0.023789 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0234681 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0234104 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0232484 |
| TUFT1 | tuftelin 1 | 0.0229968 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0229278 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0227241 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0226039 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0223705 |
| TNRC6C | trinucleotide repeat containing 6C | 0.0223591 |
| ANO6 | anoctamin 6 | 0.0223469 |
| B2M | beta-2-microglobulin | 0.022343 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0222993 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0221675 |
| CCNL1 | cyclin L1 | 0.022146 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.0221038 |
| ZNF148 | zinc finger protein 148 | 0.0220294 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0220087 |
| PTK2 | protein tyrosine kinase 2 | 0.0219477 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.021947 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0218786 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.186518 |
| LSAMP | limbic system-associated membrane protein | -0.170604 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.121909 |
| VCL | vinculin | -0.116865 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0700363 |
| IGF2 | insulin-like growth factor 2 | -0.0593678 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0557028 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0523103 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0501914 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0480722 |
| COL3A1 | collagen, type III, alpha 1 | -0.0423828 |
| VIM | vimentin | -0.040662 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0405721 |
| SYT1 | synaptotagmin I | -0.0396687 |
| EXT1 | exostosin glycosyltransferase 1 | -0.039566 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0367953 |
| RPL38 | ribosomal protein L38 | -0.0364204 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0362895 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0354632 |
| PTMA | prothymosin, alpha | -0.0354246 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0352733 |
| RPS24 | ribosomal protein S24 | -0.0351655 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0346564 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0334769 |
| NREP | neuronal regeneration related protein | -0.0326561 |
| KCNIP4 | Kv channel interacting protein 4 | -0.0326042 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0325859 |
| CENPF | centromere protein F, 350/400kDa | -0.0319502 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0317393 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0313145 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0312818 |
| RAD51B | RAD51 paralog B | -0.0302918 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0301961 |
| TPM1 | tropomyosin 1 (alpha) | -0.0295211 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0292828 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0290198 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0287309 |
| LRRC7 | leucine rich repeat containing 7 | -0.0282621 |
| RPLP1 | ribosomal protein, large, P1 | -0.0278081 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0274867 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0273045 |
| PCNX4 | pecanex 4 | -0.0268906 |
| GPC5 | glypican 5 | -0.0268832 |
| AEBP2 | AE binding protein 2 | -0.026656 |
| FRMD4A | FERM domain containing 4A | -0.0260115 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.0257337 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0255215 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.02546 |
| RPL34 | ribosomal protein L34 | -0.0250915 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0249966 |
| STK38L | serine/threonine kinase 38 like | -0.0248611 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0247127 |
| TPM4 | tropomyosin 4 | -0.0245732 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0242422 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0241731 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0240127 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0237207 |
| DIAPH2 | diaphanous-related formin 2 | -0.0232997 |
| DIAPH3 | diaphanous-related formin 3 | -0.0229712 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0227734 |
| CADM2 | cell adhesion molecule 2 | -0.0227123 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | -0.022657 |
| GLCCI1 | glucocorticoid induced 1 | -0.0226237 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0223911 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0220854 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0217798 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0217686 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0215068 |
| AK1 | adenylate kinase 1 | -0.0212356 |
| ITGA1 | integrin, alpha 1 | -0.0211213 |
| RPL31 | ribosomal protein L31 | -0.0208647 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0207026 |
| PIK3C2G | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma | -0.0204664 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0202846 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0198758 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0197651 |
| CCDC47 | coiled-coil domain containing 47 | -0.019535 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0193357 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0193005 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0192371 |
| CNTN4 | contactin 4 | -0.0191461 |
| CDH13 | cadherin 13 | -0.0189497 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0188368 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0188051 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0187012 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0186628 |
| PCDH15 | protocadherin-related 15 | -0.0185711 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0181864 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0181403 |
| EDNRA | endothelin receptor type A | -0.0177795 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0176936 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.017339 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0172856 |
| EFNA5 | ephrin-A5 | -0.017198 |
| IER3 | immediate early response 3 | -0.0170907 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0169048 |
| RPL19 | ribosomal protein L19 | -0.0168925 |
| MTAP | methylthioadenosine phosphorylase | -0.0168688 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.016835 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0167982 |
